.... 1 ). Fig. 1 Immune and neural sensorial signals are jointly processed at brain levels and elicit responses of physiologic and evolutionary relevance: a proposal. The upper part of the diagram depicts the proposal that both immune and neuro-sensorial signals act and are integrated at the level...

... Abstract There is not one systems biology of aging, but two. Though aging can evolve in either sexual or asexual species when there is asymmetric reproduction, the evolutionary genetics of aging in species with frequent sexual recombination are quite different from those arising when sex...

... Abstract Evolutionary theories of aging explain why we age. These theories take into account the fact that, in the wild, mean lifespan of many species is usually shorter than it could be in protected environments. In such conditions, because most of animals die before reaching old age...

... Abstract There is growing interest in the application of evolutionary theory to medicine. In this review, we outline an evolutionary approach to the anxiety disorders. We begin by considering the nature of fear and anxiety, and their evolutionary benefits. We emphasize that fear and anxiety...

... Abstract Evolutionary and life history perspectives allow a fuller understanding of both patterns of growth and development and variations in disease risk. Evolutionary processes act to ensure successful reproduction and not the preservation of health and longevity, and this entails trade-offs...

... have given way to controlled clinical trials. Great progress has taken place in our knowledge of the physiologic and molecular mechanisms of the omega- 6/omega- 3 ratio in health and disease [ 11 , 12 ]. Evolutionary Aspects of Diet On the basis of estimates from studies on Paleolithic...

... of a contagious yawn in an observer - several researchers, e.g. Platek et al. [ 2 , 3 ] have hypothesized that contagious yawning might be an evolutionary predecessor to a more sophisticated sense of empathy/mental state attribution. In order to test this, Platek et al. [ 2 ] investigated whether...

... that differs from that for which our genetic constitution was selected. Studies on the evolutionary aspects of diet indicate that major changes have taken place in our diet, particularly in the type and amount of essential fatty acids (EFA) and in the antioxidant content of foods [ 7 - 11 ] ( fig. 1...

... Abstract Here we explore whether there is any evidence that the rapid development of the obesity epidemic in emerging nations, and its unusual coexistence with malnutrition, may have evolutionary origins that make such populations especially vulnerable to the obesogenic conditions accompanying...

... Abstract The evolutionary history of mammals, but more specifically humans, indicates that heat stress was adecisive and powerful selection pressure. There is good evidence that early hominids had to adapt toa changing environment by assuming an upright posture and consequently bipedalism...

... is of hightheoretical importance. It clears the way for ‘Mutationist’ hypotheses that may help explain bafflingadaptations and trends in eukaryotic evolution that have been largely ignored. This essayrecognizes the potential evolutionary importance of saltatory chromosomal events that maychange gene content - expand...

... Abstract Our knowledge of the symbiosis between Wolbachia and filarial nematodes has grownrapidly in recent years. Phylogenetic analyses, which highlight a coevolutionary pattern forfilarial nematodes and their wolbachiae, and molecular evolutionary analyses, showing noevidence for positive...