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Series: Contributions to Nephrology
Volume: 198
Published online: 16 April 2019
Published in print: 07 May 2019
10.1159/isbn.978-3-318-06424-7
EISBN: 978-3-318-06424-7
Book Chapter
Series: Contributions to Nephrology
Volume: 185
Published: 26 May 2015
10.1159/000380970
EISBN: 978-3-318-05465-1
... Abstract The sequential bone disorders, serum parameter abnormalities and vascular calcification that are associated with chronic kidney disease (CKD) have come to be generally known as CKD-mineral bone disorder (MBD). Klotho, a causative protein of aging, and fibroblast growth factor 23 (FGF23...
Book Chapter
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517749
EISBN: 978-3-318-06937-2
... Abstract Clinical Background: Although chronic kidney disease (CKD) and smoking are both associated with high rates of morbidity and mortality, the interplay between the two is not widely understood. Epidemiology: The incidence of CKD progression has been shown to be significantly...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517698
EISBN: 978-3-318-06937-2
... Abstract Chronic kidney disease (CKD) is strongly associated with the full spectrum of cerebrovascular disease including ischaemic and haemorrhagic stroke, small vessel disease, and vascular cognitive impairment. Shared conventional vascular risk factors such as age, hypertension, and diabetes...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517704
EISBN: 978-3-318-06937-2
... of the interrelationships between heart and kidney disease that are “cardiorenal syndrome (CRS)” and “chronic kidney disease (CKD) and coronary heart disease (CHD).” Challenges: For CRS, we discuss its epidemiology, types, pathophysiological mechanisms common to CRS types 1, 2, 3 and 4 and pathogenesis of CSR type 5...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517696
EISBN: 978-3-318-06937-2
... Abstract Clinical Background and Epidemiology: Low physical activity is a common phenotype in individuals living with chronic kidney disease (CKD). It increases as renal function declines and is associated with adverse clinical outcomes and a poor quality of life (QOL). Both behavioral...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000516715
EISBN: 978-3-318-06296-0
... Children with chronic kidney disease (CKD) have a mortality that is 30-times higher than age-matched, healthy children. There is also a high incidence of malnutrition and short stature. These factors are interlinked: short stature at the start of dialysis is associated with a 2-fold increased mortality...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517669
EISBN: 978-3-318-06937-2
... Abstract Clinical Background and Epidemiology: Nutrition and obesity are both important and common clinical issues in chronic kidney disease (CKD). Protein-energy wasting predicts adverse clinical outcomes in CKD. Obesity is associated with poor health outcomes. Nutrition management...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517670
EISBN: 978-3-318-06937-2
... Abstract Chronic kidney disease (CKD) is considered a public health problem and part of the growing burden of noncommunicable diseases. Many studies have searched for ways to reduce the risk of complications and death. One possible approach to modify the course of this disease is the adoption...
Book Chapter
Series: Contributions to Nephrology
Volume: 198
Published: 07 May 2019
10.1159/000496636
EISBN: 978-3-318-06424-7
... Abstract Background: The pathogenesis of anemia in chronic kidney disease (CKD) could be multifactorial. In recent animal studies, hepcidin knockout (KO) mice with adenine-induced CKD did not exhibit anemia and iron deficiency. Hepcidin has emerged as a major player in the development...
Book Chapter
Series: Contributions to Nephrology
Volume: 198
Published: 07 May 2019
10.1159/000496528
EISBN: 978-3-318-06424-7
... Abstract The results of previous large clinical trials have revealed that low hemoglobin (Hb) levels are significantly associated with adverse events (cardiovascular disease, infection, hospitalization, and mortality) in patients with chronic kidney disease (CKD). However, in the general...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445469
EISBN: 978-3-318-05884-0
... Abstract Chronic kidney disease (CKD) diagnosis and staging are based on estimated or calculated glomerular filtration rate (GFR), urinalysis and kidney structure at renal imaging techniques. Ultrasound (US) has a key role in evaluating both morphological changes (by means of B-Mode...
Book Chapter
Series: Contributions to Nephrology
Volume: 193
Published: 08 February 2018
10.1159/000484962
EISBN: 978-3-318-06311-0
... Abstract Background: Acute kidney injury (AKI), even if followed by renal recovery, is a risk factor for the future development of chronic kidney disease (CKD) and end-stage renal disease (ESRD). In the previous years, novel insights in the pathophysiology of CKD progression suggested...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517722
EISBN: 978-3-318-06937-2
... Abstract Clinical Background: Chronic kidney disease (CKD) is a condition that causes important limitations to patients’ lives. The limitations imposed as a result of the disease end up hampering the exercise of citizenship by individuals, including work and daily activities. Epidemiology...
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485694
EISBN: 978-3-318-06298-4
... Abstract Background: There is an increasing prevalence of dementia associated with population aging, and anti-dementia measures have now become of increasing importance in Japan. Chronic kidney disease (CKD) is a risk factor for cognitive impairment. Summary: We previously demonstrated...
Book Chapter
Series: Contributions to Nephrology
Volume: 192
Published: 08 February 2018
10.1159/000484277
EISBN: 978-3-318-06251-9
... Abstract Background: Chronic kidney disease (CKD) is a risk factor of cardiovascular disease (CVD) and end-stage renal disease (ESRD). Early detection and management of risk factors of incidence and progression of CKD are necessary. We have been studying these risk factors among community...
Book Chapter
Series: Contributions to Nephrology
Volume: 199
Published: 17 December 2021
10.1159/000517671
EISBN: 978-3-318-06937-2
... and acute. Examples include the marked influence of poverty on chronic kidney disease (CKD) in low-, middle- and high-income countries [ 1 ], wide variation in the burden of CKD and its underlying determinants across the world, with some countries and regions experiencing dramatic increases [ 2 , 3...