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acetylation

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Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441867
EISBN: 978-3-318-05651-8
... to investigate the behavior of primary cilia and tricellular tight junction proteins during the differentiation of sensory hair cells. In undifferentiated cells (incubated at 33°C), many acetylated tubulin-positive primary cilia were observed, and each was accompanied with an γ-tubulin-positive basal body...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 101
Published: 03 May 2010
10.1159/000314514
EISBN: 978-3-8055-9428-8
... epigenetic events such as DNA hypermethylation and altered histone acetylation have been observed in cancer. To control histone acetylation, a balance exists in normal cells between histone acetyltransferase and histone deacetylase (HDAC) activities, and when this balance is disrupted, cancer development can...
Book
Book Cover Image
Series: Antibiotics and Chemotherapy
Volume: 37
Published: 11 June 1987
10.1159/isbn.978-3-318-03212-3
EISBN: 978-3-318-03212-3
Book
Book Cover Image
Series: Antibiotics and Chemotherapy
Volume: 34
Published: 15 April 1985
10.1159/isbn.978-3-318-03209-3
EISBN: 978-3-318-03209-3
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 27
Published: 17 November 2010
10.1159/000319526
EISBN: 978-3-8055-9606-0
... category of proteins harboring domains that are able to bind specifically to certain classes of epigenetic marks on histones or DNA. These classes of proteins include bromo-, chromo- or CXXC domains, which interact selectively with acetylated lysines, methylated lysines and methylated DNA, respectively...
Book Chapter
Series: Endocrine Development
Volume: 20
Published: 17 December 2010
10.1159/000321232
EISBN: 978-3-8055-9644-2
... and a central component of the self-oscillating transcription factor loop that generates circadian rhythms, represses GR transcriptional activity by acetylating lysine residues within the ‘lysine cluster’ located in the hinge region of the receptor. This Clock-mediated repression of GR transcriptional activity...
Book
Book Cover Image
Series: Antibiotics and Chemotherapy
Volume: 31
Published online: 01 January 2015
Published in print: 17 December 1981
10.1159/isbn.978-3-318-03206-2
EISBN: 978-3-318-03206-2
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 101
Published: 03 May 2010
10.1159/000314513
EISBN: 978-3-8055-9428-8
... acetyltransferase (HAT) activity and activating histone deacetylases (HDACs)/sirtuins. It has been reported that in severe asthma and in chronic obstructive pulmonary disease (COPD) patients, oxidative stress not only activates the NF- κ B pathway but also alters the histone acetylation and deacetylation balance...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 76
Published: 05 August 2013
10.1159/000350224
EISBN: 978-3-318-02409-8
... free carnitine pool is delivered to the catalytic site of CPT1 in a 1:1 exchange with acylcarnitine produced from the CPT1 reaction, and is hypothetically limiting to CPT1. Excess acetyl-CoA from the PDC reaction is buffered by the large extramitochondrial free carnitine pool via the CAT reaction...
Book Chapter
Series: Key Issues in Mental Health
Volume: 181
Published: 15 January 2016
10.1159/000440922
EISBN: 978-3-318-05621-1
... identified as a potential mechanism in the development of psychosis. N-acetyl-cysteine, a precursor of GSH, has been trialed in chronic schizophrenia and has shown a beneficial impact on negative symptoms and extrapyramidal side effects; trials are currently underway in first-episode psychosis and UHR...
Book Chapter
Series: Monographs in Oral Science
Volume: 25
Published: 24 June 2014
10.1159/000359942
EISBN: 978-3-318-02553-8
... as a consequence of medication such as tranquilizers, antihistamines, antiemetics and antiparkinsonian medicaments or of salivary gland dysfunction. Above all, patients should be aware of the potential demineralization effects of oral hygiene products with low pH. Acetyl salicylic acid taken regularly in the form...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 100
Published: 27 May 2014
10.1159/000358622
EISBN: 978-3-318-02195-0
... deviation and immune regulation evoked by the maternal and newborn microbial environment probably operate in preventing allergen-specific Th2 responses. However, microbe-related protection from allergy seems to mainly depend on epigenetically controlled acetylation of the IFNG promoter of CD4+ T cells. Even...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 72
Published: 10 August 2011
10.1159/000324610
EISBN: 978-3-8055-9723-4
..., UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyl-transferase 2, were significantly down regulated in tonsillar CD19-positive B lymphocytes from IgAN patients compared to control as determined by real-time RT-PCR. In contrast, the level of sialyltransferase was not significantly...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 101
Published: 03 May 2010
EISBN: 978-3-8055-9428-8
...:673-682 17. Choi KC, Jung MG, Lee YH, et al: Epigallocatechin-3-gallate a histone acetyltransferase inhibitor inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation. Cancer Res 2009;69:583-592 18. Dong Z, Ma W, Huang C, Yang CS: Inhibition of tumor promoter...