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Book Chapter
Book Chapter
Book Chapter
Series: Monographs in Human Genetics
Volume: 18
Published: 15 February 2010
10.1159/000287601
EISBN: 978-3-8055-9281-9
... Abstract Genome wide array comparative genomic hybridization has revolutionized the analysis of genomes, not only in exposing copy number variants (CNVs) leading to mental retardation and developmental disorders but also in revealing the extent of the genome that is copy number variable...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442782
EISBN: 978-3-318-05830-7
... Abstract Aims: Study the choroidal neovascularization (CNV) morphological evolution after treatment using optical coherence tomography angiography (OCTA). Method: We used Optovue XR Avanti, with split-spectrum amplitude-decorrelation angiography algorithm. Results: OCT Angiography...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431194
EISBN: 978-3-318-05565-8
... Abstract Choroidal neovascularization (CNV) is a significant cause of vision loss in all age groups. The most common cause of CNV is age-related macular degeneration (AMD). However, CNV can also occur as a secondary manifestation of various inherited and acquired conditions, including...
Book Chapter
Series: ESASO Course Series
Volume: 4
Published: 27 February 2014
10.1159/000355969
EISBN: 978-3-318-02564-4
... Abstract Choroidal neovascularization (CNV) is one of the most important vision-threatening complications of degenerative myopia, occurring in up to 10% of highly myopic eyes. Optical coherence tomography (OCT) is a noninvasive examination technique, easy to be performed, and well accepted...
Book Chapter
Series: ESASO Course Series
Volume: 11
Published: 28 December 2020
10.1159/000485309
EISBN: 978-3-318-06643-2
... Abstract Optical coherence tomography angiography (OCTA) has significantly expanded our knowledge on age-related macular degeneration (AMD) and associated choroidal neovascularization (CNV). The aim of this review is to provide insights into exudative AMD through a recap of OCTA studies...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442800
EISBN: 978-3-318-05830-7
... Abstract Purpose: To analyze the ability of optical coherence tomography angiography (OCT-A) to detect the presence of myopic choroidal neovascularization (CNV) and to describe structural features of myopic CNV on OCT-A. Methods: Patients with CNV secondary to high myopia (>6...
Book Chapter
Series: ESASO Course Series
Volume: 4
Published: 27 February 2014
10.1159/000355967
EISBN: 978-3-318-02564-4
... Abstract The purpose of this study was to develop a method of segmentation using ‘en face' spectral domain-optical coherence tomography (SD-OCT) (‘en face' C-scans) to evaluate different patterns of the choroidal neovascular network (CNV) due to age-related macular degeneration (AMD...
Book Chapter
Book: Anti-VEGF
Series: Developments in Ophthalmology
Volume: 46
Published: 13 August 2010
10.1159/000320010
EISBN: 978-3-8055-9530-8
... Abstract Choroidal neovascularization (CNV) is the most common vision-threatening macular complication in pathologic myopia (PM) being detectable in 4–11% of the affected eyes. Treatment of PM-related CNV is still controversial. Intravitreal injections of antivascular endothelial growth factor...
Book Chapter
Series: ESASO Course Series
Volume: 9
Published: 07 June 2017
10.1159/000471824
EISBN: 978-3-318-06068-3
... the identification of various genetic and environmental factors involved in the development of AMD, some aspects of the pathophysiological mechanism remain unknown. Pathophysiology and Natural History Exudative AMD is characterized by choroidal neovascularization (CNV) that denotes the pathologic growth...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317165
EISBN: 978-3-8055-9596-4
... Abstract As a complement to the Bovine HapMap Consortium project, we initiated a systematic study of the copy number variation (CNV) within the same cattle population using array comparative genomic hybridization (array CGH). Oligonucleotide CGH arrays were designed and fabricated to cover all...
Book Chapter
Book: Anti-VEGF
Series: Developments in Ophthalmology
Volume: 46
Published: 13 August 2010
10.1159/000320011
EISBN: 978-3-8055-9530-8
... Abstract Macular edema (ME) and choroidal neovascularization (CNV) can complicate the course of several inflammatory chorioretinal diseases, leading to a severe visual function impairment. The most frequently involved clinical entities include for example multifocal choroiditis, presumed ocular...
Book Chapter
Series: Developments in Ophthalmology
Volume: 56
Published: 21 March 2016
10.1159/000442780
EISBN: 978-3-318-05830-7
... over 50 years of age in the developed world [ 1 ]. Choroidal neovascularization (CNV), the hallmark of neovascular AMD, only occurs in 10-15% of these patients but is responsible for more than 80% of cases of severe visual loss [ 2 , 3 ]. In these cases, abnormal blood vessels grow from...
Book Chapter
Series: Developments in Ophthalmology
Volume: 58
Published: 24 April 2017
10.1159/000455282
EISBN: 978-3-318-06033-1
... of macular edema. Their abnormal permeability and the inflammatory reaction are mechanisms involved in this accumulation of fluid, which occurs in all layers. Cystoid macular edema is more often associated with subepithelial occult choroidal neovascularization (CNV) than it is with pre-epithelial classic CNV...
Book Chapter
Series: ESASO Course Series
Volume: 10
Published: 23 May 2018
10.1159/000487412
EISBN: 978-3-318-06356-1
... of the angiographic examinations is used to identify any injuries like retinal vascular abnormalities or choroidal neovascularization (CNV). Optical coherence tomography angiography (OCT-A) is a new method to visualize the different retinal plexuses and choroidal plexus, and it is a dye-free, rapid, and three...
Book Chapter
Book: Anti-VEGF
Series: Developments in Ophthalmology
Volume: 46
Published: 13 August 2010
10.1159/000320013
EISBN: 978-3-8055-9530-8
... therapeuticregimen. Choroidal neovascularization (CNV) can rarely complicate the course of several chorioretinal dystrophies. Little is known regarding the natural history of this form of CNV. Visual acuity (VA) can be stable for a long time with a late evolution toward fibrosis and atrophy [ 1...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000438969
EISBN: 978-3-318-05565-8
... Abstract Age-related macular degeneration (AMD) is the leading cause of severe vision loss in individuals over the age of 50 years. Choroidal neovascularization (CNV) is the hallmark of ‘wet' or ‘exudative' AMD, and is responsible for approximately 90% of cases of severe vision loss due to AMD...
Book Chapter
Series: ESASO Course Series
Volume: 10
Published: 23 May 2018
10.1159/000487409
EISBN: 978-3-318-06356-1
... (PED), choroidal neovascularization (CNV), and geographic atrophy are the key features assessed for late AMD (Fig. 3 ). Detailed grading of early AMD features of drusen characteristics based on CFP, include drusen size (usually graded categorically as small <63 μm; ≥63 and <125 μm; ≥125...
Book Chapter
Series: Developments in Ophthalmology
Volume: 47
Published: 18 August 2010
10.1159/000320080
EISBN: 978-3-8055-9435-6
... of ME. Their abnormal permeability and the inflammatory reaction are mechanisms involved in this accumulation of fluid, which occurs in all layers. Cystoid ME is more often associated with subepithelial occult choroidal neovascularization (CNV) than it is with pre-epithelial classic CNV...