Search Results for atop

... Abstract Atopic dermatitis was described in 1933 but exists since antiquity. We review descriptions of a childhood skin disease compatible with our modern diagnosis of atopic dermatitis, in ancient medicine and in nineteenth century dermatology texts. We identify Hebra's prurigo and Besnier's...

... Abstract The prevalence of atopic dermatitis (AD), the most common inflammatory skin diseasein children, has increased over the last decade. Although there is a genetic predisposition toAD, there is strong evidence suggesting a crucial role for environmental factors. The etiologyof AD...

... Abstract Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease which usuallystarts during the first years of life. In the management of AD, the correct approach requires acombination of multiple treatments to identify and eliminate trigger factors, and to improvethe alteration...

... Abstract Atopic dermatitis (synonym atopic eczema, AD) is a chronic inflammatory skin disorder essentially characterised by a red “itchy” skin rash. The condition is prevalent around the world, affecting 15-30% of children and 2-10% of adults [Odhiambo et al.: J Allergy Clin Immunol 2009;124...

... Abstract Atopic dermatitis (also termed atopic eczema and infantile eczema), a chronic, itchy,inflammatory skin disease that sets on at infancy or early childhood, is observed with increasingprevalence around the world, particularly in developed nations. Although sufficient evidencesare not yet...

... Abstract Patients with atopic dermatitis (AD) suffer from chronic inflammatory dermatitis and antihistamine-resistant itch. The management of intractable pruritus in AD is important, requiring the development of new therapeutic approaches. At present, the standard treatments for AD include...

... Abstract Approximately one-third of children with severe atopic eczema suffer from a food allergy, whereas in adult patients, food allergies are rare. In child patients, three different clinical reaction patterns can be differentiated as follows: (1) immediate-type reactions, (2) isolated late...

... Abstract In both clinical experience and molecular genetic studies, atopic diseases (asthma, rhinoconjunctivitis and eczema) have been found to be strongly genetically influenced. The epidermal protein filaggrin seems to play a crucial role and is encoded within the so-called epidermal...

...-A have been detected in skin tissue of atopic dermatitis (AD) patients and correlate with disease activity. The vascular changes in the skin of AD patients appear to be linked to the inflammatory process. Effector cells of skin inflammation (human mast cells, basophils, eosinophils, macrophages...

... and efficient host defence responses. Patients with atopic dermatitis (AD) exhibit both, impaired skin barrier function and defects in skin innate immunity. As a result, AD patients frequently develop skin infections which contribute to the pathogenesis and the course of their chronic inflammatory skin...

... Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by eczematous skin lesions, pruritus and typical histopathological features. T cells are thought to play a key role, but B cells might also participate in the pathogenesis of AD. In two investigator-initiated...

... Abstract Recent investigations have shown atopic dermatitis (AD) results from the interplay of epidermal barrier defects, immune dysfunction and environmental triggers. These discoveries teach the importance of addressing all of these factors in treating patients. The barrier issues remind us...