... Abstract Over the past decade, the neonatal literature has undergone dynamic swings vis a vis its approach to patent ductus arteriosus (PDA) therapeutics, from aggressively closing all PDA's to permissive tolerance of ductal shunting. We propose that ductal closure with paracetamol can satisfy...

...References References 1. Bose CL, Laughon MM: Patent ductus arteriosus: lack of evidence for common treatments. Arch Dis Child Fetal Neonatal Ed 2007;92:F498-F502. 2. Benitz WE: Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis? J...

..., such as combinations of growth restriction, antenatal blood flow concerns, intensive supportive needs (including inotropes), and large open patent ductus arteriosus, currently poorly represented in feeding trials. Infant tolerance monitoring includes clinical observations (stooling, abdominal size, vomiting...

... cardiac operation was performed when a patent ductus arteriosus was ligated. This was followed 6 years later by two other types of extracardiac operations. The pace quickened in the 1950s as cardiac catheterization was developed for diagnosis and methods to perform open heart operations were elaborated...

..., Cagliari (Italy), October 26–31, 2015. ABS 34. J Pediatr Neonat Individual Med 2015;4:e040250. 35. Bardanzellu F, Neroni P, Dessì A, et al: Paracetamol in patent ductus arteriosus treatment: efficacious and safe? Biomed Res Int 2017;2017:1438038. 36. Atzori L, Barberini L, Lussu M, et al...

... fromimproved management of the more mature neonates [7, 8].Chorioamnionitis, postnatal infection, and patent ductus arteriosusfurther augment the risk of secondary lung damage inthe prematurely born children [9-12]. If the consequent structuralchanges are severe enough to cause ongoing compromiseof pulmonary...

... = pulmonary artery; RV = right ventricle. Aortic Valvoplasty In neonatal critical aortic stenosis, the systemic circulation cannot be maintained by the flow through the stenotic aortic valve; adequate cardiac output is maintained via right-to-left shunting at the ductus arteriosus (fig. 2...

... parenchyma or through the bypass channel of the ductus venosus. Growth-restricted fetuses shunt more blood through the ductus venosus to spare the fetal brain, but some normal fetuses shunt 10% of nutrient-rich blood through the bypass channel while others shunt 60%. From animal studies where the ductus...

.... Davidson HR: A large family with patent ductus arteriosus and unusual face. J Med Genet 1993;30:503-505. 49. Slavotinek A, Clayton-Smith J, Super M: Familial patent ductus arteriosus: a further case of CHAR syndrome. Am J Med Genet 1997;71:229-232. 50. Satoda M, Zhao F, Diaz GA, Burn J, Goodship J...

... während den akuten Episoden. Diese Hypertension kann durch Inhalation von 100%igem Sauerstoff positiv beeinflusst werden, was zu einer Reduktion des entstandenen rechts-links Shunts über einen persistierenden Ductus arteriosus oder ein offengebliebenes Foramen ovale führt.Als Folge alveolärer...

... of fluid restriction in preterm infants with significant patent ductus arteriosus. J Pediatr. 2012;161:404–8. 13. Sardar S, Pal, S, Mishra R. A randomized controlled trial of restricted versus standard fluid management in late preterm and term infants with transient tachypnea of the newborn. J Neonatal...

... and tailored therapies. Persistent Patent Ductus Arteriosus Ductus arteriosus (DA), one of the fundamental circulation shunts occurring during fetal life, generally undergoes functional closure between 24 and 72 h of life. In the preterm newborn, spontaneous DA closure is often delayed or completely...

..., patent ductus arteriosus (PDA), ventricular septal defects, and coarctation of the aorta. The Mowat-Wilson syndrome has been attributed to mutations or deletions of ZEB2 [ 32 ], a zinc finger protein that binds to E-cadherin. The majority of ZEB2 mutations described to date are large gene deletions...