... conditions, of the adsorptive HD membrane for elderly HD patients. We have also reported that the use of β2MG adsorption columns improved the symptoms of dialysis-related amyloidosis and the number of bone cysts, which could not be improved by the high-flux hemodialyzer. Both the adsorptive HD membrane...

... Abstract Background: Idiopathic acute-on-chronic inflammation in the gastrointestinal tract is an etiology of inflammatory bowel disease (IBD). Granulocyte and monocyte adsorptive apheresis (GMA) is a nonpharmacological treatment tool for patients with IBD. Here, we present a review...

... is insufficient due to their adsorptive properties. Summary: Coagulation during hemodialysis occurs because proteins that are adsorbed to the PMMA membrane undergo structural changes and are recognized by platelets, which are then activated by adhesion to the membrane surface. In developing a new PMMA...

... Abstract The mechanism of adsorption is regulated by various factors including the nature of the sorbent and the molecules involved in the adsorption process. The design of a device for adsorption therapies must fulfil specific requirements. The device should allow the use of the minimum amount...

... describe targeted patient selection using the endotoxin activity assay and clinical phenotyping followed by adsorption of endotoxin using the PMX-HP for endotoxemic sepsis. Abstract In the fields of sepsis and systemic inflammation, endotoxin might be the most studied molecule since the term...

... therapies, nonbiological extracorporeal liver support devices are the most widely used, mainly based on detoxification by eliminating accumulated toxins notably by adsorption on specific membranes and/or with plasmapheresis. One of the most recent techniques is the double plasma molecular adsorption system...

... use of extracorporeal blood purification techniques has increased. One of the emergingtreatments in patients with severe sepsis and septic shock is coupled plasma filtration adsorption(CPFA), a novel extracorporeal blood purification therapy aimed at a nonselective reductionof the circulating levels...

... Abstract In this chapter, anticoagulation treatments for adsorption techniques in continuous renal replacement therapy (CKRT) will be reviewed. Anticoagulation used with adsorption techniques is quite different than anticoagulation in classical CKRT with nonadsorptive therapies. Regional...

... Abstract A strong rationale supports the development of adsorption-based extracorporeal blood purification in conditions such as sepsis, acute kidney disease, uremia, and acute liver failure. The retention of compounds as a consequence of acute or chronic organ dysfunction might have...

... of the Hemopurifier in patient treatment. GARNET® The GARNET® (BOA Biomedical, Cambridge, MA) therapeutic filter is another broad-spectrum, pathogen-agnostic, adsorption device that specifically targets and removes pathogens and pathogen fragments. GARNET® utilizes a proprietary bioengineered protein, Fc...

... technique. This introductive chapter aims at briefly presenting the phenomenology of the adsorption process, also providing some basic elements related to how to use equilibrium load data to define an adsorption isotherm, which can be used to size a hemoperfusion cartridge. Abstract The removal...

... and the volume of the cartridge vary according to the type of cartridge ranging between 50 Da and 60 kDa. The sorbents, the size of the cartridge, the volume of sorbent, and the pore size (which reaches 60 kDa with the HA330 cartridge) aim to take advantage of the principles of molecular adsorption in a variety...

... Abstract Due to its influence on both the filtration process and blood compatibility, protein adsorption is a fundamental aspect of plasma separation through membranes. In the filtration of solutions containing proteins, particularly blood, the transmembrane flow decreases as filtration time...

... plasma from blood and then applying adsorption to plasma or of combining HA with other extracorporeal therapies. Here, we describe a complete appraisal of current available techniques utilizing adsorption. Abstract Sorbents have been utilized in the past for intoxication and poisoning...

... adsorbent recirculating system and the Prometheus systems. Plasmafiltration adsorption dialysis is the latest technology that can combine the best processes ofblood/plasma purification in order to determine a selective and effective purification ofmolecules implicated in liver failure. ...