Personalized Nutrition: Translating Nutrigenetic/Nutrigenomic Research into Dietary Guidelines
Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the ‘3rd Congress of the International Society of Nutrigenetics/Nutrigenomics’ held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work.
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1 - 7: Opportunities and Challenges in Nutrigenetics/Nutrigenomics and HealthByRaffaele De CaterinaRaffaele De CaterinaG. d’Annunzio University, Chieti and CNR Institute of Clinical Physiology, Pisa, ItalySearch for other works by this author on:
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8 - 14: Genome-Wide Association Studies and DietByLynnette R. FergusonLynnette R. FergusonDiscipline of Nutrition, FM & HS, University of Auckland, and Nutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on:
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15 - 20: Copy Number Variation, Eicosapentaenoic Acid and Neurological Disorders. With Particular Reference to Huntington's Disease and Associated CAG Repeats, and to Myalgic Encephalomyelitis and Viral Infection: With Particular Reference to Huntington’s Disease and Associated CAG Repeats, and to Myalgic Encephalomyelitis and Viral InfectionByBasant K. Puri;Basant K. PuriaMRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, andSearch for other works by this author on:Mehar S. MankuMehar S. MankubAmarin Neuroscience, Oxford, UKSearch for other works by this author on:
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21 - 33: Nutrigenetics: A Tool to Provide Personalized Nutritional Therapy to the ObeseByAmelia Marti;Amelia MartiInstitute of Nutrition and Food Sciences, University of Navarra, Pamplona, SpainSearch for other works by this author on:Estibaliz Goyenechea;Estibaliz GoyenecheaInstitute of Nutrition and Food Sciences, University of Navarra, Pamplona, SpainSearch for other works by this author on:J. Alfredo MartínezJ. Alfredo MartínezInstitute of Nutrition and Food Sciences, University of Navarra, Pamplona, SpainSearch for other works by this author on:
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34 - 45: Xenobiotic Metabolizing Genes, Meat-Related Exposures, and Risk of Advanced Colorectal AdenomaByLeah M. Ferrucci;Leah M. FerrucciaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,bYale School of Public Health, New Haven, Conn.,Search for other works by this author on:Amanda J. Cross;Amanda J. CrossaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Marc J. Gunter;Marc J. GuntercDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, andSearch for other works by this author on:Jiyoung Ahn;Jiyoung AhndDivision of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, N.Y, USASearch for other works by this author on:Susan T. Mayne;Susan T. MaynebYale School of Public Health, New Haven, Conn.,Search for other works by this author on:Xiaomei Ma;Xiaomei MabYale School of Public Health, New Haven, Conn.,Search for other works by this author on:Stephen J. Chanock;Stephen J. ChanockaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Meredith Yeager;Meredith YeageraDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Barry I. Graubard;Barry I. GraubardaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Sonja I. Berndt;Sonja I. BerndtaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Wen-Yi Huang;Wen-Yi HuangaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:Richard B. Hayes;Richard B. HayesdDivision of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, N.Y, USASearch for other works by this author on:Rashmi SinhaRashmi SinhaaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Md.,Search for other works by this author on:
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46 - 55: Strategies to Improve Detection of Hypertension GenesBySteven C. HuntSteven C. HuntCardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USASearch for other works by this author on:
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56 - 72: Diet, Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult DiseaseByAlan A. Jackson;Alan A. JacksonaInstitute of Human Nutrition, University of Southampton School of Medicine, Southampton General Hospital,bNational Institutes of Health Research, Nutrition Biomedical Research Unit, Southampton Universities NHS Trust, Southampton General Hospital,Search for other works by this author on:Graham C. Burdge;Graham C. BurdgeaInstitute of Human Nutrition, University of Southampton School of Medicine, Southampton General Hospital,Search for other works by this author on:Karen A. LillycropKaren A. LillycropbNational Institutes of Health Research, Nutrition Biomedical Research Unit, Southampton Universities NHS Trust, Southampton General Hospital,cDevelopmental and Cell Biology, University of Southampton School of Biological Sciences, Southampton, UKSearch for other works by this author on:
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73 - 83: Choline: Clinical Nutrigenetic/Nutrigenomic Approaches for Identification of Functions and Dietary RequirementsBySteven H. ZeiselSteven H. ZeiselNutrition Research Institute, Department of Nutrition, School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, N.C., USASearch for other works by this author on:
