1-20 of 8041 Search Results for

drug

Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Book Chapter
Book
Book Chapter
Published: 17 August 2012
10.1159/000336443
EISBN: 978-3-8055-9930-6
... Abstract It is now well established that subgroup populations deserve a careful assessment of their response differences in order to derive maximum benefit from medical products, and that the concept of ‘one size fits all’ is an antiquated approach to drug development. These concepts...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 97
Published: 07 May 2012
10.1159/000335633
EISBN: 978-3-8055-9971-9
... Abstract Drug eruptions are common adverse events affecting approximately 3% of hospitalized patients, and can be seen with the use of almost any medication. Making a diagnosis could be challenging because no pattern is specific for a particular drug. A study of clinical aspects, histopathology...
Book Chapter
Published: 31 May 2007
10.1159/000104214
EISBN: 978-3-318-01454-9
... Abstract Skin tests with drugs can be helpful in determining the cause of cutaneous adverse drug reactions (CADR). Patch tests and prick tests can be done with any commercialized form of a drug, intradermal tests (IDT) normally rely on the availability of a sterile solution used for parental...
Book Chapter
Book Chapter
Book
Book
Book
Book
Published: 09 September 1975
10.1159/isbn.978-3-318-06196-3
EISBN: 978-3-318-06196-3
Book
Book Chapter
Series: Contributions to Nephrology
Volume: 200
Published: 07 August 2023
10.1159/000526730
EISBN: 978-3-318-07124-5
... Abstract Hemoperfusion (HP) is an extracorporeal blood purification therapy that is used to remove poisons or drugs from the body. This chapter provides a brief overview of the technical aspects and the potential indications and limitations of HP, with the focus being on the use of HP for acute...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517700
EISBN: 978-3-318-06937-2
...: The mainly prescribed drugs involved in overdose cases are opioids, benzodiazepines, and antidepressants. Antidepressants are the main psychiatric drugs that lead to kidney injury, mainly the second-generation ones. However, the prevalence of depression in dialysis patients varies from 22.8 to 39.3...
Book
Book Chapter
Series: Progress in Neurological Surgery
Volume: 35
Published: 18 December 2020
10.1159/000509623
EISBN: 978-3-318-06795-8
... Abstract Despite the high incidence of facial pain, targeted drug delivery remains a rarely used technique for treatment of otherwise refractory pain. Two distinct paths have been described. The intraventricular route allows direct access to intracerebral opioid receptors. The more recently...
Book Chapter
Series: Current Problems in Dermatology
Volume: 54
Published: 21 August 2018
10.1159/000489528
EISBN: 978-3-318-06385-1
... Abstract Drug substances used in the treatment of skin diseases have to reach target cells in the skin in order to exert a clinical effect. This makes topical treatment of skin diseases attractive because local drug delivery gives a more direct access to the target cells and reduces potential...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 6
Published: 26 April 2018
10.1159/000485069
EISBN: 978-3-318-06313-4
.... Furthermore, shockwave has been shown to temporarily increase tissue permeability through micro- and submicrosized deformations lasting for nanosecond to a micro second time scale, which can facilitate to deliver macromolecules or drug into cells without cytotoxicity. Recently, there has been a lot...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 33
Published: 22 January 2018
10.1159/000481108
EISBN: 978-3-318-06202-1
...-clinical models and clinical trials. In this chapter we discuss past and present research investigating the potential of direct drug delivery to the brain for the treatment of PD and other movement disorders. Introduction Therapeutic strategies aimed at delivering neurotrophic factors directly...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 41
Published: 06 December 2017
10.1159/000475697
EISBN: 978-3-318-05859-8
... by.” In its original use, the word was not associated with substance use behavior. Only later was the word associated with excessive alcohol consumption or with drug use. However, since several years, a growing group of authors also consider non-drug-related behaviors as being addictive in nature [ 1...