Pulmonary Vascular Disorders
The pulmonary circulation is by nature difficult to evaluate for the clinician and a challenge to investigate by radiographic and hemodynamic methods. In recent years, the field has been revolutionized by major improvements in diagnostic approaches and therapies. Tools for the classification, diagnosis, and management of pulmonary embolism and pulmonary hypertension have been developed and optimized, providing clinicians with detailed and updated guidelines. This volume provides the latest information on the fast-growing and challenging field of acute and chronic pulmonary vascular disorders from some of the field’s major leaders in research, education, and care. The topics discussed are relevant to chest physicians, thoracic surgeons, nurses, students, and teachers, and a well-balanced mix of contributions ensures that doctors, clinicians, and institutions from all around the world will find the information presented to be both informative and useful to their situations.
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1 - 13: Updated Clinical Classification of Pulmonary HypertensionByDavid Montani;David MontaniaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre;bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart;cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical, Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:Gérald SimonneauGérald SimonneauaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre;bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart;cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical, Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:
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14 - 22: Pathology of Pulmonary Arterial HypertensionByPeter DorfmüllerPeter DorfmüllerService d’Anatomie et de Cytologie Pathologiques, Hôpital Marie Lannelongue and INSERM U999 ‘Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique’, Le Plessis Robinson, FranceSearch for other works by this author on:
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23 - 36: Invasive Rest and Exercise Hemodynamics in the Modern Management of Pulmonary Vascular Disease: An Expanding Role in the FutureByKenneth F. Whyte;Kenneth F. WhyteaGreenlane Respiratory Service, Auckland City Hospital, Auckland, New Zealand;Search for other works by this author on:Philipe Hervé;Philipe HervébDepartment of Thoracic and Vascular Surgery, Marie Lannelongue Hospital, Le Plessis-Robinson, andSearch for other works by this author on:Susanna Hoette;Susanna HoettecService de Pneumologie, Hospital Antoine Béclère, Clamart, FranceSearch for other works by this author on:Denis ChemlaDenis ChemlacService de Pneumologie, Hospital Antoine Béclère, Clamart, FranceSearch for other works by this author on:
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37 - 47: Exercise Testing in Pulmonary Arterial HypertensionBySteeve Provencher;Steeve ProvencherCentre de recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, CanadaSearch for other works by this author on:Vincent MainguyVincent MainguyCentre de recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, CanadaSearch for other works by this author on:
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48 - 58: Noninvasive Exploration of the Pulmonary Circulation and the Right HeartByAnton Vonk Noordegraa;Anton Vonk NoordegraaaDepartment of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands;Search for other works by this author on:Andrew Peacock;Andrew PeacockbScottish Pulmonary Vascular Unit, Regional Heart and Lung Centre, Glasgow, UK;Search for other works by this author on:Robert NaeijeRobert NaeijecDepartment of Cardiology, Erasme University, Brussels, BelgiumSearch for other works by this author on:
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59 - 64: Biomarkers in Pulmonary Arterial HypertensionByRogerio Souza;Rogerio SouzaPulmonary Circulation Unit, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Susana Hoette;Susana HoettePulmonary Circulation Unit, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Bruno Dias;Bruno DiasPulmonary Circulation Unit, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Carlos JardimCarlos JardimPulmonary Circulation Unit, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:
