... Recent cholesterol-lowering drug trials have been very disappointing for cholesterol experts and the cholesterol drug industry. Three events as important in terms of media coverage as of science and medicine are held each year around the issue of cholesterol: the annual meeting of the American...

... produce more anti-inflammatory cytokines, show a decreased lipid uptake, an increased cholesterol efflux, and a less foamy nature. Thus, bleeding processes within plaques do not necessarily lead to destabilization. They may also alter the macrophage response to a more stabilizing one over time if an acute...

... The ‘cholesterol hypothesis’ was established several decades ago, and has been accepted in medical fields worldwide. The hypothesis suggests that decreasing the intake of cholesterol and saturated fatty acids (animal fats) while increasing that of linoleic acid abundant in vegetable oils...

... cholesterol levels Table 1. Comparative serum cholesterol levels Serum Cholesterol Concentrations Because genes affecting lipid metabolism as well as cardiovascular structure and function are so alike across the entire mammalian class, it seems plausible that ‘normal’ serum cholesterol...

... The relationship between dietary and blood cholesterol has been a topic of debate for more than half a century. The concept of a direct relationship between the two is simplicity itself, yet as with many simplistic associations, not necessarily valid. As once noted by H.L. Menckin: ‘For every...

... types of ischemic heart disease has been decreasing over the past decades in Japan [ 3 ]. High blood cholesterol levels are a well-known risk factor for CHD. The majority of Japanese researchers believe that the lower the cholesterol level one has the better [ 4 ]. However, if all-cause mortality...

...% of the body mass, more than 50% of overall metabolism and only skeletal muscle activity can increase whole body metabolism 10-fold or greater, making the impact of caloric, fat and cholesterol intake on disease dependent, or at least interactive, with muscle activity. Skeletal muscle is the site...

... The idea that a high intake of saturated fat and a high cholesterol concentration in the blood lead to atherosclerosis and cardiovascular disease emanates from a variety of sources. When considered together, it is understandable that a whole world of doctors and medical scientists have...