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Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324261
EISBN: 978-3-8055-9721-0
... Abstract Corneal dystrophies are bilateral, progressive, genetically determined noninflammatory diseases restricted to the cornea. These are characterized by deposition of nonnative protein or other material, both intracellular and extracellular, within the corneal layers. Dystrophies...
Book Chapter
Book Chapter
Book Chapter
Series: Developments in Ophthalmology
Volume: 61
Published: 27 May 2021
10.1159/000511821
EISBN: 978-3-318-06854-2
... Abstract Integrated intraoperative anterior segment optical coherence tomography is an extremely valuable tool that can be used by corneal surgeons when performing pediatric lamellar corneal transplant surgery. This chapter will demonstrate its use in infants and children with a variety...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 21 August 2017
10.1159/000475958
EISBN: 978-3-318-06085-0
... and have no visual complaints [ 14 ]. Light sensitivity (in the absence of corneal lesions) or dimming of colours should also alert the clinician to the possibility of DON. Orbital ache, gaze-evoked pain as well as gaze-evoked visual obscuration are not specific but should alert the clinician particularly...
Book Chapter
Book: Cornea
Series: ESASO Course Series
Volume: 6
Published: 11 August 2015
10.1159/000381492
EISBN: 978-3-318-05453-8
... Abstract Corneal collagen crosslinking (CXL) is usually practiced on keratoconic corneas to strengthen the corneal biomechanical structure. The conventional CXL procedure, with riboflavin and ultraviolet A (UVA), initially involves corneal de-epithelialization to allow riboflavin penetration...
Book Chapter
Book: Cornea
Series: ESASO Course Series
Volume: 6
Published: 11 August 2015
10.1159/000381494
EISBN: 978-3-318-05453-8
... Abstract This chapter focuses on endeavors to perform keratoplasties to treat eyes in high-risk settings and discusses alternative approaches (such as lamellar strategies). The historical and molecular backgrounds (histocompatibility antigens) as well as associated risk factors (corneal...
Book Chapter
Book: Cataract
Series: ESASO Course Series
Volume: 3
Published: 03 September 2013
10.1159/000350913
EISBN: 978-3-318-02411-1
... Abstract Lamellar corneal surgery for the correction of refractive errors has been evolving for more than 60 years. LASIK (laser-assisted in situ keratomileusis) is a well-known procedure for correction of different refractive defects as myopia, hyperopia and astigmatism. It is the most widely...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324074
EISBN: 978-3-8055-9721-0
... Abstract The International Committee for Classification of Corneal Dystrophies (IC3D) has provided an update of our knowledge on corneal dystrophies. This chapter gives the summary of clinical findings, onset, course, genetics, nosology, light and electron microscopy as well...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324075
EISBN: 978-3-8055-9721-0
... Abstract The International Committee for Classification of Corneal Dystrophies, briefly IC3D, was founded to develop a new, internationally accepted classification of corneal dystrophies (CDs) based on modern clinical, histological and genetical knowledge. Being members of the IC3D, the authors...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324077
EISBN: 978-3-8055-9721-0
... Abstract Several comprehensive reviews have been written recently that summarize what is currently known about the molecular genetic basis of the corneal dystrophies. The one that is the current definitive reference on the subject is the IC3D classification of the corneal dystrophies, written...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324078
EISBN: 978-3-8055-9721-0
... Abstract Schnyder corneal dystrophy (SCD) is a rare corneal dystrophy characterized by abnormally increased deposition of cholesterol and phospholipids in the cornea leading to progressive vision loss. SCD is inherited as an autosomal dominant trait with high penetrance and has been mapped...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324079
EISBN: 978-3-8055-9721-0
... Abstract Gelatinous drop-like corneal dystrophy (GDLD) was first reported in 1914 as a peculiar corneal dystrophy with an autosomal recessive inheritance mode. GDLD is rare in many countries, but relatively prevalent in Japan. The typical finding of GDLD is grayish, mulberry-like, protruding...
Book Chapter
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/000324081
EISBN: 978-3-8055-9721-0
... Abstract Corneal dystrophies typically result in a gradual bilateral loss of vision in a primary ‘white eye’ – often in conjunction with epithelial defects in later stages. Treatment of corneal dystrophies needs to be stage-related. To ensure a stage-related therapeutic approach, an adequate...
Book
Book Cover Image
Series: Developments in Ophthalmology
Volume: 48
Published: 20 April 2011
10.1159/isbn.978-3-8055-9721-0
EISBN: 978-3-8055-9721-0
Book Chapter
Book Chapter
Series: Developments in Ophthalmology
Volume: 43
Published: 08 June 2009
10.1159/000223833
EISBN: 978-3-8055-9125-6
... Abstract Corneal transplantation was conceptualized at the end of the 18th century, but it took more than 100 years before human corneal grafting was introduced. The greatest step forward was the demonstration by Filatov that corneal tissue can be collected and used post mortem. The history...
Book Chapter
Series: Developments in Ophthalmology
Volume: 43
Published: 08 June 2009
10.1159/000223837
EISBN: 978-3-8055-9125-6
...–5weeks. The storage phase is followed by a generally much shorter phase of 1–7 days, to reverse the corneal swelling occurring in the first phase and to transport the tissue to the clinic. Selection of the corneas based on inspection of the endothelium after storage as well as microbiological testing...
Book Chapter
Series: Developments in Ophthalmology
Volume: 43
Published: 08 June 2009
10.1159/000223839
EISBN: 978-3-8055-9125-6
... Abstract Currently, cryopreservation is the only method that offers the prospect of truly long-term storage of living cells and tissues. Despite some successful cryopreserved corneal grafts, freezing has been shown to damage the endothelium. When isolated cells are frozen, there are two...
Book Chapter
Series: Developments in Ophthalmology
Volume: 41
Published: 23 May 2008
10.1159/000131087
EISBN: 978-3-8055-8377-0
... Abstract Purpose: To demonstrate surgical treatment options for complications of severeforms of dry eye at the cornea, limbus and conjunctiva. Methods: Corneal, limbal andconjunctival surgical treatment strategies are outlined. Results: Amniotic membranetransplantation, different forms...