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65 - 75: Genetics of Pulmonary Arterial Hypertension and the Concept of Heritable Pulmonary Arterial HypertensionByBarbara Girerd;Barbara GirerdaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Service de Pneumologie et Réanimation Respiratoire, Centre de Référence de l’Hypertension Pulmonaire Sévère, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, andSearch for other works by this author on:David Montani;David MontaniaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Service de Pneumologie et Réanimation Respiratoire, Centre de Référence de l’Hypertension Pulmonaire Sévère, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, andSearch for other works by this author on:Azzedine Yaici;Azzedine YaiciaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Service de Pneumologie et Réanimation Respiratoire, Centre de Référence de l’Hypertension Pulmonaire Sévère, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, andSearch for other works by this author on:Mélanie Eyries;Mélanie EyriesdLaboratoire d’Oncogénétique et Angiogénétique Moléculaire, Groupe Hospitalier Pitié-Salpétrière, UMRS 956 INSERM, Université Pierre et Marie Curie-Paris 6, Paris, FranceSearch for other works by this author on:Florence Coulet;Florence CouletdLaboratoire d’Oncogénétique et Angiogénétique Moléculaire, Groupe Hospitalier Pitié-Salpétrière, UMRS 956 INSERM, Université Pierre et Marie Curie-Paris 6, Paris, FranceSearch for other works by this author on:Florent Soubrier;Florent SoubrierdLaboratoire d’Oncogénétique et Angiogénétique Moléculaire, Groupe Hospitalier Pitié-Salpétrière, UMRS 956 INSERM, Université Pierre et Marie Curie-Paris 6, Paris, FranceSearch for other works by this author on:Marc HumbertMarc HumbertaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Service de Pneumologie et Réanimation Respiratoire, Centre de Référence de l’Hypertension Pulmonaire Sévère, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, andSearch for other works by this author on:
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76 - 84: Drug- and Toxin-Induced Pulmonary Arterial HypertensionByLaura Price;Laura PriceaRoyal Brompton Hospital, Department of Critical Care, National Heart and Lung Institute, andSearch for other works by this author on:Kim Bouillon;Kim BouillonbUniversity College London, Department of Epidemiology and Public Health, London, UK;Search for other works by this author on:S. John Wort;S. John WortaRoyal Brompton Hospital, Department of Critical Care, National Heart and Lung Institute, andSearch for other works by this author on:Marc HumbertMarc HumbertcUniversité Paris-Sud 11, Centre National de Référence de l’Hypertension Artérielle Pulmonaire, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine-Béclère, Assistance Publique, Hôpitaux de Paris, Clamart, FranceSearch for other works by this author on:
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85 - 93: Idiopathic Pulmonary Arterial Hypertension and Its Prognosis in the Modern Management Era in Developed and Developing CountriesByXin Jiang;Xin JiangaDepartment of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, PR China;Search for other works by this author on:Marc Humbert;Marc HumbertbUniversité Paris-Sud, Faculté de Médecine, Le Kremlin-Bicêtre, Service de Pneumologie, Hôpital Antoine Béclère, Assistance-Publique Hôpitaux de Paris, Clamart, INSERM U999, Clamart, FranceSearch for other works by this author on:Zhi-Cheng JingZhi-Cheng JingaDepartment of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, PR China;Search for other works by this author on:
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94 - 104: Pulmonary Arterial Hypertension Complicating Connective Tissue DisordersByJérôme Le Pavec;Jérôme Le PavecaUniversité Paris-Sud 11, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Assistance Publique Hôpitaux de Paris, Clamart, France;Search for other works by this author on:Paul M. HassounPaul M. HassounbDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Md., USASearch for other works by this author on:
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105 - 112: Pulmonary Arterial Hypertension and HIV and Other Viral InfectionsBySéverine Valmary;Séverine ValmarybPathology, CHU Jean Minjoz, Besançon,Search for other works by this author on:Olivier Sitbon;Olivier SitboncDepartment of Pneomonology, Hôpital Antoine Béclère, Clamart, FranceSearch for other works by this author on:Marc HumbertMarc HumbertcDepartment of Pneomonology, Hôpital Antoine Béclère, Clamart, FranceSearch for other works by this author on:
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113 - 121: Portopulmonary Hypertension and Hepatopulmonary SyndromeByLaurent Savale;Laurent SavaleaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson, FranceSearch for other works by this author on:Philippe Hervé;Philippe HervéaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson, FranceSearch for other works by this author on:Olivier SitbonOlivier SitbonaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson, FranceSearch for other works by this author on:
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122 - 136: Pulmonary Hypertension in Congenital Heart DiseasesByCecile Tissot;Cecile TissotPediatric Cardiology Unit, The University Children’s Hospital of Geneva, Geneva, SwitzerlandSearch for other works by this author on:Maurice BeghettiMaurice BeghettiPediatric Cardiology Unit, The University Children’s Hospital of Geneva, Geneva, SwitzerlandSearch for other works by this author on:
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137 - 142: Pulmonary Hypertension in Sickle Cell DiseaseByFlorence Parent;Florence ParentaCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,bUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson,Search for other works by this author on:Laurent Savale;Laurent SavaleaCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,bUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson,Search for other works by this author on:Bernard Maitre;Bernard MaitredService de Pneumologie, hôpitaux intercommunal et H Mondor, Créteil,eInserm U955 IMRB, Unité des Maladies Génétiques du Globule Rouge, hôpital H Mondor, Créteil, FranceSearch for other works by this author on:Gérald SimonneauGérald SimonneauaCentre de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère (AP-HP), Clamart,bUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Le Plessis Robinson,Search for other works by this author on:
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143 - 148: Schistosomiasis and Pulmonary HypertensionByCaio Julio Cesar Fernandes;Caio Julio Cesar FernandesPulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Carlos Jardim;Carlos JardimPulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Andre Hovnanian;Andre HovnanianPulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Susana Hoette;Susana HoettePulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Luciana Kato Morinaga;Luciana Kato MorinagaPulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:Rogerio SouzaRogerio SouzaPulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, BrazilSearch for other works by this author on:
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149 - 160: Pulmonary Veno-Occlusive DiseaseByDavid Montani;David MontaniaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:Alice Huertas;Alice HuertasaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:Peter Dorfmüller;Peter DorfmülleraUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:Marc HumbertMarc HumbertaUniversité Paris-Sud, Faculté de Médecine, Kremlin-Bicêtre,bAP-HP, Centre National de Référence de l’Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Antoine Béclère, Clamart,cINSERM U999, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, FranceSearch for other works by this author on:
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161 - 168: Pulmonary Hypertension and Left Heart DiseaseByYochai Adir;Yochai AdiraPulmonary Division, Carmel Medical Center, Faculty of Medicine, Technion, Institute of Technology, Haifa, Israel;Search for other works by this author on:Nazzareno GalièNazzareno GalièbInstitute of Cardiology, University of Bologna, Bologna, ItalySearch for other works by this author on:
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169 - 177: Pulmonary Hypertension in Chronic Obstructive Pulmonary DiseaseByEmmanuel Weitzenblum;Emmanuel WeitzenblumaDepartment of Pulmonology, Nouvel Hôpital Civil, Strasbourg,Search for other works by this author on:Ari Chaouat;Ari ChaouatbDepartment of Respiratory Diseases and Respiratory Intensive Care, CHU de Nancy, Vandoeuvre les Nancy, Nancy, FranceSearch for other works by this author on:Matthieu Canuet;Matthieu CanuetaDepartment of Pulmonology, Nouvel Hôpital Civil, Strasbourg,Search for other works by this author on:Alain Ducoloné;Alain DucolonéaDepartment of Pulmonology, Nouvel Hôpital Civil, Strasbourg,Search for other works by this author on:Romain KesslerRomain KessleraDepartment of Pulmonology, Nouvel Hôpital Civil, Strasbourg,Search for other works by this author on:
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178 - 198: Pulmonary Hypertension Complicating Interstitial and Granulomatous Lung DiseasesByHilario Nunes;Hilario NunesaUniversity Paris 13, UPRES EA 2363, Assistance Publique Hôpitaux de Paris, Avicenne Hospital and Departments of Pneumology,Search for other works by this author on:Yurdagul Uzunhan;Yurdagul UzunhanaUniversity Paris 13, UPRES EA 2363, Assistance Publique Hôpitaux de Paris, Avicenne Hospital and Departments of Pneumology,Search for other works by this author on:Thomas Gille;Thomas GilleaUniversity Paris 13, UPRES EA 2363, Assistance Publique Hôpitaux de Paris, Avicenne Hospital and Departments of Pneumology,Search for other works by this author on:Gaelle Dauriat;Gaelle DauriatdAssistance Publique Hôpitaux de Paris, Bichat Hospital, Departement of Pneumology, Paris, FranceSearch for other works by this author on:Marianne Kambouchner;Marianne KambouchnercPathology, Bobigny, andSearch for other works by this author on:Dominique VaeyreDominique VaeyreaUniversity Paris 13, UPRES EA 2363, Assistance Publique Hôpitaux de Paris, Avicenne Hospital and Departments of Pneumology,Search for other works by this author on:
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199 - 206: High-Altitude Pulmonary HypertensionByRuo-Min Di;Ruo-Min DiDepartment of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, PR ChinaSearch for other works by this author on:Zhi-Cheng JingZhi-Cheng JingDepartment of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, PR ChinaSearch for other works by this author on:
