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Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350385
EISBN: 978-3-318-02404-3
... Abstract According to the biopsychosocial model, psychosocial and biological factors interact in a number of ways influencing onset and course of medical disease. In a longitudinal perspective, such factors may elicit different effects on health depending on their accumulation mechanisms...
Book Chapter
Book
Book Cover Image
Series: Nestlé Nutrition Institute Workshop Series
Volume: 98
Published: 21 March 2024
10.1159/isbn.978-3-318-07263-1
EISBN: 978-3-318-07263-1
Book Chapter
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 40
Published: 12 December 2016
10.1159/000448304
EISBN: 978-3-318-02759-4
... Abstract Increasing our knowledge about intracranial atherosclerosis (ICAS) natural history and prognostic factors is essential to improve its preventive therapy and thus reduce the dramatic clinical consequences caused by this entity. ICAS is characterized by a chronic and progressive course...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 39
Published: 03 August 2016
10.1159/000445417
EISBN: 978-3-318-05865-9
... or their epilepsy may have been on an unfavorable course at entry. Investment in the development of new compounds for epilepsy is not favored by the use of entrenched, largely patient-irrelevant outcome measures such as the 50% seizure reduction versus baseline, by the use of placebo controls, or by noninferiority...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350007
EISBN: 978-3-318-02404-3
... Abstract Social and behavioral scientists have long been interested in cumulative, life course processes. This chapter reviews prototypical questions and methods from the life span approach in psychology as well as the life course approach in sociology. Their relevance for understanding...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350747
EISBN: 978-3-318-02404-3
... Abstract Approaching (chronic) diseases within a ‘life course' framework provides primarily answers to two main questions: What are the long-term effects on health of life events and of previous exposures to risk (or protecting) factors during sensitive periods (e.g. childhood, adolescence...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350781
EISBN: 978-3-318-02404-3
... Abstract The concepts of cumulative life course impairment (CLCI) and health-related quality of life (QoL) are analyzed, in order to find shared and divergent aspects. The concept of QoL includes the patients' perception of their health and their personal experiences concerning the psychosocial...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350389
EISBN: 978-3-318-02404-3
..., life goals concepts and what constitutes a long-term impact, essential background to this area. We also describe the relationship of the concept of MLCD with the concept of cumulative life course impairment. Chronic disease has long-term impact on patients' lives, particularly by influencing MLCDs...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350783
EISBN: 978-3-318-02404-3
... Abstract In order to give a practical meaning to a concept, it is necessary to measure it. In this chapter, some guidelines for the creation of a life course questionnaire are given, starting from the concept of measurement and all the properties (validity, reliability, responsiveness...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350555
EISBN: 978-3-318-02404-3
... Abstract Cumulative life course impairment (CLCI) is a multidimensional construct, which reflects the overall increasing burden posed on patients by chronic (dermatological) disease. As such, CLCI can, to date, neither be directly measured nor can the patients' risk for CLCI be assessed...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350008
EISBN: 978-3-318-02404-3
... Abstract Psoriasis is a disease state that may present significant cumulative life course impairment (CLCI). The impact of psoriasis on CLCI can be divided into social factors such as stigmatization, psychological factors such as depression, and physical factors such as pruritis, pain...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350009
EISBN: 978-3-318-02404-3
... affected members of the same kindred who carry identical gene mutations, the overall clinical severity, course, and natural history for most are still usually predictable, based on their subtype [ 3 ]. For example, patients with localized EB simplex (formerly referred to as the Weber-Cockayne variant...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350010
EISBN: 978-3-318-02404-3
... Abstract Vitiligo is an acquired, idiopathic skin disease characterized by the mostly progressive loss of the inherited skin color leading to white patches and in some cases to total depigmentation. The course of this ancient disease is still unknown. The worldwide prevalence range is 0.5-1...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350055
EISBN: 978-3-318-02404-3
... of cumulative life course impairment (CLCI) in skin cancer patients has been carried out, a few studies suggest that skin cancer may strongly impair quality of life and eventually determine a significant CLCI (melanoma more than nonmelanoma skin cancer). Obviously, the life course of patients with melanoma...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350789
EISBN: 978-3-318-02404-3
... and the even longer-lasting comorbidity, chronic wounds can be associated with marked cumulative life course impairments. It is thus essential to detect any early signs of wound disease and psychosocial burden in patients at risk of chronic wounds. Though specific instruments have not yet been developed...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350056
EISBN: 978-3-318-02404-3
... Abstract Skin diseases are visible, and identifying abnormal skin generally does not require specialist knowledge. Dermatology is therefore a ripe field for studies of cumulative life course impairment, because of the many diseases that affect not only the patients, but also their psychosocial...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350178
EISBN: 978-3-318-02404-3
... Abstract Life course epidemiology is very important in the evaluation of chronic diseases and their long term physical, psychological, cognitive and social consequences. However, chronic dermatologic diseases can have a different impact on quality of life depending on patients' cultures...
Book
Book Cover Image
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/isbn.978-3-318-02404-3
EISBN: 978-3-318-02404-3