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Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
10.1159/000431201
EISBN: 978-3-318-05565-8
... for the treatment of ocular inflammatory diseases. Anti-tumor necrosis factor agents, particularly infliximab and adalimumab, are well studied. We will review these, as well as newer options in the development of more targeted therapy, including anti-interleukins, anti-cell surface molecule biologics and interferon...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 34
Published: 09 July 2015
10.1159/000381597
EISBN: 978-3-318-05474-3
... Abstract The introduction of anti-TNF monoclonal antibodies to the therapeutic arsenal has represented a major advance in the management of Crohn's disease (CD). Anti-TNF agents are able to induce and maintain remission of the disease over time. These treatments also have the ability to close...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 34
Published: 09 July 2015
10.1159/000381601
EISBN: 978-3-318-05474-3
... Abstract Recently, the efficacy of anti-TNF agents in refractory UC patients has been reported. Promising results of large scale clinical trials encourage us. while we also have unsolved issues in daily practice such as how to evaluate mucosal healing, long-term prognosis of patients treated...
Book Chapter
Series: Contributions to Nephrology
Volume: 183
Published: 16 May 2014
10.1159/000360051
EISBN: 978-3-318-02651-1
..., and co-localization of NEP, IgG and C5b-9 within the subepithelial immune deposits, established that the disease was caused by anti-NEP antibodies [ 4 , 11 ]. NEP is not only an antigen but also an enzyme involved in the degradation of biologically active peptides such as enkephalin (for this reason...
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... Abstract sThe clinical value of an enzyme-linked immunosorbent assay (EIA) for the detection of anti-HBc IgM was evaluated by testing serum samples from the following groups of patients: 35 cases with acute viral hepatitis B (AVHB), 27 cases with hepatitis B (HB), 19 cases with chronic...
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