New high-precision technologies for the planning and delivery of radiotherapy are major advances in cancer treatment. This volume is a comprehensive guidebook to these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity modulated radiation therapy (IMRT), 4D and adaptive treatment planning are clearly explained, and the new target localization and image-guided radiotherapy (IGRT) systems are comprehensively reviewed. Clinical tutorials fully illustrate the target definitions for the major cancer sites, and techniques for organ motion management are shown. In addition, chapters explore the technical basis for stereotactic body radiotherapy (SBRT) and the latest clinical experience with it for most organ sites. In this volume, foremost authorities explain the important new techniques and technologies of radiation oncology, and give essential treatment guidelines for its clinical and technical practitioners. (A Karger "Publishing Highlights 1890–2015" title)
II. IMRT / IGRT Clinical Treatment Programs: Partial Breast Irradiation: Patient Selection, Guidelines for Treatment, and Current Results Free
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Published:2007
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Book Series: Frontiers of Radiation Therapy and Oncology
Peter Y. Chen, Frank A. Vicini, 2007. "Partial Breast Irradiation: Patient Selection, Guidelines for Treatment, and Current Results", IMRT, IGRT, SBRT - Advances in the Treatment Planning and Delivery of Radiotherapy, J.L. Meyer, B.D. Kavanagh, J.A. Purdy, R. Timmerman
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Abstract
Studies evaluating selected patients treated with partial breast irradiation (PBI) in accelerated fractionation schemes have demonstrated the equivalence of PBI with traditional whole-breast irradiation. The major advantage of PBI is the time compression of treatment down to less than 1 week compared with 6.5 weeks for whole-breast external beam treatments. Four techniques are available to deliver PBI. These include interstitial brachytherapy multicatheter systems, the Mammosite Radiation Therapy System applicator, external beam three-dimensional conformal radiation therapy and intraoperative radiation therapy. For the two brachytherapy techniques of multicatheter implantation and the Mammosite, accurate placement is achieved with image guidance via intraoperative ultrasonography, mammography, and/or CT scanning. Technologies such as image-guided cone beam CT assure accurate delivery of PBI with external beam three-dimensional conformal radiation therapy. Results of PBI show excellent control rates with mild toxicities; cosmetic outcomes are good to excellent in the vast majority of patients.