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Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
EISBN: 978-3-8055-9596-4
... Abstract High-through put technologies in evitably produce vast quantities of data. This presents challenges in terms of developing effective analysis methods, particularly where the analysis involves combining data derived from different experimental technologies. In this investigation...
Book Chapter
Book Chapter
Published: 05 August 1985
EISBN: 978-3-318-04935-0
... Abstract SummaryThe data for each participant in a clinical trial should be recorded on a form specially prepared for this purpose. Care should be taken to include all the information necessary to answer the questions asked in the protocol but the record form should not be cluttered up...
Book Chapter
Book Chapter
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 93
Published: 26 February 2020
EISBN: 978-3-318-06649-4
... Abstract Food composition tables and databases (FCT/FCDB) centralize data on the energy and nutrient content of foods of a certain country or region. They are essential for many activities related to nutrition. The main factors that can affect the quality of FCT/FCDB are the sources of the data...
Book Chapter
Series: Contributions to Nephrology
Volume: 197
Published: 08 April 2019
EISBN: 978-3-318-06477-3
... Abstract Remote monitoring of dialysis offers significant clinical benefits to patients and healthcare providers. However, the collection, transfer, and storage of large amounts of health data involved in remote monitoring require a careful consideration of privacy and data security concerns...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 91
Published: 13 March 2019
EISBN: 978-3-318-06403-2
... Abstract The FITS (Feeding Infants and Toddlers Study) and KNHS (Kids Nutrition and Health Study) are large-scale cross-sectional surveys designed to explore eating patterns, nutrient intakes, and food sources of nutrients among infants and children. FITS and KNHS use data from national surveys...
Book Chapter
Series: Contributions to Nephrology
Volume: 193
Published: 08 February 2018
EISBN: 978-3-318-06311-0
... patients susceptible to AKI. Concomitantly, there have been substantial advances in “big data” technologies in medicine, including electronic health records (EHR), data registries and repositories, and data management and analytic methodologies. EHRs are increasingly being adopted, clinical informatics...
Book Chapter
Series: Current Problems in Dermatology
Volume: 53
Published: 13 November 2017
EISBN: 978-3-318-06101-7
... Abstract Physicians rely on safety and efficacy data from pivotal trials to guide treatment decisions and manage patients. Even with robust clinical trial data, there remain questions regarding rare safety events and generalizability. Registries complement clinical trials. By evaluating...
Book Chapter
Series: Developments in Ophthalmology
Volume: 60
Published: 24 April 2017
EISBN: 978-3-318-06042-3
... corresponds to 387 million patients [ 1 ]. The number of people with diabetes worldwide has more than doubled during the past 20 years. Epidemiological data predict an inexorable and unsustainable increase in global health expenditure attributable to diabetes, so disease prevention should be given high...
Book Chapter
Series: Contributions to Nephrology
Volume: 187
Published: 12 February 2016
EISBN: 978-3-318-05826-0
... generations Although the appropriate use of EHRs improves quality of care, poorly designed EHRs could result in harm and unintended consequences, such as increased work tasks associated with computerized order entry; fragmentation of data; loss of communication; and clinical decision support, which may...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 34
Published: 09 July 2015
EISBN: 978-3-318-05474-3
... and efficacy data from the originator to the biosimilar, making it unnecessary to supply full documentation for the biosimilar. Due to the often extremely complicated structure of most biologics, biosimilarity can only be declared if careful physicochemical testing, in vitro and in vivo studies of biological...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 18
Published: 17 November 2014
EISBN: 978-3-318-02736-5
... analysis (e.g., LC-MS or electrophoresis) may further facilitate pharmacokinetic studies in neonates by overcoming some of the practical limitations. Pharmacokinetic Data Analysis In a pharmacokinetic data analysis, the drug concentrations measured in blood or serum at various time intervals after...
Book Chapter
Series: Key Issues in Mental Health
Volume: 178
Published: 01 February 2013
EISBN: 978-3-8055-9989-4
... Abstract Data from a number of different data sources can illustrate the magnitude and nature of violence against women. Some European countries have access to nationwide register data that complement the information obtained by surveys. Danish data on intimate partner violence (IPV...
Book Chapter
Published: 04 April 2011
EISBN: 978-3-8055-9685-5
Book Chapter
Book Chapter
Series: Frontiers of Hormone Research
Volume: 38
Published: 07 July 2010
EISBN: 978-3-8055-9445-5
... Abstract The GH receptor antagonist pegvisomant is an efficient agent to achieve biochemical control of acromegaly in those cases refractory to surgery and medical therapy with somatostatin analogs. We conducted an observational multicenter study consisting of data collection in accordance...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 38
Published: 07 July 2010
EISBN: 978-3-8055-9445-5
... of standardization, susceptibility to interference from IGF-binding proteins (IGFBP), lack of a pure international reference preparation, and the need for appropriate age-adjusted normative data. Current commercially available immunoassays differ in terms of assay principle (competitive vs. noncompetitive), assay...
Book Chapter