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adipose

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Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494901
EISBN: 978-3-318-06471-1
... Abstract Adipose tissue is an important target of androgen action in humans. Androgens exert important effects on adipose tissue biology, including fat mass expansion and distribution, insulin signalling and lipid metabolism. In conditions of female androgen excess such as polycystic ovary...
Book Chapter
Series: Frontiers in Diabetes
Volume: 23
Published: 15 September 2014
10.1159/000362472
EISBN: 978-3-318-02700-6
..., adipose tissue commonly develops dysfunctional features including an impaired capacity to sequester lipids, chronic inflammation and dysregulated adipokine secretion. This deviation from normal function is considered an important component in the aetiology of insulin resistance and T2D. However, not all...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 43
Published: 12 June 2014
10.1159/000360560
EISBN: 978-3-318-02674-0
... Abstract Adipose tissue (AT) was long perceived as a passive lipid storage depot but it is now considered as an endocrine organ that produces a large number of mediators that affect metabolism, inflammation and coagulation. In obesity, the increased size of adipocytes and chronic low-grade...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 42
Published: 10 April 2014
10.1159/000358320
EISBN: 978-3-318-02639-9
... Abstract Brown adipose tissue (BAT) has the unique ability to oxidize fatty acids to generate heat, a process termed thermogenesis. The mitochondrial uncoupling protein 1 is predominantly expressed in BAT and controls the thermogenetic properties of this tissue. Since activated BAT dissipates...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 73
Published: 26 October 2012
10.1159/000341287
EISBN: 978-3-318-02116-5
... fat and fat distribution, significant differences can exist in metabolic outcomes, and the phenomenon of metabolically healthy obese has been well described [4]. More recent data suggest the alternative hypothesis relating excess adipose tissue to disease risk based on the metabolic function...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 68
Published: 06 October 2011
10.1159/000325884
EISBN: 978-3-8055-9746-3
... Abstract The main aspects of infant feeding that have been studied in humans in association with the subsequent development of adipose tissue include breastfeeding, rapid infancy weight gain, and weaning practices. While observational studies have consistently shown a protective effect...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 37
Published: 12 August 2010
10.1159/000319991
EISBN: 978-3-8055-9522-3
... Abstract Adipose tissue accounts for approximately 20% (lean) to >50% (in extreme obesity) of body mass and is biologically active through its secretion of numerous peptides and release and storage of nutrients such as free fatty acids. Studies in rodents and humans have revealed that body...
Book Chapter
Series: Endocrine Development
Volume: 19
Published: 17 June 2010
10.1159/000316893
EISBN: 978-3-8055-9451-6
... or the adipose transcription factor PPARΓ. Importantly, lamin A/Cmutations are also responsible for metabolic laminopathies, resembling the metabolic syndrome and progeria, a syndrome of premature aging. A number of lipodystrophic patients remain undiagnosed at the genetic level. Acquired lipodystrophy can...
Book Chapter
Series: Endocrine Development
Volume: 19
Published: 17 June 2010
10.1159/000316895
EISBN: 978-3-8055-9451-6
... Abstract The discovery of leptin has clearly demonstrated a relationship between body fat and the neuroendocrine axis since leptin influences appetite and the reproductive axis. Since adipose tissue is a primary source of leptin, adipose tissue is no longer considered as simply a depot to store...
Book Chapter
Series: Endocrine Development
Volume: 19
Published: 17 June 2010
10.1159/000316899
EISBN: 978-3-8055-9451-6
... a detrimental fetal environment or a genetic susceptibility or an interaction between the two and of the particular dynamic changes in adiposity that occur during catch-up growth. The relative impact of early postnatal events in relation to fetal growth has to be considered for designing health policy...
Book Chapter
Series: Endocrine Development
Volume: 19
Published: 17 June 2010
10.1159/000316900
EISBN: 978-3-8055-9451-6
... Abstract There are more and more data supporting the importance of nervous regulation of both white and brown adipose tissue mass. This short paper will review the different physiological parameters which are regulated such as metabolism (lipolysis and thermogeneis), secretory activity (leptin...
Book
Book Cover Image
Series: Endocrine Development
Volume: 19
Published: 17 June 2010
10.1159/isbn.978-3-8055-9451-6
EISBN: 978-3-8055-9451-6
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 101
Published: 03 May 2010
10.1159/000314515
EISBN: 978-3-8055-9428-8
...Obesity Obesity can be described as the accumulation of adipose tissue to the extent that health may be impaired. An excess of body fat, and in particular of abdominal fat, is associated with multiple complications, leading to poor health. With increasing degrees of obesity...
Book Chapter
Book Chapter
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 65
Published: 22 January 2007
10.1159/000098809
EISBN: 978-3-318-01343-6
... Abstract An overview of various proposed sealing procedures of the oval window proposed forstapedectomy or stapedotomy are presented. These include vein graft, adipose tissue andsubstances like Gelfoam or Merogel. The advantages and pitfalls with these materials arediscussed. ...
Book Chapter
Series: Contributions to Nephrology
Volume: 151
Published: 17 August 2006
10.1159/000095320
EISBN: 978-3-318-01384-9
... Abstract During the last decade white adipose tissue was recognized as an active endocrineorgan and a source of many proinflammatory cytokines, chemokines, growth factors andcomplement proteins called ‘adipokines’ or ‘adipocytokines’. The contribution of differentcell types which compose...
Book Chapter
Series: Contributions to Nephrology
Volume: 151
Published: 17 August 2006
10.1159/000095327
EISBN: 978-3-318-01384-9
... of adipokines including leptin, adiponectin andvisfatin, as well as a cytokines (here defined as signaling proteins mainly secreted by othercells present in adipose tissue, but sometimes also to a lesser degree by adipocytes per se),such as resistin, tumor-necrosis factor-α and interleukin-6. Adipokine serum...
Book Chapter
Book Chapter