Search Results for biomarker

... Abstract Stratified medicine involves the use of biomarkers to differentiate patient populations into subsets that provide more detailed information about the specific causes of conditions, and predict how patients will respond to a given drug or combination of drugs. Biomarker-driven patient...

... Abstract The identification of peripheral biomarkers for schizophrenia is of great clinical importance, with the potential to considerably improve its diagnosis, treatment and prognosis. However, despite intense research efforts and the discovery of several potential candidates for markers...

... balance in HF may be complex and depend largely on underlying pathophysiology; however, in addition to simple fluid balance (intake minus output) measurement, newer biomarkers (i.e. B-type natriuretic peptides) and novel technology (i.e. impedance cardiography) are proving to be useful for detection...

... online to electrospray ionization time-of-flight mass spectrometry(CE-MS) was applied to human urine to identify biomarkers for clinical diagnostics. Toextract the information of the CE-MS spectra in a timely fashion, software was designed toautomatically deconvolute and normalize the spectra...

... to the biomarker data, as well as give clues to pathogenesis andperhaps therapy. In this chapter, data from the scientific literature are considered broadly,where oxidative damage to DNA has been analysed either in tissues or in extracellular matrices,such as urine, in various groups of non-malignant disease...

... diagnostic and prognostic biomarkers. However, recent discoveries of certain key genomic alterations, such as chromosome translocations, copy number alterations, and mutations, provide new insights into the molecular pathogenesis of these lesions and may help to better define them. It is also hoped...

... sensitizer or chemotherapy to reduce the radiotherapy resistance caused by hypoxia. For some patients, one of these approaches can be beneficial but for others could lead to unacceptable side effects. Therefore, it is highly desirable to make the selection upfront. The use of imageable biomarkers could...

... from intracranial stenosis degree towards intracranial atherosclerotic plaque composition and activity. Characterization of the vulnerable ICAS patient may be improved with biomarker research. The latest contributions in this field help support the hypothesis that inflammation determines the risk...

... Abstract Current biomarkers used in health care and in nutrition and health research are based on quantifying disease onset and its progress. Yet, both health care and nutrition should focus on maintaining optimal health, where the related biology is essentially differing from biomedical...

... or status of these parameters in a dynamic way, particularly via noninvasive methods, are urgently required. In this chapter, we summarize recent advances in the identification of biomarkers of liver diseases: biomarkers corresponding to inflammation, cell death, fibrosis, and the development of malignancy...

... Abstract Together with the improvement of pulmonary arterial hypertension (PAH) management arises the need for adequate surrogate markers for treatment decision and follow-up. In this setting, biomarkers play a definitive role. A number of biomarkers addressing specific features...

... matrixproteinase-2 and plasminogen activator inhibitor-1 be used as biomarkers of peritoneal membrane alterations in peritoneal dialysis patients? Perit Dial Int 2013;33:529-537. 3. Lopes Barreto D, Krediet RT: Current status and practical use of effluent biomarkers in peritoneal dialysis patients. Am J Kidney...