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Book Chapter
Book Chapter
Series: Current Problems in Dermatology
Volume: 47
Published: 26 February 2015
10.1159/000369409
EISBN: 978-3-318-02775-4
... Abstract In this chapter, we will discuss the most common alopecias due to drugs and other skin and systemic disorders. The following hair disorders will be analyzed: telogen effluvium (acute and chronic); anagen effluvium; folliculotropic mycosis fungoides; and folliculitis due to bacteria...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 111
Published: 18 November 2014
10.1159/000362319
EISBN: 978-3-318-02667-2
... Anemia Iron deficiency Vitamin B 12 Folate Key Messages • Iron deficiency results from decreased intake in the setting of increased loss due to menstruation, childbirth or gastrointestinal bleeding. • Diets low in animal source foods are deficient in both iron and vitamin B 12...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 40
Published: 19 October 2012
10.1159/000342179
EISBN: 978-3-318-02239-1
..., and ovulatory and menstrual dysfunction, but the degree of steroid 21-OH deficiency does not always correlate with the clinical manifestations with some cases being even asymptomatic [ 4 ]. PCOS is the most common cause of oligo-ovulation and consequently of infertility due to anovulation. It is also one...
Book Chapter
Series: Frontiers in Diabetes
Volume: 21
Published: 16 February 2012
10.1159/000334513
EISBN: 978-3-8055-9944-3
... with HI-HA show increased sensitivity to leucine stimulation of insulin release and to protein-induced hypoglycemia, but not to other secretagogues such as glucose. HA appears to be due to increased renal ammonia production and is not associated with the usual symptoms of ammonia toxicity. Recent...
Book Chapter
Series: Frontiers in Diabetes
Volume: 21
Published: 16 February 2012
10.1159/000334521
EISBN: 978-3-8055-9944-3
...% of the reported cases, and 50% in the CHOP series, are afflicted with GK-HI due to de novo mutations. This high proportion of de novo cases in the CHOP series is also seen in other dominant forms of HI associated with glutamate dehydrogenase (GDH) or K ATP mutations (see the chapters by Kelly et al. [pp. 100-111...
Book Chapter
Series: Frontiers in Diabetes
Volume: 21
Published: 16 February 2012
10.1159/000334524
EISBN: 978-3-8055-9944-3
... hypoglycemia due to a role of UCP2 as a negative regulator of insulin release [ 11 ]. This latter point is discussed in more detail below. The ability of UCP2 to downregulate macrophage response and control ROS production in cells agrees with its observed role in protection against atherosclerosis, neuron...
Book Chapter
Series: Contributions to Nephrology
Volume: 172
Published: 01 September 2011
10.1159/000328699
EISBN: 978-3-8055-9795-1
... become ischemic. The hypothesis makes sense for tissues such as the kidney medulla with physiological and pathophysiological low oxygen tension [ 16 - 18 ], where the blood flow is sluggish. Furthermore, due to its important epithelial metabolic activity [ 19 ], the renal medulla is very susceptible...
Book Chapter
Book Chapter
Series: Monographs in Human Genetics
Volume: 19
Published: 07 March 2011
10.1159/000321705
EISBN: 978-3-8055-9595-7
... Abstract We summarize the novel association of trigonocephaly and polysyndactyly in 3 unrelated patients due to mutations within the GLI3 gene. GLI3 acts as a downstream mediator of the Sonic hedgehog signal-transduction pathway which is essential for early development; playing a role...
Book Chapter
Book Chapter
Book Chapter
Series: Medicine and Sport Science
Volume: 50
Published: 29 March 2007
10.1159/000101394
EISBN: 978-3-318-01396-2
... that the decline in fitness is largely due to increases in fatness. There arestrong mechanistic connections; within cohorts, variability in fatness accounts for about 20%of variability in running performance; there is a strong correlation between overweightprevalence and relative fitness across specific cohorts...
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