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Book Cover Image
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/isbn.978-3-8055-9596-4
EISBN: 978-3-8055-9596-4
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317139
EISBN: 978-3-8055-9596-4
... Abstract The first International Symposium on Animal Genomics for Animal Health (AGAH) provided an excellent venue for scientists working in the field of genomics to interact with animal health experts. This paper provides an introduction to genome-enabled tools and highlights some...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317192
EISBN: 978-3-8055-9596-4
... Abstract The first International Symposium on Animal Genomics for Animal Health, held at the World Organisation for Animal Health (OIE) Headquarter, 23-25 October, 2007, Paris, France, assembled more than 250 participants representing research organizations from 26countries. The symposium...
Book
Book Chapter
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 60
Published: 19 January 1988
10.1159/isbn.978-3-318-03324-3
EISBN: 978-3-318-03324-3
Book Chapter
Series: Monographs in Oral Science
Volume: 30
Published: 08 March 2022
10.1159/000520767
EISBN: 978-3-318-06913-6
... Abstract Research in animal models, particularly rodents, has been used as a tool for gaining insight into the genetics contribution to dental caries. This chapter dissects some of these data, particularly the early studies motivated by observations in humans, complementing them with more...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444971
EISBN: 978-3-318-05867-3
... of our knowledge of allotransplantation is derived from sacrificing laboratory animals. Rodents are preferred for their availability, low cost, and size. VCA study design is a complex science based on generations of experience with solid and composite tissue transplantation in human and animal subjects...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438877
EISBN: 978-3-318-02789-1
... and their key upstream afferents, Kiss1 neurons, to influence the timing of puberty. Special emphasis will be given to summarize information emerging from relevant preclinical (mostly rodent) animal models, and how this information might be relevant in terms of translational medicine, as it may help...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 30
Published: 28 September 2015
10.1159/000435929
EISBN: 978-3-318-05574-0
... Abstract Animal models of chronic pain have provided valuable information on the mechanisms of initiation and maintenance of the disease. Much of the research effort has targeted sensory abnormalities like hyperalgesia and allodynia. However, in the past 15 years a significant number...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 41
Published: 22 July 2015
10.1159/000381131
EISBN: 978-3-318-05457-6
... Abstract Animal models have contributed greatly to our understanding of the biology of aging and have been used to test new potential interventions to enhance survival. However, whether these interventions can modify frailty in animals is not yet clear, in part because until recently, frailty...
Book Chapter
Series: Developments in Biologicals
Volume: 135
Published: 18 April 2013
10.1159/000265588
EISBN: 978-3-318-02366-4
... Abstract The development of countermeasures to support an effective response to Transboundary Animal Diseases (TAD) poses a challenge on a global scale and necessitates the coordinated involvement of scientists from government, industry and academia, as well as regulatory entities...
Book Chapter
Series: Developments in Biologicals
Volume: 135
Published: 18 April 2013
10.1159/000171016
EISBN: 978-3-318-02366-4
... Abstract The United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS) Veterinary Services (VS) is charged with monitoring, controlling, and responding to select reportable diseases and all foreign animal diseases. Emergency Management and Diagnostics (EM...
Book Chapter
Series: Developments in Biologicals
Volume: 135
Published: 18 April 2013
10.1159/000190049
EISBN: 978-3-318-02366-4
... of the Ebola species has been found in Philippine pigs raising concerns regarding animal health and food safety. Diagnostics have so far focused on human application, but enhanced pig surveillance and diagnostics, particularly in Asia, for Ebola virus infections seem to be needed to establish reasonable...
Book
Book Cover Image
Series: Developments in Biologicals
Volume: 135
Published: 18 April 2013
10.1159/isbn.978-3-318-02366-4
EISBN: 978-3-318-02366-4
Book Chapter
Series: Biovalley Monographs
Volume: 3
Published: 28 August 2012
10.1159/000339188
EISBN: 978-3-8055-9066-2
... embryogenesis, organogenesis, after birth and in the adult, as well as in tissue repair and homeostasis. Manipulating their expression in several species has generated valuable animal models to dissect their precise function. This overview will concentrate on the role of TGF-β isoforms TGF-β1, TGF-β2 and TGF-β3...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 30
Published: 22 June 2012
10.1159/000338466
EISBN: 978-3-318-02184-4
... the severity of NSAID-induced antral ulcers in refed rats, notably converting nonhemorrhagic to hemorrhagic lesions [ 10 ]. More recently, we also found using a rat model that gastric lesions induced by acidified ASA were markedly aggravated by pretreatment of the animals with clopidogrel [ 11 , 12...
Book Chapter
Series: Frontiers of Oral Biology
Volume: 15
Published: 02 November 2011
10.1159/000329675
EISBN: 978-3-8055-9834-7
... Abstract Animal models have distinct advantages because they can mimic cellular complexities that occur in humans in vivo and are often more accurate than in vitro studies that take place on plastic surfaces with limited numbers of cell types present. Furthermore, cause and effect relationships...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 68
Published: 06 October 2011
10.1159/000325645
EISBN: 978-3-8055-9746-3
... Abstract Small size at birth is associated with increased risk of a variety of common chronic diseases in adulthood. Numerous experimental studies in animals have supported the observations in humans, demonstrating that changes in nutrition in early life can lead to altered long-term health...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 72
Published: 10 August 2011
10.1159/000324608
EISBN: 978-3-8055-9723-4
... Abstract Impaired immune regulation along the ‘mucosa-bone marrow axis’ has been postulated to play an important role in the pathogenesis of IgA nephropathy (IgAN). Animal models have allowed us to study such changes in detail. Recently, we established several useful animal models, including...