Metabolic Effects of Psychotropic DrugsAvailable to Purchase
Major depression and bipolar disorder are chronic enduring serious mental illnesses (SMI) with devastating effects on psychosocial functioning and may culminate in suicide. Over the past years, it has become apparent that subjects with these conditions can also develop the metabolic syndrome, which is a series of obesity-related physical conditions with an endocrine basis. This book brings together reviews that help put into context exactly why subjects with SMI develop obesity, prediabetic status, overt type 2 diabetes mellitus and related cardiovascular events. The relationship between prolactin and bone mineral density in subjects under medical treatment and the underlying dopaminergic mechanisms as well as the immunological changes occurring as an integral part of SMI and their effects on endocrine function are discussed and reviewed.
Psychiatrists, diabetologists, cardiologists, family practitioners, public health physicians as well as basic science researchers will find valuable guidelines when screening for type 2 diabetes mellitus and cardiovascular disease in SMI.
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Table of Contents
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1 - 11: Metabolic Syndrome and Schizophrenia: Is Inflammation the Cause?ByBrian E. LeonardBrian E. LeonardaPharmacology Department, National University of Ireland, Galway, Ireland;bDepartment of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, GermanySearch for other works by this author on:
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12 - 24: Insulin Resistance in Bipolar Women: Effects of Mood-Stabilizing DrugsByMytilee Vemuri;Mytilee VemuriDepartment of Psychiatry, Stanford University, Stanford, Calif., USASearch for other works by this author on:Pascale Stemmle;Pascale StemmleDepartment of Psychiatry, Stanford University, Stanford, Calif., USASearch for other works by this author on:Bowen Jiang;Bowen JiangDepartment of Psychiatry, Stanford University, Stanford, Calif., USASearch for other works by this author on:Anna Morenkova;Anna MorenkovaDepartment of Psychiatry, Stanford University, Stanford, Calif., USASearch for other works by this author on:Natalie RasgonNatalie RasgonDepartment of Psychiatry, Stanford University, Stanford, Calif., USASearch for other works by this author on:
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25 - 46: Obesity and Mental IllnessByLeslie Citromea;Leslie CitromeaaNew York University School of Medicine, Department of Psychiatry, and the Nathan S. Kline Institute for Psychiatric Research, Orangeburg, N.Y.; bUniversity Behavioral HealthCare, the School of Nursing, and the Departments of Psychiatry and Family Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, N.J., USASearch for other works by this author on:Betty VreelandbBetty VreelandbaNew York University School of Medicine, Department of Psychiatry, and the Nathan S. Kline Institute for Psychiatric Research, Orangeburg, N.Y.; bUniversity Behavioral HealthCare, the School of Nursing, and the Departments of Psychiatry and Family Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, N.J., USASearch for other works by this author on:
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47 - 65: Glucose Abnormalities in Schizophrenia, Bipolar and Major Depressive DisordersByChris BusheChris BusheEli Lilly and Company, Basingstoke, UKSearch for other works by this author on:
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66 - 81: Screening for Diabetes and Cardiovascular Risk Factors in People with Serious Mental IllnessByRichard I.G. Holt;Richard I.G. HoltaEndocrinology and Metabolism Sub-division, Developmental Origins of Health and Disease Division, andSearch for other works by this author on:Robert C. PevelerRobert C. PevelerbClinical Neurosciences Division, School of Medicine, University of Southampton, Southampton, UKSearch for other works by this author on:
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82 - 89: Stress Axis Dysfunction: A Common Finding in Schizophrenia and the Metabolic Syndrome?ByNatasha Afzal;Natasha AfzalNeuroscience Centre, St. Vincent’s Hospital Fairview, Dublin, IrelandSearch for other works by this author on:Jogin ThakoreJogin ThakoreNeuroscience Centre, St. Vincent’s Hospital Fairview, Dublin, IrelandSearch for other works by this author on:
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90 - 104: Metabolic Syndrome in Psychiatric Inpatients Treated for DepressionByJohn W. Goethe;John W. GoetheaBurlingame Center for Psychiatric Research and Education, Institute of Living, Hartford, Conn., andSearch for other works by this author on:Bonnie L. Szarek;Bonnie L. SzarekaBurlingame Center for Psychiatric Research and Education, Institute of Living, Hartford, Conn., andSearch for other works by this author on:Charles F. CaleyCharles F. CaleyaBurlingame Center for Psychiatric Research and Education, Institute of Living, Hartford, Conn., andbUniversity of Connecticut School of Pharmacy, Storrs, Conn., USASearch for other works by this author on:
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105 - 115: Hyperprolactinaemia Associated with Antipsychotic MedicationsByPeter Fitzgerald;Peter FitzgeraldDepartment of Psychiatry and Alimentary Pharmabiotic Centre, University College, Cork, IrelandSearch for other works by this author on:Timothy G. DinanTimothy G. DinanDepartment of Psychiatry and Alimentary Pharmabiotic Centre, University College, Cork, IrelandSearch for other works by this author on:
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116 - 128: Impact of Hyperprolactinaemia on the General Health of Patients with SchizophreniaByHiram J. Wildgust;Hiram J. WildgustaHiram Consulting, Ackworth, andSearch for other works by this author on:Dora KohenDora KohenbLancashire Postgraduate School of Medicine, Preston, UKSearch for other works by this author on: