Adipose Tissue Development: From Animal Models to Clinical Conditions3rd ESPE Advanced Seminar in Developmental Endocrinology, Paris, March 2009
Nowadays, adipose tissue is not only regarded as an organ of storage related to fuel metabolism but also as an endocrine organ involved in the regulation of insulin sensitivity, lipids and energy metabolism. These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed. Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition.
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1 - 20: Human Lipodystrophies: Genetic and Acquired Diseases of Adipose TissueByJacqueline Capeau;Jacqueline CapeauaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andcAP-HP Tenon and Saint-Antoine Hospitals, Paris, FranceSearch for other works by this author on:Jocelyne Magré;Jocelyne MagréaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andSearch for other works by this author on:Martine Caron-Debarle;Martine Caron-DebarleaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andSearch for other works by this author on:Claire Lagathu;Claire LagathuaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andSearch for other works by this author on:Bénédicte Antoine;Bénédicte AntoineaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andSearch for other works by this author on:Vé;ronique Béréziat;Vé;ronique BéréziataINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andSearch for other works by this author on:Olivier Lascols;Olivier LascolsaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andcAP-HP Tenon and Saint-Antoine Hospitals, Paris, FranceSearch for other works by this author on:Jean-Philippe Bastard;Jean-Philippe BastardaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andcAP-HP Tenon and Saint-Antoine Hospitals, Paris, FranceSearch for other works by this author on:Corinne VigourouxCorinne VigourouxaINSERM, U938, CDR Saint-Antoine;bUPMC University Paris 06, UMR_S938 andcAP-HP Tenon and Saint-Antoine Hospitals, Paris, FranceSearch for other works by this author on:
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21 - 30: The Emergence of AdipocytesByPatrick Laharrague;Patrick LaharragueaLaboratoire d’Hématologie, CHU Toulouse, Hôpital Rangueil etbMétabolisme, Plasticité et Mitochondrie, Université de Toulouse, Toulouse, FranceSearch for other works by this author on:Louis CasteillaLouis CasteillabMétabolisme, Plasticité et Mitochondrie, Université de Toulouse, Toulouse, FranceSearch for other works by this author on:
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31 - 44: Adipose Tissue and the Reproductive Axis: Biological AspectsByG.J. Hausman;G.J. HausmanUSDA/ARS, Richard B. Russell Agriculture Research Center, Athens, Ga., USASearch for other works by this author on:C.R. BarbC.R. BarbUSDA/ARS, Richard B. Russell Agriculture Research Center, Athens, Ga., USASearch for other works by this author on:
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45 - 52: Unraveling the Obesity and Breast Cancer Links: A Role for Cancer-Associated Adipocytes?ByBé;atrice Dirat;Bé;atrice DirataUniversity of Toulouse,bInstitute of Pharmacology and Structural Biology CNRS UMR 5089,cInstitut National de la Santé et de la Recherche médicale, INSERM U858 Equipe 3, IFR31, andSearch for other works by this author on:Ludivine Bochet;Ludivine BochetaUniversity of Toulouse,bInstitute of Pharmacology and Structural Biology CNRS UMR 5089,cInstitut National de la Santé et de la Recherche médicale, INSERM U858 Equipe 3, IFR31, andSearch for other works by this author on:Ghislaine Escourrou;Ghislaine EscourroudDepartment of Anatompathology and Cytology, CHU Rangueil, Toulouse, FranceSearch for other works by this author on:Philippe Valet;Philippe ValetaUniversity of Toulouse,cInstitut National de la Santé et de la Recherche médicale, INSERM U858 Equipe 3, IFR31, andSearch for other works by this author on:Catherine MullerCatherine MulleraUniversity of Toulouse,bInstitute of Pharmacology and Structural Biology CNRS UMR 5089,Search for other works by this author on:
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53 - 61: Early Determinants of ObesityByKen K. OngKen K. OngMRC Epidemiology Unit, Cambridge, UKSearch for other works by this author on:
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62 - 72: Metabolic Syndrome in Childhood – Causes and EffectsByRam WeissRam WeissHebrew University-Hadassah Braun School of Public Health and Community Medicine, Faculty of Medicine, Jerusalem, IsraelSearch for other works by this author on:
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73 - 83: Pathophysiology of Insulin Resistance in Small for Gestational Age Subjects: A Role for Adipose Tissue?ByJacques Beltrand;Jacques BeltrandINSERM, U690 and Université Paris 7 Denis Diderot, Paris, FranceSearch for other works by this author on:Taly Meas;Taly MeasINSERM, U690 and Université Paris 7 Denis Diderot, Paris, FranceSearch for other works by this author on:Claire Levy-MarchalClaire Levy-MarchalINSERM, U690 and Université Paris 7 Denis Diderot, Paris, FranceSearch for other works by this author on:
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84 - 92: The Neural Feedback Loop between the Brain and Adipose TissuesByLuc PénicaudLuc PénicaudUMR 6265, CNRS Université de Bourgogne, Dijon, FranceSearch for other works by this author on: