657a - 657a: Clinical and Laboratory Studies on Six Cases of American Trypanozomiasis (Chagas Disease) Transmitted by Blood Transfusion Free
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Published:1959
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Discontinued Book Series: Current Studies in Hematology and Blood TransfusionSubject Area: Hematology
V. Amato. Neto, A. Biancalana, O. Mellone, 1959. "Clinical and Laboratory Studies on Six Cases of American Trypanozomiasis (Chagas Disease) Transmitted by Blood Transfusion", International Society of Blood Transfusion: 7th Congress, Rome, September 1958: Proceedings, L.P. Holländer
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Abstract
Six cases of American Trypanozomiasis transmitted by blood transfusion are studied. In two of them the disease was manifested as an acute infection similar to those acquired by natural way with the exception of incubation time which was 30 and 37 days instead of 4 to 10 in the natural infection. Another patient showed cardiac manifestations two months after the blood transfusion. Three other recep¬tors infected through blood transfusion did not show any symptoms which might be attributed to the acute stage of Chagas disease. The transfusional transmission of the diseases was proved by direct finding of the trypanozomes in blood smears in three cases and through xenodiagnosis in five cases. The complement-fixation test (Machado-Guerreiro reaction) was positive in all cases but one where the test remained negative during six years in spite of the presence of parasites in the circulating blood.