.... There is now an abundant cache of data signifying immune system activation as an impetus in the pathogenesis of this devastating condition. Furthermore, recent rigorous investigations have revealed multiple inciting factors, including several important complement-activating components, thus creating a new...

... Abstract Complement is vital for protecting individuals against pathogens and any disturbance of homeostasis associatedwith appearance of foreign antigens. Four antenna molecules seek for putative danger and subsequentlystart three activation pathways to eliminate the hostile triggering signal...

... Abstract The complement system is a major component of innate immunity. During an inflammatoryreaction, the eye is potentially threatened by homologous complement attack, andunregulated complement activation could lead to tissue damage and vision loss. The complementsystem is continuously...

... Abstract The complement system is regarded as an ancient host defense mechanism that helps topromote phagocytosis and/or killing of foreign microorganisms. Less well known is the facilitatoryrole that complement and other closely related molecules of the innate immune systemplay in the removal...

... present in the maternal blood that circulates in the intervillous space and inthe decidual vessels. This review deals with the role played by the complement system at theplacental level both in physiological and pathological conditions of pregnancies. Complementcomponents found in the placental tissue...