Search Results for epidermi

... Abstract SummaryThe metabolism of both free nucleosides and bases in hyperkeratosis induced by topical application of n-hexadecane on the epidermis of guinea pig was discussed, based on the technique of high-pressure liquid chromatography. The level of nucleosides and bases decreased...

... as previously reported. However. sodium dodecylsulfate gel electrophoresis showed mUltiple protein bands ranging from Mr < 25,000 to Mr > 200,000. The findings indicate that histidine-rich protein of different forms and solubility exists, in the epidermis and may be involved in the biological function...

... of HRPI to HRPII and b) the differential lectin-binding in the epidermis of the newborn rat.HRPI (Mol. Wgt. ≥ 106) and HRPII (Mol. Wgt. 6 × 104) have similar unique amino acid compositions and exhibit extensive—but not completehomology in primary structures as determined by peptide mapping after exposure...

... Abstract Immunohistochemical localizations of 3′,5′-cyclic AMP (cAMP) and 3′,5′-cyclic GMP (cGMP) were performed in the involved and noninvolved epidermis of psoriasis and in the normal controls. The following results were obtained:1. In the normal epidermis, cAMP was located in the cytoplasm...

... Abstract Three-day-old Sprague-Dawley rats were injected intraperitoneally with 100 μCi of [35S]cystine. They were then sacrificed at 30 minutes, 2, 4, and 10 hours. The skins were epilated by the beeswax-resin procedure and the epidermis was separated by soaking in NH4Cl solution. Neither hair...

... Abstract SummaryIt has been reported that pig skin epidermis contains at least four independent adenylate cyclase systems, i.e. 1) beta-adrenergic-, 2) histamine H2-, 3) adenosine and, 4) prostaglandin E-adenylate cyclase systems, resulting in the accumulation of cyclic AMP. Using human skin...

... Abstract During aging, the pH of the epidermis goes up and the calcium gradient goes down. Both have negative effects on the protective function of the epidermis and both are connected to each other as is discussed here. In the aging process, the pH rises from ∼5 to ∼5.5-6. The establishment...

... Abstract Actinic keratoses (AKs) are intraepithelial neoplasms formed by atypical keratinocyte proliferation. Histopathologically, typical AKs are characterized by a slightly thickened epidermis, usually with irregular downward buds, orthokeratosis alternating with parakeratosis (‘pink and blue...