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84 - 94: Dietary Polyphenols, Deacetylases and Chromatin Remodeling in InflammationByIrfan Rahman;Irfan RahmanDepartment of Environmental Medicine, Lung Biology and Disease Program, University of Rochester Medical Center, Rochester, N.Y., USASearch for other works by this author on:Sangwoon ChungSangwoon ChungDepartment of Environmental Medicine, Lung Biology and Disease Program, University of Rochester Medical Center, Rochester, N.Y., USASearch for other works by this author on:
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95 - 102: Dietary Manipulation of Histone Structure and FunctionByEmily Ho;Emily HoaDepartment of Nutrition and Exercise Sciences,bLinus Pauling Institute,Search for other works by this author on:Roderick H. DashwoodRoderick H. DashwoodbLinus Pauling Institute,cDepartment of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oreg., USASearch for other works by this author on:
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103 - 114: Changes in Human Adipose Tissue Gene Expression during Diet-Induced Weight LossByPer-Arne Svensson;Per-Arne SvenssonSahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, SwedenSearch for other works by this author on:Anders Gummesson;Anders GummessonSahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, SwedenSearch for other works by this author on:Lena M.S. Carlsson;Lena M.S. CarlssonSahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, SwedenSearch for other works by this author on:Kajsa SjöholmKajsa SjöholmSahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, SwedenSearch for other works by this author on:
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115 - 122: Toxicogenomics and Studies of Genomic Effects of Dietary ComponentsByKarol ThompsonKarol ThompsonCenter for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Md., USASearch for other works by this author on:
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123 - 130: Dietary Methyl Deficiency, microRNA Expression and Susceptibility to Liver CarcinogenesisByAthena Starlard-Davenport;Athena Starlard-DavenportaDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Ariz.,Search for other works by this author on:Volodymyr Tryndyak;Volodymyr TryndyakaDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Ariz.,Search for other works by this author on:Oksana Kosyk;Oksana KosykbDepartment of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, N.C., andSearch for other works by this author on:Sharon R. Ross;Sharon R. RosscDivision of Cancer Prevention, National Cancer Institute, Bethesda, Md., USASearch for other works by this author on:Ivan Rusyn;Ivan RusynbDepartment of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, N.C., andSearch for other works by this author on:Frederick A. Beland;Frederick A. BelandaDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Ariz.,Search for other works by this author on:Igor P. PogribnyIgor P. PogribnyaDivision of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Ariz.,Search for other works by this author on:
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131 - 153: Redox Dysregulation and Oxidative Stress in Schizophrenia: Nutrigenetics as a Challenge in Psychiatric Disease PreventionByKim Q. Do;Kim Q. DoaDepartment of Psychiatry,bCenter for Psychiatric Neuroscience, andSearch for other works by this author on:Philippe Conus;Philippe ConusaDepartment of Psychiatry,cService of General Psychiatry, Lausanne University Hospital, Lausanne, SwitzerlandSearch for other works by this author on:Michel CuenodMichel CuenodaDepartment of Psychiatry,bCenter for Psychiatric Neuroscience, andSearch for other works by this author on:
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154 - 159: Nutrigenomics and Agriculture: A PerspectiveByJoseph T. SpenceJoseph T. SpenceBeltsville Agricultural Research Center, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, Md., USASearch for other works by this author on:
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160 - 168: Opportunities and Challenges in Nutrigenetics/Nutrigenomics: Building Industry-Academia PartnershipsByPeter J. Gillies;Peter J. GilliesaDuPont Applied BioSciences, Wilmington, De., andSearch for other works by this author on:Penny M. Kris-EthertonPenny M. Kris-EthertonbThe Pennsylvania State University, University Park, Pa., USASearch for other works by this author on:
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169 - 175: Tailoring Foods to Match People's Genes in New Zealand: Opportunities for CollaborationByLynnette R. Ferguson;Lynnette R. FergusonaDiscipline of Nutrition andcNutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on:Rong Hu;Rong HuaDiscipline of Nutrition andcNutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on:Wen Jiun Lam;Wen Jiun LamaDiscipline of Nutrition andcNutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on:Karen Munday;Karen MundayaDiscipline of Nutrition andcNutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on:Christopher M. TriggsChristopher M. TriggsbDepartment of Statistics, The University of Auckland, andcNutrigenomics New Zealand, Auckland, New ZealandSearch for other works by this author on: