... Abstract In the sensory hair cells of the mammalian cochlea, the primary cilia in the planar cell polarity as well as the tight junctions in the epithelial cell polarity and the barrier are important to maintain normal hearing. Temperature-sensitive mouse cochlear precursor hair cells were used...

... Abstract Hereditary cystic kidney diseases are considered as “ciliopathies” caused by abnormalities of the “primary cilia” situated on the tubules. As a result of dysplasia and dysfunction of cilia, formation of cysts occurs at various stages of life. Although occurring at a low incidence...

..., Aygun MG, Hildebrandt F: Spectrum of clinical diseases caused by disorders of primary cilia. Proc Am Thorac Soc 2011;8:444-450. 5. Lin AE, Krikov S, Riehle-Colarusso T, et al: Laterality defects in the National Birth Defects Prevention Study (1998-2007): birth prevalence and descriptive epidemiology...

... by motile and sensory cilium function at the node. Monociliated cells at the node have motile cilia that exhibit clockwise rotation generating a leftward flow. Such flow is thought to impinge on cilia in the crown cells at the edge of the node, causing left-sided propagation of calcium signaling [ 11 , 12...

... Abstract In studying oviductal physiology, it is important to sort out the complex interrelationships between muscle, cilia, nerves and secretory processes as they each of themselves, or in concert, effect gamete transport. In this review, a variety of physiological techniques...

... on the role of bitter and sweet taste receptors in human airway innate immunity and their clinical relevance to rhinosinusitis. The bitter taste receptor T2R38 expressed in sinonasal cilia detects bitter bacterial quorum-sensing molecules and activates a nitric oxide-dependent innate immune response; moreover...

..., and the assembly and function of basal bodies and cilia have been suggested [ 15 ]. In particular, ALMS1 associates with the proximal ends of centrioles and basal bodies and is implicated in C-Nap1 and PCM1-related functions. Involvement of the ALMS motif-containing proteins C10orf90 and KIAA1731 in primary cilium...

... ribbons, microtubular sheaves, and cilia, is observed. Little is known about the genetics responsible for the development of PPTs. Several chromosomal abnormalities have been identified frequently in pineoblastomas and PPTIDs but less commonly in pineocytomas. Pineoblastomas are known to occur in patients...

... Abstract Odor transduction and quality coding involves a cascade of events that occur at the levelof the olfactory epithelium and olfactory bulbs. Odorants bind to one or a few specific olfactoryreceptors located in the cilia of olfactory neurons. These olfactory receptor proteins makeup...

... in scrambled siRNA infected cells or in uninfected cells in partially infected, mosaic epidermis [ 19 ]. In observing microtubule organization in the single-layered epithelium, Fuchs’ group noticed that cilia are present and apically oriented. Although sonic hedgehog (SHH) signaling occurs through cilia...

...-TBNA include benign and reactive bronchial epithelial cells, mucous, and cartilage. Bronchial epithelial cells have basally oriented nuclei, a columnar shape, and terminal bars with cilia. Clusters of bronchial epithelial cells can get stretched out by smearing and create cells with a stellate-shaped...

.... Antonini A, Siri C, Santangelo G, Cilia R, Poletti M, Canesi M, Caporali A, Mancini F, Pezzoli G, Ceravolo R, Bonuccelli U, Barone P: Impulsivity and compulsivity in drug-naive patients with Parkinson's disease. Mov Disord 2011;26:464-468 10. Cornelius JR, Tippmann-Peikert M, Slocumb NL, Frerichs CF...

... and somewhat hyperchromatic. Larger nucleoli can be seen in reactive or reparative conditions. The most characteristic feature of benign and reactive bronchial cells is the presence of cilia on the apical surface arising from a terminal bar. The cilia often stain metachromatically with Romanowsky-based stains...

... 22. Wang B, Li Y: Evidence for the direct involvement of βTrCP in Gli3 protein processing. Proc Natl Acad Sci USA 2006;103:33-38 23. Huangfu D, Anderson KV: Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci USA 2005;102:11325-11330 24. Huangfu D, Liu A, Rakeman AS, Murcia NS...

...-88. 30. Sen Gupta P, Prodromou NV, Chapple JP: Can faulty antennae increase adiposity? The link between cilia proteins and obesity. J Endocrinol 2009;203:327-336. 31. Shalata A, Ramirez MC, Desnick RJ, Priedigkeit N, Buettner C, Lindtner C, Mahroum M, Abdul-Ghani M, Dong F, Arar N, Camacho...

... was the most commonly isolated bacterium, especially in adenoid tissue and pathologic ethmoid mucosa ( fig. 1 ). Focusing our attention on mucosal alterations in 10 ethmoid samples in which bacterial biofilm were present, we found a marked destruction of the epithelium with a complete absence of cilia, while...

...References References 1. Bisceglia M, Galliani CA, Senger C, Stallone C, Sessa A: Renal cystic diseases: a review. Adv Anat Pathol 2006;13:26-56. 2. Barr MM: Caenorhabditis elegans as a model to study renal development and disease: sexy cilia. J Am Soc Nephrol 2005;16:305-312. 3...

... A: What are the most important nonmotor symptoms in patients with Parkinson’s disease and are we missing them?. Mov Disord 2010;25:2493-2500 17. Siri C, Cilia R, De Gaspari D, Villa F, Goldwurm S, Marco C, Pezzoli G, Antonini A: Psychiatric symptoms in Parkinson’s disease assessed with the SCL-90R...