... Abstract Remodeling of the vascular wall plays a central role in many physiological processes,but also in the pathogenesis of cardiovascular diseases such as atherosclerosis and restenosis.Atherosclerosis represents the major cause of death and disability in adult populations ofWestern...

... Abstract Atherosclerosis is the main underlying cause of ischemic heart disease and related acute cardiovascular complications, including myocardial infarction and stroke. In view of the failure of statins to demonstrate a beneficial effect in all patients, exhaustive research efforts have...

... growth on the development of atherosclerosis and its risk factors. Historical Overview The concept that factors in early life have long-term biological effects first emerged in the 1930s. McCay [ 1 ] showed that rats whose growth was stunted by restricting their food intake had a lower incidence...