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Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363565
EISBN: 978-3-318-02602-3
... Abstract Is there an autism spectrum disorder (ASD) cognitive profile, i.e. a consistent, disorder-specific pattern of cognitive peaks and troughs found in a substantial proportion of people with ASD? Almost all research into ASD cognition is not designed to answer this question, as studies...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363561
EISBN: 978-3-318-02602-3
... Abstract It is a rule rather than an exception that mental disorders occur in complex and manifold forms, and a number of models have been proposed to explain this co-occurrence or co-‘morbidity'. Autism spectrum disorders (ASD, i.e. autistic disorder, Asperger syndrome, and pervasive...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363562
EISBN: 978-3-318-02602-3
... Abstract Individuals with autism spectrum disorders (ASD) are at an increased risk for medical comorbidities which often remain undetected and negatively impact their developmental progress. These include gastrointestinal disorders, oral health problems, sleep disorders, and epilepsy. Greater...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363613
EISBN: 978-3-318-02602-3
... Abstract As autism spectrum disorders (ASD) are pervasive developmental disorders with onset early in life, attempts have made to diagnose ASD as early as possible. The available screening instruments for young children in the second year of life (aged 12 or 18 months) do not show a clinically...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363587
EISBN: 978-3-318-02602-3
... Abstract Numerous neuroimaging studies of autism spectrum disorders (ASD) have been conducted. Although many of the results of these studies do not overlap, some evidence has accumulated in support of the existence of some atypical brain morphology and function patterns. Indeed, studies have...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363590
EISBN: 978-3-318-02602-3
... architecture of the risk for autism spectrum disorders (ASD). Indeed, from a population genetics perspective, it can be argued that an accurate synopsis of the genetic architecture of ASD is already in hand. Integrating all of the evidence, there can be no doubt that both rare and common variations play a role...
Book
Book Cover Image
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/isbn.978-3-318-02602-3
EISBN: 978-3-318-02602-3
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363593
EISBN: 978-3-318-02602-3
... Abstract Major advances in neuroscience have highlighted previously elusive molecular pathways for autistic spectrum disorders (ASD) which are essential to the identification of molecular targets for drug discovery. The evidence of the heritability of ASD is now well established, and the last...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363614
EISBN: 978-3-318-02602-3
..., such as restricted and repetitive behaviors, aggression, irritability, and attention deficit/hyperactivity disorder (ADHD)-like symptoms, presented by children and adolescents with autism spectrum disorders (ASD) cause important alterations in social and communicational functions and interfere with the outcomes...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363611
EISBN: 978-3-318-02602-3
... Abstract Multiple observations indicate that environmental and epigenetic factors play an important role in the emergence of autism spectrum disorders (ASD). Growing ASD incidence rates, the incomplete penetrance of many rare variants linked to autism, and increased exposure to environmental...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363586
EISBN: 978-3-318-02602-3
...-reports of sensory atypicalities abound in the literature. Similarly, early clinical accounts of autism and autism spectrum disorders (ASD) [ 2 ] invariably contained a reference to inappropriate, usually increased, responses to sensory stimulation along with heightened apprehension in reaction...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
10.1159/000363585
EISBN: 978-3-318-02602-3
... Abstract Autism spectrum disorder (ASD) includes a family of neurodevelopmental disorders with very early onset that affect many aspects of behavior and cognition. In particular, it refers to a set of deficiencies concerning three major domains: social functioning, communication...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 32
Published: 28 May 2021
10.1159/000510419
EISBN: 978-3-318-06856-6
... are implicated in several disease states, including anxiety, depression, autism spectrum disorder (ASD), Alzheimer’s disease (AD), Parkinson’s disease (PD), obesity, and diabetes. Therefore, therapeutic targeting of the gut microbiota has the potential to be useful in the treatment of both stress-related...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 28
Published: 25 March 2010
10.1159/000307088
EISBN: 978-3-8055-9405-9
... that familiarity with yawning adults may be relevant to the differences between these two studies. In addition to the investigation of typical development, other scientists, including our group, have investigated the development of contagious yawning in children with autism spectrum disorders (ASD), who show...
Book Chapter
Series: Monographs in Human Genetics
Volume: 18
Published: 15 February 2010
10.1159/000287603
EISBN: 978-3-8055-9281-9
...-forming sequence, has been identified in several patients. Owing to its emerging role in neuropsychiatric disorders and the overlap of phenotypes between autism and 22q13.3 deletion syndrome, SHANK3 became eligible for mutation screening in patients with autistic spectrum disorders (ASD) and several...
Book Chapter
Series: Key Issues in Mental Health
Volume: 180
Published: 11 February 2015
EISBN: 978-3-318-02602-3
...: stability and change in clinical diagnosis and symptom presentation. J Child Psychol Psychiatry 2013;54:582-590. 24. Chawarska K, Klin A, Paul R, Macari S, Volkmar F: A prospective study of toddlers with ASD: short-term diagnostic and cognitive outcomes. J Child Psychol Psychiatry 2009;50:1235-1245...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
10.1159/000461732
EISBN: 978-3-318-06031-7
... of mood and affect [ 2 ], autism spectrum disorders (ASD) [ 2 ], Parkinson disease (PD) [ 3 ], and chronic pain [ 4 ]. Despite the remarkable support for such associations based on behavioral studies in mouse models of these disorders, there is limited information regarding the translational relevance...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 02 June 2015
10.1159/000375215
EISBN: 978-3-318-03004-4
... to have CHD [ 4 ]. Overall, the estimated heritability for CHD is 35 as compared to 85 for schizophrenia [ 5 ]. Risk differs by lesion, and some lesions like atrial septal defect (ASD), ventricular septal defect (VSD), tetralogy of Fallot, and hypoplastic left-heart syndrome (HLHS) have a 3% recurrence...
Book Chapter
Series: Monographs in Human Genetics
Volume: 17
Published: 02 October 2008
10.1159/000164847
EISBN: 978-3-8055-8654-2
... defects. Nevertheless, the spectrum of cardiac malformations has been progressively widened, including also atrioventricular canal defect (AVCD), mitral valve anomalies (MVA), atrial septal defect (ASD), aortic coarctation (AC), and other defects. The anatomic pattern of CHDs in NS and related disorders...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 02 June 2015
10.1159/000375201
EISBN: 978-3-318-03004-4
... ], created an atrial septal defect (ASD) to mix oxygenated and unoxygenated blood in infants with complete transposition of the great arteries. This palliated these neonates and was often a preliminary step to subsequent operations. A second operation developed by Russell Brock (1903-1980) [ 24...