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207 - 217: Acute Pulmonary Venous Thromboembolic DiseaseByOlivier Sanchez;Olivier SanchezaUniversité Paris Descartes, Sorbonne Paris Cité,bService de Pneumologie et Soins Intensifs, Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris, FranceSearch for other works by this author on:Guy MeyerGuy MeyeraUniversité Paris Descartes, Sorbonne Paris Cité,bService de Pneumologie et Soins Intensifs, Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris, FranceSearch for other works by this author on:
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218 - 225: Anticoagulation for Venous Thromboembolism in the Modern Management EraByGrégoire Le Gal;Grégoire Le GalaEA3878 (GETBO) IFR 148, Université de Brest,bDépartement de médecine interne et de pneumologie, CHU de la Cavale Blanche, Brest, FranceSearch for other works by this author on:Christophe Leroyer;Christophe LeroyeraEA3878 (GETBO) IFR 148, Université de Brest,bDépartement de médecine interne et de pneumologie, CHU de la Cavale Blanche, Brest, FranceSearch for other works by this author on:Dominique MottierDominique MottieraEA3878 (GETBO) IFR 148, Université de Brest,bDépartement de médecine interne et de pneumologie, CHU de la Cavale Blanche, Brest, FranceSearch for other works by this author on:
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226 - 236: Chronic Thromboembolic Pulmonary HypertensionByIrene M. Lang;Irene M. LangaMedical University of Vienna, Vienna, Austria;Search for other works by this author on:Xavier JaisXavier JaisbUniversity Paris Sud (Paris XI), INSERM U 999, Hôpital Antoine Béclère, Clamart, FranceSearch for other works by this author on:
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237 - 245: Medical Treatment of Pulmonary Arterial HypertensionByDermot S. O’Callaghan;Dermot S. O’CallaghanaService de Pneumologie et Réanimation Respiratoire, Centre National de Référence de l’Hypertension Artérielle Pulmonaire Sévère, Hôpital Antoine Béclère, Assistance Publique Hôpitaux de Paris, Université Paris-Sud 11, Clamart, France;Search for other works by this author on:Sean P. GaineSean P. GainebNational Pulmonary Hypertension Unit, Department of Respiratory Medicine, Mater Misericordiae University Hospital, University College Dublin, Dublin, IrelandSearch for other works by this author on:
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246 - 253: Lung Transplantation and Role for Novel Extracorporeal Support in Pulmonary HypertensionByMarius M. HoeperMarius M. HoeperHannover Medical School, Department of Respiratory Medicine, Hannover, GermanySearch for other works by this author on:
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254 - 261: Atrial SeptostomyByJean-Luc VachiéryJean-Luc VachiéryClinique de l’Hypertension Pulmonaire et de l’Insuffisance Cardiaque, Service de Cardiologie, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Brussels, BelgiumSearch for other works by this author on:
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262 - 275: Pulmonary Vascular Disorders in Hereditary Hemorrhagic TelangiectasiaByVincent Cottin;Vincent CottinaHospices Civils de Lyon, Hôpital Louis Pradel, Service de Pneumologie, Centre de référence national des maladies pulmonaires rares, Université de Lyon, Université Lyon I, INRA, UMR754 INRA-Vetagrosup EPHE IFR 128,cCentre de référence national de la maladie de Rendu-Osler; Research Network on Rendu-Osler Disease, Lyon, FranceSearch for other works by this author on:Chahéra Khouatra;Chahéra KhouatraaHospices Civils de Lyon, Hôpital Louis Pradel, Service de Pneumologie, Centre de référence national des maladies pulmonaires rares, Université de Lyon, Université Lyon I, INRA, UMR754 INRA-Vetagrosup EPHE IFR 128,cCentre de référence national de la maladie de Rendu-Osler; Research Network on Rendu-Osler Disease, Lyon, FranceSearch for other works by this author on:Sophie Dupuis-Girod;Sophie Dupuis-GirodbHospices Civils de Lyon, Hôpital Louis Pradel, Service de génétique, andcCentre de référence national de la maladie de Rendu-Osler; Research Network on Rendu-Osler Disease, Lyon, FranceSearch for other works by this author on:Jean-François CordierJean-François CordieraHospices Civils de Lyon, Hôpital Louis Pradel, Service de Pneumologie, Centre de référence national des maladies pulmonaires rares, Université de Lyon, Université Lyon I, INRA, UMR754 INRA-Vetagrosup EPHE IFR 128,cCentre de référence national de la maladie de Rendu-Osler; Research Network on Rendu-Osler Disease, Lyon, FranceSearch for other works by this author on:
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276 - 279: Future Perspectives in Pulmonary Arterial HypertensionByLewis J. RubinLewis J. RubinDivision of Pulmonary and Critical Care Medicine, School of Medicine, University of California at San Diego, La Jolla, Calif., USASearch for other works by this author on: