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Chemical Immunology and Allergy
T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases
Edited by
S.Karger AG
Volume
94
Status:
Available
ISBN electronic:
978-3-8055-8629-0
ISBN print:
978-3-8055-8628-3
Book Series:
Chemical Immunology and Allergy
Publication date:
2008
Book Details
This book presents the state of the art in cellular and molecular mechanisms regulating the immune response in allergic inflammation. Special attention is given to the central role of regulatory T cells (Treg) in immune regulation and induction of peripheral tolerance, as well as to the relevance of Th17 cells in chronic inflammation. The importance of Treg and Th17 cells is demonstrated in bronchial asthma, atopic eczema, contact dermatitis and delayed-type hypersensitivity. Furthermore, T-cell-mediated regulatory mechanisms in helminthic infections and fungal allergy are discussed. Several chapters are devoted to the therapeutic consequences that these recently discovered T-cell functions may have. Their role as a potential target for specific immunotherapy is evaluated and novel approaches for peripheral tolerance induction and treatment of allergic and asthmatic diseases and inflammation are suggested. Stem cell transplantation as a future therapeutic intervention in regulatory T-cell disorders is also considered. Well edited and up to date, this volume is recommended reading for allergologists, immunologists, dermatologists and any scientist interested in the immunological events regulating allergic inflammation in general and allergic manifestations in different organs.
T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases
Edited by: K. Blaser
https://doi.org/10.1159/isbn.978-3-8055-8629-0
ISBN (print): 978-3-8055-8628-3
ISBN (electronic): 978-3-8055-8629-0
Publisher: S.Karger AG
Published: 2008
Download citation file:
Digital Version
Pay-Per-View Access
$233.00
Print Version
T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases
$233.00
Table of Contents
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1 - 7: Th17 and Treg Cells Innovate the Th1/Th2 Concept and Allergy ResearchByC. Schmidt-WeberC. Schmidt-WeberAllergy and Clinical Immunology, Imperial College London, London, UKSearch for other works by this author on:
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8 - 15: Regulatory T Cells and Antigen-Specific ToleranceByK. Kretschmer;K. KretschmerHarvard Medical School, Dana-Farber Cancer Institute, Boston, Mass., USASearch for other works by this author on:I. Apostolou;I. ApostolouHarvard Medical School, Dana-Farber Cancer Institute, Boston, Mass., USASearch for other works by this author on:P. Verginis;P. VerginisHarvard Medical School, Dana-Farber Cancer Institute, Boston, Mass., USASearch for other works by this author on:H. von BoehmerH. von BoehmerHarvard Medical School, Dana-Farber Cancer Institute, Boston, Mass., USASearch for other works by this author on:
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16 - 28: Molecular Mechanisms of Regulatory T-Cell DevelopmentByT. ChatilaT. ChatilaDivision of Immunology, Allergy and Rheumatology, Department of Pediatrics, The David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, Calif., USASearch for other works by this author on:
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29 - 39: Interaction of Regulatory T Cells with Antigen-Presenting Cells in Health and DiseaseByK. Mahnke;K. MahnkeDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, GermanySearch for other works by this author on:S. Ring;S. RingDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, GermanySearch for other works by this author on:T. Bedke;T. BedkeDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, GermanySearch for other works by this author on:S. Karakhanova;S. KarakhanovaDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, GermanySearch for other works by this author on:A. EnkA. EnkDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, GermanySearch for other works by this author on:
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40 - 47: Mucosal Regulatory T Cells in Airway HyperresponsivenessByD. Strickland;D. StricklandTelethon Institute for Child Health Research and Centre for Child Health Research, School of Paediatrics and Child Health, The University of Western Australia, Perth, WA, AustraliaSearch for other works by this author on:M. Wikstrom;M. WikstromTelethon Institute for Child Health Research and Centre for Child Health Research, School of Paediatrics and Child Health, The University of Western Australia, Perth, WA, AustraliaSearch for other works by this author on:D. Turner;D. TurnerTelethon Institute for Child Health Research and Centre for Child Health Research, School of Paediatrics and Child Health, The University of Western Australia, Perth, WA, AustraliaSearch for other works by this author on:P. HoltP. HoltTelethon Institute for Child Health Research and Centre for Child Health Research, School of Paediatrics and Child Health, The University of Western Australia, Perth, WA, AustraliaSearch for other works by this author on:
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48 - 57: Natural Killer Cells in Allergic InflammationByG. Erten;G. ErtenDepartment of Immunology, Institute of Experimental Medicine (DETAE), Istanbul University, Istanbul, TurkeySearch for other works by this author on:E. Aktas;E. AktasDepartment of Immunology, Institute of Experimental Medicine (DETAE), Istanbul University, Istanbul, TurkeySearch for other works by this author on:G. DenizG. DenizDepartment of Immunology, Institute of Experimental Medicine (DETAE), Istanbul University, Istanbul, TurkeySearch for other works by this author on:
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58 - 66: Mast Cells and Mast Cell-Derived Factors in the Regulation of Allergic SensitizationByC. Taube;C. TaubeaThird Medical Clinic and b Institute for Immunology, Johannes Gutenberg University, Mainz, GermanySearch for other works by this author on:M. StassenM. StassenaThird Medical Clinic and b Institute for Immunology, Johannes Gutenberg University, Mainz, GermanySearch for other works by this author on:
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67 - 82: Regulatory Effects of Histamine and Histamine Receptor Expression in Human Allergic Immune ResponsesByC. Akdis;C. AkdisaSwiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland, and bDepartment of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, PolandSearch for other works by this author on:M. Jutel;M. JutelaSwiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland, and bDepartment of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, PolandSearch for other works by this author on:M. AkdisM. AkdisaSwiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland, and bDepartment of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, PolandSearch for other works by this author on:
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83 - 92: T-Cell Regulation in Asthmatic DiseasesByS. FinottoS. FinottoLaboratory of Cellular and Molecular Lung Immunology, First Medical Clinic, Mainz, GermanySearch for other works by this author on:
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93 - 100: Immune Regulatory Mechanisms in Allergic Contact Dermatitis and Contact SensitizationByA. CavaniA. CavaniLaboratory of Immunology, Istituto Dermopatico dell’Immacolata, IDI-IRCCS, Rome, ItalySearch for other works by this author on:
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101 - 111: Regulatory Role of T Lymphocytes in Atopic DermatitisByT. Werfel;T. WerfelDepartment of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, GermanySearch for other works by this author on:M. WittmannM. WittmannDepartment of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, GermanySearch for other works by this author on:
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112 - 123: T-Cell Regulation in Helminth Parasite Infections: Implications for Inflammatory DiseasesByR. Maizels;R. MaizelsaInstitute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK, and b Leiden University Medical Center, Leiden, The NetherlandsSearch for other works by this author on:M. YazdanbakhshM. YazdanbakhshaInstitute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK, and b Leiden University Medical Center, Leiden, The NetherlandsSearch for other works by this author on:
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124 - 137: Immune Regulation and Tolerance to Fungi in the Lungs and SkinByL. Romani;L. RomaniDepartment of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:P. PuccettiP. PuccettiDepartment of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:
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138 - 149: Control of Delayed-Type Hypersensitivity by Ocular- Induced CD8+Regulatory T CellsByR. Cone;R. ConeDepartment of Immunology and the Connecticut Lions Vascular Vision Center, University of Connecticut Health Center, Farmington, Conn., USASearch for other works by this author on:S. Chattopadhyay;S. ChattopadhyayDepartment of Immunology and the Connecticut Lions Vascular Vision Center, University of Connecticut Health Center, Farmington, Conn., USASearch for other works by this author on:J. O’RourkeJ. O’RourkeDepartment of Immunology and the Connecticut Lions Vascular Vision Center, University of Connecticut Health Center, Farmington, Conn., USASearch for other works by this author on:
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150 - 157: Novel Therapeutic Strategies by Regulatory T Cells in AllergyByE. ElkordE. ElkordImmunology Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UKSearch for other works by this author on:
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158 - 177: T-Cell Regulatory Mechanisms in Specific ImmunotherapyByM. Jutel;M. JutelaDepartment of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, Poland, and b Swiss Institute of Allergy and Asthma Research (SIAF), Davos, SwitzerlandSearch for other works by this author on:C. AkdisC. AkdisaDepartment of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, Poland, and b Swiss Institute of Allergy and Asthma Research (SIAF), Davos, SwitzerlandSearch for other works by this author on:
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178 - 188: Control and Regulation of Peripheral Tolerance in Allergic Inflammatory Disease: Therapeutic ConsequencesByL. Li;L. LiDivision of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass., USASearch for other works by this author on:V. BoussiotisV. BoussiotisDivision of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass., USASearch for other works by this author on:
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189 - 200: Lung Dendritic Cells: Targets for Therapy in Allergic DiseaseByB. Lambrecht;B. LambrechtaDepartment of Respiratory Diseases, University Hospital Ghent, Ghent, Belgium, and bDepartment of Pulmonary Medicine, Erasmus MC, Rotterdam, The NetherlandsSearch for other works by this author on:H. HammadH. HammadaDepartment of Respiratory Diseases, University Hospital Ghent, Ghent, Belgium, and bDepartment of Pulmonary Medicine, Erasmus MC, Rotterdam, The NetherlandsSearch for other works by this author on:
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201 - 210: Antigen-Based Therapies Targeting the Expansion of Regulatory T Cells in Autoimmune and Allergic DiseaseByM. Leech;M. LeechaUniversity of Edinburgh, Institute of Immunology and Infection Research, School of Biological Sciences, and b Centre for Inflammation Research, Edinburgh, UKSearch for other works by this author on:S. AndertonS. AndertonaUniversity of Edinburgh, Institute of Immunology and Infection Research, School of Biological Sciences, and b Centre for Inflammation Research, Edinburgh, UKSearch for other works by this author on:
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211 - 219: Stem Cell Transplantation in Genetically Linked Regulatory T-Cell DisordersByS. ShenoyS. ShenoySt. Louis Children’s Hospital, St. Louis, Mo., USASearch for other works by this author on:
