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Series: Monographs in Oral Science
Volume: 27
Published: 24 September 2018
10.1159/000487840
EISBN: 978-3-318-06369-1
... Abstract This chapter aims to discuss the way dental practitioners manage deep carious lesions (DCL) in routine practice and the barriers and incentives/facilitators to changes in accepted practice. In concert with the philosophy of minimal intervention dentistry, the concept of quaternary...
Book Chapter
Series: Endocrine Development
Volume: 32
Published: 21 August 2017
10.1159/000475728
EISBN: 978-3-318-05974-8
... mucosa [ 2 ] contained another messenger (“gastric secretin” - abbreviated gastrin). Hence, the first discovery of blood-borne “chemical messengers” was of gastrointestinal origin, and the very concept of endocrinology can be said to be born in the gut. Subsequently, Starling introduced the word hormone...
Book Chapter
Series: Contributions to Nephrology
Volume: 189
Published: 22 December 2016
10.1159/000451043
EISBN: 978-3-318-05929-8
... and experimental efforts have been made to try and understand them. Moreover, water interactions have been recognized as fundamental for the blood response to contact with polymers. Summary: We have proposed the ‘intermediate water' concept and hypothesized that intermediate water, which prevents the proteins...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 33
Published: 14 October 2013
10.1159/000351888
EISBN: 978-3-318-02459-3
... syndrome in the central nervous system. We proposed a new concept termed acute cerebrovascular syndrome (ACVS), which includes TIA in acute settings and AIS. The concept of ACVS is comparable to acute coronary syndrome (ACS), which includes unstable angina and acute myocardial infarction. When a focal...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350389
EISBN: 978-3-318-02404-3
... major life-changing decisions (MLCDs). Understanding of the impact on MLCDs is largely missing from health outcomes research. It is potentially important in the assessment of the overall burden and cumulative impact of chronic disease. This chapter reviews the concepts of life events, life transition...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 30
Published: 22 June 2012
10.1159/000338742
EISBN: 978-3-318-02184-4
... Abstract Andre Robert’s concept of ‘gastric cytoprotection’ was based on wrong premises (in part because of the initial lack of histologic evaluation). It, nevertheless, stimulated extensive research that led to better understanding of cell/tissue injury, discovery of new pathways...
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Series: Advances in Biological Psychiatry
Volume: 28
Published: 23 April 2012
10.1159/isbn.978-3-8055-9803-3
EISBN: 978-3-8055-9803-3
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Book Chapter
Series: Monographs in Human Genetics
Volume: 19
Published: 07 March 2011
10.1159/000318427
EISBN: 978-3-8055-9595-7
... or sporadic occurrence. This highly variable expressivity together with the more severe manifestation of CFNS in females than in males provoked the formulation of a novel pathological mechanism: the concept of cellular interference. This concept proposes divergent cellular behavior in heterozygous females...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 27
Published: 17 November 2010
10.1159/000319504
EISBN: 978-3-8055-9606-0
... depression, there is a relationship between the severity and duration of the disorder and the increased frequency of heart disease, type 2 diabetes, various autoimmune diseases, arthritis and cancer [ 2 ]. The concept of a disordered immune system playing a major role in the mental state can be traced...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 100
Published: 12 August 2009
10.1159/000235716
EISBN: 978-3-8055-9225-3
...The Columbus Concept and the Science Essential vs. Nonessential Fatty Acid Components Among dietary lipids (triglycerides, phospholipids, cholesterol – CHL) and their fatty acid constituents (saturated, monounsaturated, polyunsaturated), the only essential component to mankind...
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Series: Frontiers of Neurology and Neuroscience
Volume: 24
Published: 12 February 2009
10.1159/000197880
EISBN: 978-3-8055-9016-7
... Abstract Subtle cognitive impairments without dementia are common in the elderly population and numerousnosological entities have been proposed for their classification. The concept of mild cognitiveimpairment has become increasingly popular both in clinical practice and in research. It has...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 24
Published: 12 February 2009
10.1159/000197886
EISBN: 978-3-8055-9016-7
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Book Chapter
Series: Chemical Immunology and Allergy
Volume: 94
Published: 10 September 2008
10.1159/000154844
EISBN: 978-3-8055-8629-0
... Abstract Allergic reactions are caused by harmless allergens, which are recognized by the specific immune system. Allergen-specific T cells are assumed to play a key role in the sensitization phase and in immunological memory. Current immunological concepts suggest that asymptomatic T-cell...
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