Inflammation in Psychiatry
Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.
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1 - 19: Basic Aspects of the Immunology of NeuroinflammationByEric S. Wohleb;Eric S. WohlebDepartment of Neuroscience, Institute for Behavioral Medicine Research, Center for Brain and Spinal Cord Repair, The Ohio State University, Columbus, Ohio, USASearch for other works by this author on:Jonathan P. GodboutJonathan P. GodboutDepartment of Neuroscience, Institute for Behavioral Medicine Research, Center for Brain and Spinal Cord Repair, The Ohio State University, Columbus, Ohio, USASearch for other works by this author on:
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20 - 32: Stress and NeuroinflammationByAngela J. Grippo;Angela J. GrippoaDepartment of Psychology, Northern Illinois University, DeKalb, Ill., andSearch for other works by this author on:Melissa-Ann L. ScottiMelissa-Ann L. ScottiaDepartment of Psychology, Northern Illinois University, DeKalb, Ill., andbDepartment of Psychiatry and Brain-Body Center, University of Illinois at Chicago, Chicago, Ill., USASearch for other works by this author on:
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33 - 48: Role of Inflammation in Depression: Implications for Phenomenology, Pathophysiology and TreatmentByCharles L. Raison;Charles L. RaisonaDepartment of Psychiatry, College of Medicine, John and Doris Norton School of Family and Consumer Sciences, University of Arizona, Tucson, Ariz., andSearch for other works by this author on:Andrew H. MillerAndrew H. MillerbDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Ga., USASearch for other works by this author on:
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49 - 60: Virus Infection as a Cause of Inflammation in Psychiatric DisordersByKarl BechterKarl BechterBezirkskrankenhaus, Abteilung für Psychotherapie und Psychosomatik, Ulm University, Günzburg, GermanySearch for other works by this author on:
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61 - 74: Inflammation, Neurotoxins and Psychiatric DisordersByAye-Mu MyintAye-Mu MyintPsychiatric Hospital, Ludwig-Maximilians University, Munich, GermanySearch for other works by this author on:
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75 - 89: Essential Fatty Acids as Potential Anti-Inflammatory Agents in the Treatment of Affective DisordersByCai SongCai SongaChinese Academy Engineering Institute for the Development of Endangered Medicinal Resources in Southwest China, Guangxi Botanic Garden of Medicinal Plants, Nanning, Guangxi, PR China;bDepartment of Psychology, Dalhousie University, Halifax, N.S., CanadaSearch for other works by this author on:
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90 - 99: The Brain-Gut Axis: A Target for Treating Stress-Related DisordersByLucinda V. Scott;Lucinda V. ScottDepartment of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, IrelandSearch for other works by this author on:Gerard Clarke;Gerard ClarkeDepartment of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, IrelandSearch for other works by this author on:Timothy G. DinanTimothy G. DinanDepartment of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, IrelandSearch for other works by this author on:
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100 - 116: The Question of Pro-Inflammatory Immune Activity in Schizophrenia and the Potential Importance of Anti-Inflammatory DrugsByVolker Arolt;Volker AroltDepartment of Psychiatry, University of Münster, Münster, GermanySearch for other works by this author on:Oliver AmbréeOliver AmbréeDepartment of Psychiatry, University of Münster, Münster, GermanySearch for other works by this author on:
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117 - 126: Inflammation as the Cause of the Metabolic Syndrome in DepressionByBrian E. LeonardBrian E. LeonardPharmacology Department, National University of Ireland, Galway, Ireland; Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany; European School of Neuroscience, Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The NetherlandsSearch for other works by this author on:
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127 - 143: Glucocorticoids and Inflammation: A Double-Headed Sword in Depression?: How Do Neuroendocrine and Inflammatory Pathways Interact during Stress to Contribute to the Pathogenesis of Depression?ByM.A. Horowitz;M.A. HorowitzaDepartment of Psychological Medicine, Section of Perinatal Psychiatry and Stress, Psychiatry and Immunology (SPI-lab), Institute of Psychiatry, King's College London,Search for other works by this author on:P.A. Zunszain;P.A. ZunszainaDepartment of Psychological Medicine, Section of Perinatal Psychiatry and Stress, Psychiatry and Immunology (SPI-lab), Institute of Psychiatry, King's College London,bInstitute of Psychiatry and South London and Maudsley NHS Foundation Trust, National Institute for Health Research ‘Biomedical Research Centre for Mental Health' andSearch for other works by this author on:C. Anacker;C. AnackeraDepartment of Psychological Medicine, Section of Perinatal Psychiatry and Stress, Psychiatry and Immunology (SPI-lab), Institute of Psychiatry, King's College London,bInstitute of Psychiatry and South London and Maudsley NHS Foundation Trust, National Institute for Health Research ‘Biomedical Research Centre for Mental Health' andcCentre for the Cellular Basis of Behaviour, Institute of Psychiatry, King's College London, London, UKSearch for other works by this author on:K. Musaelyan;K. MusaelyanaDepartment of Psychological Medicine, Section of Perinatal Psychiatry and Stress, Psychiatry and Immunology (SPI-lab), Institute of Psychiatry, King's College London,Search for other works by this author on:C.M. ParianteC.M. ParianteaDepartment of Psychological Medicine, Section of Perinatal Psychiatry and Stress, Psychiatry and Immunology (SPI-lab), Institute of Psychiatry, King's College London,bInstitute of Psychiatry and South London and Maudsley NHS Foundation Trust, National Institute for Health Research ‘Biomedical Research Centre for Mental Health' andSearch for other works by this author on:
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144 - 161: Co-Morbidity between Cardiovascular Pathology and Depression: Role of InflammationByAngelos HalarisAngelos HalarisDepartment of Psychiatry and Behavioral Neuroscience, Loyola University Stritch School of Medicine, and Loyola University Medical Center, Maywood, Ill., USASearch for other works by this author on:
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162 - 174: Inflammatory and Oxidative and Nitrosative Stress Cascades as New Drug Targets in Myalgic Encephalomyelitis and Chronic Fatigue SyndromeByMichael MaesMichael MaesMaes Clinics @ TRIA, Piyavate Hospital, Bangkok, ThailandSearch for other works by this author on:
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175 - 187: Peripheral Inflammation and Cognitive AgingByAlvin Lim;Alvin LimDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pa., USASearch for other works by this author on:Katarina Krajina;Katarina KrajinaDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pa., USASearch for other works by this author on:Anna L. MarslandAnna L. MarslandDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pa., USASearch for other works by this author on:
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188 - 202: Inflammation in Suicidality: Implications for Novel Treatment OptionsByShorena Janelidze;Shorena JanelidzeaPsychoimmunology Unit, Section for Psychiatry, Department of Clinical Sciences, Lund University, Lund, Sweden;Search for other works by this author on:Lena BrundinLena BrundinaPsychoimmunology Unit, Section for Psychiatry, Department of Clinical Sciences, Lund University, Lund, Sweden;bDepartment of Translational Science and Molecular Medicine, Michigan State University, Grand Rapids, Mich., USASearch for other works by this author on: