... Abstract An estimated 2.9 million cases of Chlamydia trachomatis occur annually in the USA, and while most infections are not detected and reported, chlamydia is the most commonly reported nationally notifiable disease in the USA, with over 1.2 million cases reported in 2009. Rates...

... Abstract Disease pathogenesis due to Chlamydia trachomatis is a complicated process that involves: (1) exposure to the organism and infectivity; (2) survival within the host cell; (3) virulence associated with specific strain types; (4) innate and acquired immunity, and (5) host genetic...

... Abstract Next generation sequencing approaches have led to completion of several dozen chlamydial genome sequences, most of which are from Chlamydia trachomatis . Analysis of these genomes has shown that chlamydiae, like other obligate intracellular bacteria, have a much reduced genome...

... Abstract Screening tests to detect Chlamydia trachomatis infections have advanced to permit the detection of nucleic acids from organisms. The development of these molecular assays that can detect and amplify the specific nucleic acids from the genes of C. trachomatis are called nucleic...

... Abstract Treatment of patients with Chlamydia trachomatis infection prevents sexual transmission. Treatment of sexual partners of infected individuals will also prevent reinfection of the index case and subsequent transmission to other sexual partners. Prompt treatment of chlamydial infection...

.... blinding trachoma, pelvic inflammatory disease, ectopic pregnancy, infertility and pneumonia) could be an acceptable short-term goal. Need for a Chlamydia Vaccine Members of the major clinically relevant bacterial species of the genus Chlamydi a cause ocular, genital...

... Abstract Chlamydia trachomatis infections in pregnancy present several challenges. In addition to potentially affecting the pregnancy, the infection may also affect the developing fetus and be transmitted to the infant during parturition. C. trachomatis infection during pregnancy has been...

...) are at increased risk for STDs as a result of reported risk behaviors including sex with high-risk men. WSW should undergo routine age-based annual screening for Chlamydia trachomatis , as recommended by Centers for Disease Control and Prevention guidelines. Although incident HIV infection and a number of unsafe...

... Department of Health and Human Services, 2010. 3. Centers for Disease Control and Prevention: Chlamydia screening among sexually active young female enrollees of health plans - United States, 2000-2007. MMWR Morb Mortal Wkly Rep 2009;58:362-365. 4. Stamm WE, Jones RB, Batteiger BE: Infectious...

...References References 1. Ma B, Forney LJ, Ravel J: Vaginal Microbiome: Rethinking Health and Disease. Annu Rev Microbiol 2012;66:371-389. 2. Clarke IN: Evolution of Chlamydia trachomatis . Ann NY Acad Sci 2011;1230:E11-E18. 3. Stephens RS, Kalman S, Lammel C, Fan J, Marathe R...

...References References 1. Agrawal T, Vats V, Salhan S, Mittal A: Mucosal and peripheral immune responses to chlamydial heat shock proteins in women infected with Chlamydia trachomatis . Clin Exp Immunol 2007;148:461-468. 2. Pate MS, Hedges SR, Sibley DA, Russell MW, Hook EW 3rd, Mestecky...

... controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial. BMJ 2010;340:c1642. 3. Gottlieb SL, Berman SM, Low N: Screening and treatment to prevent sequelae in women with Chlamydia trachomatis genital infection: how...

...References References 1. Cates W Jr, Wasserheit JN: Genital chlamydial infections: epidemiology and reproductive sequelae. Am J Obstet Gynecol 1991;164:1771-1781. 2. Debattista J, Timms P, Allan J: Immunopathogenesis of Chlamydia trachomatis infections in women. Fertil Steril 2003;79...

...References References 1. Schachter J: Infection and disease epidemiology; in Stephens RS (ed): Chlamydia: Intracellular Biology, Pathogenesis, and Immunity. Washington, ASM, 1999, pp 139-169. 2. Bush RM, Everett KD: Molecular evolution of Chlamydiaceae. Int J Syst Evol Microbiol 2001;51...

... Quality 2010: HEDIS Measures of Care, Washington, NCQA, 2010, pp 43-44. 5. Gaydos CA, Ferrero DV, Papp J: Laboratory aspects of screening men for Chlamydia trachomatis in the new millennium. Sex Tansmit Dis 2008;35(suppl): S45-S50. 6. APHL/CDC Panel Summary Reports: Laboratory Diagnostic Testing...