... Abstract Endogenous Cushing syndrome (CS) is caused by excess adrenal glucocorticoid secretion that is adrenocorticotropin(ACTH)-dependent or independent; ACTH-independent adrenocortical causes of CS account forup to 20% of CS in adults, and 15% in children over age 7 years. In younger children...

... Abstract The distinction between Cushing's syndrome and pseudo-Cushing is a major clinical challenge. Indeed, any endocrinologist used to dealing with Cushing's syndrome has certainly faced this dilemma more than once and is aware that there are no clear-cut solutions. Several factors...

... Abstract Cushing disease which is caused by the excessive production of ACTH is a rare andcomplex endocrine disorder that still represents a major challenge for the physician in termsof accurate diagnosis and efficient treatment. Diagnosing Cushing syndrome and its etiologyis an elaborate...

... Abstract Although polycystic ovary syndrome (PCOS) is the most common androgen excess disorder, screening for Cushing’s Syndrome (CS) should be considered in women with PCOS phenotype, particularly if they are also affected by other disturbances that increase their pretest probability (e.g...

... Abstract Cushing's syndrome (CS), including visceral obesity, dyslipidemia, hypertension and diabetes among its many manifestations, is “a model” of metabolic syndrome. Glucocorticoid (GC) excess, through a combination of effects on liver, muscle, adipose tissue and pancreas, increases...

... Abstract The diagnosis of Cushing's syndrome is challenging to endocrinologists as patients often present with an insidious history, together with subtle external clinical features. Moreover, complications of endogenous hypercortisolism, such as visceral obesity, diabetes, hypertension...

... vertical. Int J Pediatr Otorhinolaryngol 2015;79:2094-2098. 21. Bruininks R, Bruininks B: BOT-2 Bruininks-Oseretsky Test of Motor Proficiency, ed 2. Circle Pines, AGS Publishing, 2005. 22. Oyewumi M, Wolter NE, Heon E, Gordon KA, Papsin BC, Cushing SL: Using balance function to screen...

... Abstract Cushing’s disease (CD) is rare in the paediatric age range, but presents a diagnostic and therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues...

... student attitudes about mental illness: does medical-school education reduce stigma? Acad Psychiatry 2012;36:197-204. 26. Cushing AM, Jones A: Evaluation of a breaking bad news course for medical students. Med Educ 1995;29:430-435. 27. Deegan P: Hearing Voices Curriculum: Complete Training...

... Abstract The goals of ideal medical therapy for Cushing’s disease should be to target the aetiology of the disorder, and thus surgery is the current ‘gold standard’ treatment. However, no effective drug that directly and effectively targets the adrenocorticotropin-secreting pituitary adenoma...

... Abstract We evaluate the current role of microsurgery for Cushing’s disease (CD) and the efficacyof adjuvant treatment modalities. The standard treatment for primary CD remains transsphenoidalsurgery followed by adjuvant therapy in cases with persisting hypercortisolism.Moderately severe cases...