... Abstract This article explores the challenges and opportunities of applying Evidence-Based Medicine (EBM) to the field of gut microbiota research. EBM has revolutionized healthcare by integrating the best available evidence with clinical expertise and patient values. However, EBM has also faced...

... Abstract There has been a significant increase in the number of people shifting towards plant-based dietary patterns over the past decade due to interest in protecting the health of the planet as well as improving human health. Studies have shown that vegetarian diets are associated...

... due to the proposed humoral theory behind these disorders. Pathogenetic circulating molecules in critical illness (damage- and pathogen-associated molecular patterns) cannot be sufficiently removed by classic continuous renal replacement therapies. New sorbent-based extracorporeal therapies have...

... and female in clinical practice, both being valuable parameters of insulin resistance, hepatic steatosis and serum T [ 11 , 12 ]. The skinfold method is based on the measurement of thickness at triceps, midaxilla, supraspinale levels in men, while at levels of midaxilla, biceps, medial calf...

... Abstract Currently accepted “best practice” for managing breastfeeding effectively (WHO/UNICEF) is largely based on a historical view of how babies remove milk from the breast, which had persisted for several centuries. The collective wisdom was verified by imaging studies in the 1950s...

..., expensive outcomes). Recently conducted questionnaire surveys show that a gap exists between research findings and professional practices in relation to DCL management. It is, therefore, important to identify the barriers to the implementation of evidence-based dentistry into dental practices...

... Abstract Current cell-based immunotherapeutic strategies attempt to produce and maintain an immune response against glioma cells by artificially stimulating the immune system using passive and/or active approaches. Cellular immunotherapy is taken to mean the administration of live immune cells...

... where access to healthcare is more weak. In Burkina Faso, the approach of community-based interventions is recognized by health authorities as an indispensable way to “accelerate and promote the health consciousness of populations and strengthen community capacity to participate more in health-related...

...-based screening participants in Okinawa, Japan. Okinawa was one of the longevity areas in the world; however, the incidence and prevalence of ESRD increased. In Japan, the incidence of ESRD is 2 times higher in men compared to that in women. Such gender difference in ESRD incidence may be explained...

... crossover at the time of tumor progression. Based on 1p/19q co-deletion as an inclusion criterion, two phase III studies on anaplastic gliomas were launched some years ago, before the release of the final results of the RTOG 9402 and EORTC 26951 trials. For patients with newly diagnosed anaplastic...

... in global community-based preventive interventions. Introduction Athletes entering high-level sport competition are required to abide by the rules as set by the relevant governing bodies, which include a precise list of prohibited performance-enhancing practices and methods, commonly referred...

... for the preparation of biomaterials and the characteristic properties of polymer biocompatibility are presented. In addition, an overview is given of the recent experimental progress made in the screening of biocompatible polymers based on the biointerfacial water structure through precision polymer synthesis...

... summarizes recent progress in the efforts to induce donor-specific tolerance across the full major histocompatibility barrier by strategies based on defined populations of cells, including dendritic cells, mesenchymal stem cells, and regulatory T cells, as well as more recent studies to utilize combinatorial...

... Abstract In India, a rights-based approach has been used to address large-scale malnutrition, including both micro- and macro-level nutrition deficiencies. Stunting, which is an intergenerational chronic consequence of malnutrition, is especially widespread in India (38% among children under 5...

...% of ICH patients had hyponatremia <135 mmol/l. Hyponatremia was associated with increased early mortality [ 18 ]. It is unclear whether the correction of hyponatremia is beneficial to ICH patients, but based on the association of hyponatremia with an increased risk of brain edema, we advise paying...

..., discounting and so forth). Thus, millions of variants can be used. Value-based medicine® (VBM) cost-utility analysis standardizes these variants so that one VBM analysis is comparable to another. This system provides a highly rational methodology that allows providers and patients to quantify and compare...

... for surgery or failed surgery. Vagus nerve stimulation (VNS) might be an option for these very refractory patients. We carried out an evidence-based search to identify the best evidence presently available related to the use of VNS. We used multiple searchable databases (primary: PubMed-MEDLINE, EMBASE...

... therapy [ 1 ]. Cell sheet-based engineered tissue consisting of 2-dimensional confluent cells without any added materials has been developed.Cell sheets can be harvested from intelligent culture dishes by simply lowering the temperature, given that the temperature-responsive polymer poly( N...