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Book Chapter
Book Chapter
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 99
Published: 18 April 2024
EISBN: 978-3-318-07336-2
... milk. Recent studies have shown that the time of lactation, circadian rhythm, maternal diet, genetics, and even presence of maternal or infant infection can influence milk composition. Human milk, however, is not just a sum of single nutrients but a complex biofluid rich and organized in potentially...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
EISBN: 978-3-318-06341-7
... Abstract The evolution of lactation and the composition, structures, and functions of milk's biopolymers illustrates that the Darwinian pressure on lactation selected for gene products with considerable structural complexity and diverse functions within the digestive system. For example...
Book Chapter
Book Chapter
Series: Fast Facts Collection 2017
Published: 19 June 2017
EISBN: 978-1-910797-48-8
Book Chapter
Series: Medicine and Sport Science
Volume: 61
Published: 16 June 2016
EISBN: 978-3-318-03011-2
... and recovery time. The relative contribution of common DNA variants and of rare DNA variants to a human trait is termed the ‘genetic architecture' of the trait (table 1 ) [ 4 ]. Though many rare genetic diseases have a single gene as their major determinant, complex non-disease phenotypes are most likely...
Book Chapter
Series: Developments in Ophthalmology
Volume: 57
Published: 04 April 2016
EISBN: 978-3-318-05820-8
... Abstract This chapter describes the techniques and pitfalls that the reader may come across when dealing with complex pediatric cataract cases. Each eye in these circumstances is unique, and the examples and general advice shared are intended to help the reader develop a plan for surgery...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 84
Published: 18 January 2016
EISBN: 978-3-318-05599-3
... contribute to the heterogeneity in physiologies observed in human studies. The risk factors determined for populations (i.e. the population-attributable risk) cannot be applied to the individual. Developing individual risk/benefit factors in light of the genetic diversity of human populations, the complexity...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
EISBN: 978-3-318-02789-1
... is associated with complex neurological dysfunctions. Here, we review the clinical phenotype and genetic defects linked to such syndromic CHH. This analysis highlights the close link between the ubiquitin pathway, synaptic proteins and CHH, as well as unexpected mutations in genes encoding nucleolar proteins...
Book Chapter
Series: ESASO Course Series
Volume: 4
Published: 27 February 2014
EISBN: 978-3-318-02564-4
... cell complex (GCC) thickness and its possible correlation with visual recovery after vitreoretinal surgery for idiopathic ERM. We analyzed best-corrected visual acuity, mean macular thickness and mean GCC thickness 1 day before surgery, and 7 and 180 days after surgery. Internal segment/outer segment...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 105
Published: 01 October 2012
EISBN: 978-3-318-02228-5
... of acute illness, and multiple interventions. Therefore, a new way of approaching the complexity of these patients is required, progressing from the whole body to compartments, organs, pericellular space, and cellular metabolism. We propose to untangle the complexity of intensive care unit patients...
Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
EISBN: 978-3-8055-9811-8
... the primary failing organ can be either the heart or the kidneys [ 3 ]. Such classification has been endorsed and further developed by the ADQI (Acute Dialysis Quality Initiative) consensus group leading to a comprehensive characterization of the complex heart-kidney organ crosstalk [ 4 ]. This new...
Book Chapter
Book Chapter
Book Chapter
Book: Meiosis
Series: Genome Dynamics
Volume: 5
Published: 28 October 2008
EISBN: 978-3-8055-8968-0
... Abstract During the first meiotic cell division (meiosis I), homologous chromosomes pair, synapse, recombine, andsegregate, using highly coordinated and tightly regulated mechanisms. The synaptonemal complex (SC),a proteinaceous tripartite structure, plays an important role both as a scaffold...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
EISBN: 978-3-8055-9596-4
... Abstract The association between genetic markers and serological major histocompatibility complex (MHC) definition was studied in experimental White Leghorn lines selected for different immune traits. Different markers, three variable number tandem repeats (VNTRs) and 10 single nucleotide...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 157
Published: 25 May 2007
EISBN: 978-3-318-01467-9
... region. The biological effects of IC are primarily related to their molecularsize and composition: when added to a culture of human mesangial cells, large ICexhibit a proliferative effect while small complexes are inhibitory. These activities have beenobserved using IC obtained from sera of IgAN patients...