... reflects a clinical issue. Thus, we have devised a new index, the ‘clearance gap' (CL-Gap), which quantifies the difference between the effective clearance (eCL) of a hemodialysis (HD) patient and the theoretical clearance (tCL) of a dialyzer to detect a decrease in dialysis efficiency due to VA...

... Abstract Peritoneal dialysis adequacy is monitored primarily by indices of small solute clearance, Kt/V urea and creatinine clearance (C cr ). Once a threshold of adequacy has been obtained, however, increasing small solute clearance does not result in improved long-term outcomes of PD...

... clearance rates of any middle molecule across any haemodiafilter can be predicted from known or measurable factors such as its sieving coeffi -cient, bound fraction and molecular weight. The removal of middle molecules is alsoinfl uenced by factors within the patient. Β2-MG is distributed within...

... Abstract Apoptotic cells are swiftly engulfed by macrophages and immature dendritic cells.Inefficient clearance of apoptotic cells has been implicated as a cause of inflammation andautoimmune diseases. Milk fat globule-EGF factor 8 (MFG-E8) and developmental endotheliallocus-1 (Del-1...

... Abstract Systemic lupus erythematosus (SLE) is characterized by a diverse array of autoantibodies,particularly against nuclear antigens, thought to derive from apoptotic and necrotic cells.Impaired clearance functions for dying cells may explain accumulation of apoptotic cells inSLE tissues...