... Abstract The collagenous C-type lectin family (collectins) members are humoral moleculesfound in the serum and on certain mucosal surfaces. In humans the family of collectinsinclude the mannose-binding lectin, surfactant protein A and surfactant protein D. Theydemonstrate broad ligand...

...-binding proteins (lectins). Cell-surface C-type lectin receptors (CLRs), such as DCSIGN,L-SIGN, the mannose receptor, macrophage galactose binding lectin, and otherlectins, such as the soluble collectins and galectin-3, recognize particular glycan Ags ofschistosomes and allergens, which may contribute...

... to the Innate Immunity Homeostatic defenses of the middle ear and Eustachian tube are maintained in part by molecules related to the innate immunity, mucins, surface active substances, and aqua- porins. The molecules related to the innate immunity are lysozyme, lactoferrin, defensin, collectin, Toll-like...

... of the complement system have an important role in opsonization and removal of microbial antigens and dead cell and tissue fragments. In this process, complement components can be activated by antibodies, by serum proteins of the collectin family and by microbial surface glycoproteins and extracellular matrix...

... by increasing mucosal permeability. Der p 1 and Der f 1 also cleave SP-A and SP-D lung collectins which have protective roles in allergy. The cleavage and consequent inactivation of SP-A and SP-D may be a novel mechanism to account for the potent allergenicity of Der p 1 and Der f 1 [ 24 ]. Due to its high...

.... Carbohydrate ligands derived from a wide variety of pathogens, such as viruses, bacteria and fungi form the main core of ligands recognised by CLRs. There are four groups of CLRs based on their structural features: type I (mannose receptors), type II, collectins and NK cell receptors (type V). They react upon...