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carcinoma

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Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 84
Published: 31 August 2020
10.1159/000457936
EISBN: 978-3-318-06670-8
... challenges. Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are types of sinonasal neuroendocrine tumor, together with olfactory neuroblastoma. They share overlapping clinical, radiological, and histopathological features, albeit with variability in behavior...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366539
EISBN: 978-3-318-02763-1
... Abstract In the realm of keratinocyte skin cancer, specific dermoscopic patterns that are associated with different stages of progression have been identified, which allows for an improved clinical diagnosis and differentiation actinic keratosis, intraepidermal carcinoma (also commonly named...
Book Chapter
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Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 84
Published: 31 August 2020
10.1159/000457932
EISBN: 978-3-318-06670-8
... Abstract Squamous cell carcinoma (SCC) is one of the most common malignant neoplasms involving the anterior skull base, resulting from local invasion from an adjacent anatomical region. The primary sites of origin are most frequently the nasal cavity and paranasal sinuses, and less often...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 84
Published: 31 August 2020
10.1159/000457939
EISBN: 978-3-318-06670-8
... Abstract Sinonasal adenoid cystic carcinoma is a rare malignancy characterized by an insidious growth pattern and a tendency for perineural spread along major and minor nerves, resulting in invasion of the skull base and intracranial extension. Therefore, many patients present with advanced...
Book
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 83
Published: 19 February 2019
10.1159/000492306
EISBN: 978-3-318-06389-9
... Abstract Pre-treatment clinical and radiological evaluations represent a key step in the proper management of hypopharyngeal carcinoma. First, office-based endoscopy allows the assessment of superficial tumor extension, signs of laryngeal infiltration, and the overall residual function...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491039
EISBN: 978-3-318-06409-4
... Abstract Parathyroid carcinoma (PC) is a rare endocrine malignancy, accounting for <1% of all cases of sporadic primary hyperparathyroidism (PHPT) and up to 15% in the hereditary hyperparathyroidism-jaw tumor syndrome. Genomic alterations identified in PC are mostly represented by CDC73...
Book Chapter
Series: Monographs in Clinical Cytology
Volume: 24
Published: 14 December 2017
10.1159/000479769
EISBN: 978-3-318-06141-3
... Invasive breast cancer is the most common carcinoma in women, accounting for 23% of all cancers worldwide [Ferlay et al., 2008]. Its incidence increases with age and varies markedly in different geographical areas due to different lifestyles and genetic factors. Australia, Europe, and North...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441879
EISBN: 978-3-318-05651-8
... Abstract We report a retrospective study of 26 patients with maxillary sinus squamous cell carcinoma who were treated at the Sapporo Medical University between January 2002 and December 2008. The 5-year local control rate was 85.7% in patients with stage T2-3 disease and 61.0% in patients...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441881
EISBN: 978-3-318-05651-8
.... In the present study, we found a high expression of JAM-A in head and neck squamous cell carcinoma (HNSCC) as well as β-catenin in immunohistochemistry. The expression of JAM-A and β-catenin was of a low level in differentiation-induced cancer pearl regions of HNSCC. Real-time PCR showed the high expression...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441884
EISBN: 978-3-318-05651-8
... are thought to have critical but contrasting roles through facilitating antitumor immunity and inducing oncogenic factors. However, the role and function of inflammasomes in oropharyngeal carcinoma remain unclear. We analyzed nine specimens of oropharyngeal squamous cell carcinoma (SCC) and determined...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 45
Published: 21 March 2016
10.1159/000442276
EISBN: 978-3-318-02738-9
... Abstract Radioactive isotopes of radioiodine are frequently used in differentiated thyroid carcinoma (DTC) both for diagnosis and therapy. Their accumulation in thyroid cancer tissue is dependent on the expression and activity of the sodium-iodide symporter (NIS). Scintigraphic imaging using...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366531
EISBN: 978-3-318-02763-1
... Abstract Ultraviolet (UV) radiation is likely to drive the initiation and progression of skin cancer from actinic keratosis to squamous cell carcinoma. Signs of photodamage occur at multiple steps. UV radiation damages many cellular constituents, including lipids, proteins and DNA, all of which...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000367959
EISBN: 978-3-318-02763-1
... early squamous cell carcinoma (SCC) in situ , although debate over their classification continues. Anti-EGFR therapies have been approved for the treatment of several malignancies and are undergoing trials for others [<citeref rid="ref1">1</citeref>], including advanced cutaneous squamous...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366532
EISBN: 978-3-318-02763-1
... Abstract Squamous skin cancer, which is commonly called squamous cell carcinoma (SCC), represents an immunological puzzle. The major skin cancers (SCC, basal cell carcinoma, Merkel cell carcinoma, and melanoma) and actinic keratosis (AK), as a potential precursor lesion of SCC, are common...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366534
EISBN: 978-3-318-02763-1
... Abstract This manuscript focuses on the use of mice to study the genetics and biology of cutaneous squamous cell carcinoma (SCC). Mice develop actinic keratosis-like lesions and SCC resembling those seen in humans. As an animal model, the mouse provides great experimental flexibility and has...