...Introduction Epidemiology Asthma and chronic obstructive pulmonary disease (COPD) are obstructive lung diseases that are common throughout the world ( 1 , 2 ). Both diseases are part of major global epidemics, which are increasing in incidence particularly in developing countries ( 3 , 4...

...The targets Frequently developed after years of smoking, chronic obstructive pulmonary disease (COPD) is characterized by progressive air outflow limitation that is not fully reversible ( 1 , 2 ). Recent estimates suggest that COPD affects as many as 10% of adults over the age of 40 worldwide...

... Abstract Exacerbations are important events in patients with asthma and chronic obstructive pulmonarydisease (COPD). Reducing the number, frequency and the severity of exacerbations istherefore an important management goal identified by treatment guidelines for both diseases.There...

... Abstract Chronic obstructive pulmonary disease (COPD) exacerbations are common events thatpunctuate the natural history of COPD contributing to disease severity progression and being themajor cause of COPD-related morbidity and mortality. Currently available pharmacologicalstrategies are only...

... Abstract Pulmonary hypertension (PH) is a common complication of advanced chronic obstructive pulmonary disease (COPD) and its presence is associated with decreased survival. Owing to its frequency, COPD is by far the most common cause of PH. PH is consecutive to the elevation of pulmonary...

... Abstract Respiratory disorders are among the most frequent causes of death and severe disability from the steadily worsening global pandemic of smoking tobacco. Two disorders stand out: lung cancer and chronic obstructive pulmonary disease (COPD). First, lung cancer caused 1.59 million deaths...

...Indacaterol: A new once-daily long-acting β₂-adrenoceptor agonist (LABA) Introduction An important step in simplifying the management of chronic airway diseases like chronic obstructive pulmonary disease (COPD), and improving the adherence with prescribed therapy is the attempt...

... Abstract In chronic inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), changes in bronchial microvasculature are present and contribute to airway wall remodeling. Angiogenesis and vascular leak seem to be prevalent in asthma, while vasodilatation...

... obstructive pulmonary disease (COPD) exacerbations in current and former smokers. The realization that NTHI causes serious infections in humans has generated interest in the study of the pathogenesis associated with this bacterium and also stimulated considerable efforts towards the evaluation of candidate...