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allograft

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Book Chapter
Series: Contributions to Nephrology
Volume: 190
Published: 29 May 2017
10.1159/000468963
EISBN: 978-3-318-06061-4
... Abstract Chronic allograft injury (CAI) remains one of the biggest challenges in transplantation as it directly affects the long-term allograft survival, an area in which the scientific and transplantation communities have struggled to improve outcomes. Therefore, understanding the mechanisms...
Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
10.1159/000329395
EISBN: 978-3-8055-9811-8
... Abstract Ischemia-reperfusion (IR) injury plays a significant role in the pathogenesis of both delayed graft function (DGF) in allografts and hemodynamic mediated acute kidney injury (AKI) of native kidneys. IR injury involves the interplay of several factors, including both the innate...
Book Chapter
Series: Contributions to Nephrology
Volume: 162
Published: 28 October 2008
10.1159/000170811
EISBN: 978-3-8055-8959-8
... Abstract Background: Successful ABO-incompatible (ABOi) kidney transplantation of non-A2 renal allografts requires preconditioning to reduce anti-blood group antibody to safe lev-els in order to avoid hyperacute rejection. Unfortunately, early post-transplant acute antibody-mediated rejection...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 148
Published: 16 June 2005
10.1159/000086057
EISBN: 978-3-318-01170-8
... by ischemia-reperfusion injury and is elevated in transplantedorgans, and that rejecting allografts are infiltrated by Hsp-specific lymphocyte populationshave prompted the suggestions that Hsps and the development of anti-Hsp immune reactivitydrive transplant rejection responses. However, although...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 146
Published: 28 October 2004
10.1159/000082071
EISBN: 978-3-318-01168-5
... Abstract Donor dendritic cells (DCs) and those of host origin play key roles in the instigation andmaintenance of immune responses to organ allografts. In the normal steady state, however,DCs are important for the maintenance of central and peripheral tolerance. Moreover, thepresence of those...
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Series: Contributions to Nephrology
Volume: 120
Published: 26 June 1997
10.1159/000059824
EISBN: 978-3-318-00223-2
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