Periodontal Disease
Our understanding of the etiopathology of periodontal disease has changed greatly over the last decade. The huge diversity of species within the microbial biofilm and the enormous multi-layered complexity of the innate, inflammatory and adaptive immune responses generated in response to it warrant study and discussion. Comprising reviews from renowned experts in the field, this book presents a comprehensible overview of this exciting and pertinent subject matter. It provides new insights into the structure and composition of subgingival biofilms and the nature of the extracellular matrix. Further, a summary of current understanding of subgingival microbial diversity and an overview of experimental models used to dissect the functional characteristics of subgingival communities are presented. Other articles discuss the innate cellular and neutrophil responses to the periodontal biofilm. The role of antimicrobial peptides in the host response to biofilm bacteria and modern approaches to nonsurgical biofilm management are also discussed. Finally, this volume addresses advances in antibiotic use and proposes a paradigm shift in the pharmacological approach to periodontal disease management.
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Table of Contents
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1 - 16: Subgingival Biofilm StructureByVincent Zijnge;Vincent ZijngeaDepartment of Oral Microbiology, University of Umeå, Umeå, Sweden;Search for other works by this author on:Thomas Ammann;Thomas AmmannbInstitute of Oral Biology, Section of Oral Microbiology and Immunology, University of Zürich, Zürich, SwitzerlandSearch for other works by this author on:Thomas Thurnheer;Thomas ThurnheerbInstitute of Oral Biology, Section of Oral Microbiology and Immunology, University of Zürich, Zürich, SwitzerlandSearch for other works by this author on:Rudolf GmürRudolf GmürbInstitute of Oral Biology, Section of Oral Microbiology and Immunology, University of Zürich, Zürich, SwitzerlandSearch for other works by this author on:
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17 - 40: Microbial Diversity and Interactions in Subgingival Biofilm CommunitiesByPatricia I. DiazPatricia I. DiazDivision of Periodontology, Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, The University of Connecticut Health Center, Farmington, Conn., USASearch for other works by this author on:
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41 - 55: Innate Cellular Responses to the Periodontal BiofilmByManju Benakanakere;Manju BenakanakereDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USASearch for other works by this author on:Denis F. KinaneDenis F. KinaneDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USASearch for other works by this author on:
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56 - 83: Neutrophils in Periodontal InflammationByDavid A. Scott;David A. ScottaCenter for Oral Health and Systemic Disease andbDepartment of Microbiology and Immunology, University of Louisville, Louisville, Ky., USASearch for other works by this author on:Jennifer KraussJennifer KraussaCenter for Oral Health and Systemic Disease andSearch for other works by this author on:
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84 - 98: Antimicrobial Peptides in Periodontal Innate DefenseBySven-Ulrik GorrSven-Ulrik GorrDepartment of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, Minn., USASearch for other works by this author on:
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99 - 116: Modern Approaches to Non-Surgical Biofilm ManagementByDanae Anastasia ApatzidouDanae Anastasia ApatzidouDepartment of Preventive Dentistry, Periodontology and Biology of Implants, Dental School, Aristotle University of Thessaloniki, Thessaloniki, GreeceSearch for other works by this author on:
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117 - 132: Animal Models to Study Host-Bacteria Interactions Involved in PeriodontitisByDana T. Graves;Dana T. GravesaDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USA;Search for other works by this author on:Jun Kang;Jun KangaDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USA;bDepartment of Periodontology, Hospital and School of Stomatology, Peking University, Beijing, PR China;Search for other works by this author on:Oelisoa Andriankaja;Oelisoa AndriankajaaDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USA;Search for other works by this author on:Keisuke Wada;Keisuke WadaaDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USA;Search for other works by this author on:Carlos Rossa, Jr.Carlos Rossa, Jr.cDepartment of Diagnosis and Surgery, School of Dentistry at Araraquara, Universidade Estadual Pauliusta, Araraquara, BrazilSearch for other works by this author on:
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133 - 148: Antimicrobial Advances in Treating Periodontal DiseasesByAndrea MombelliAndrea MombelliDepartment of Periodontology and Oral Pathophysiology, School of Dental Medicine, University of Geneva, Geneva, SwitzerlandSearch for other works by this author on:
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149 - 159: Regenerative Periodontal TherapyByDaniel W.K. Kao;Daniel W.K. KaoDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USASearch for other works by this author on:Joseph P. FiorelliniJoseph P. FiorelliniDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa., USASearch for other works by this author on:
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160 - 176: Paradigm Shift in the Pharmacological Management of Periodontal DiseasesByHatice Hasturk;Hatice HasturkDepartment of Periodontology, The Forsyth Institute, Cambridge, Mass., USASearch for other works by this author on:Alpdogan Kantarci;Alpdogan KantarciDepartment of Periodontology, The Forsyth Institute, Cambridge, Mass., USASearch for other works by this author on:Thomas E. Van DykeThomas E. Van DykeDepartment of Periodontology, The Forsyth Institute, Cambridge, Mass., USASearch for other works by this author on: