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Biovalley Monographs
New Animal Models of Human Neurological Diseases
Edited by
S.Karger AG
Volume
2
Status:
Available
ISBN electronic:
978-3-8055-8406-7
ISBN print:
978-3-8055-8405-0
Book Series:
Biovalley Monographs
Subject Area:
Further Areas
,
Neurology and Neuroscience
,
Pathology and Cell Biology
,
Pharmacology
,
Psychiatry and Psychology
Publication date:
2008
Book Details
This publication describes in detail some animal models of outstanding importance for the study of human neurological diseases. An introductory article provides a definition of animal models, looks at the history and ethics of their use, and highlights the reasons why animal models are so useful in scientific research. The following chapters present some of the newer models which play a key role in the study of amyotrophic lateral sclerosis, multiple sclerosis, stroke and peripheral neuropathy. Their specific features are detailed in the method section of each paper, and their application to the study of human neurological diseases is discussed in a comprehensive manner, i.e. limits and challenges posed by these models are evaluated and potential improvements suggested. A valuable single source of information, this book is recommended reading for neuroscientists as well as for neurologists and neurosurgeons interested in preclinical research on human neurological diseases.
New Animal Models of Human Neurological Diseases
Edited by: P. Poindron, P. Piguet
https://doi.org/10.1159/isbn.978-3-8055-8406-7
ISBN (print): 978-3-8055-8405-0
ISBN (electronic): 978-3-8055-8406-7
Publisher: S.Karger AG
Published: 2008
Download citation file:
Digital Version
Pay-Per-View Access
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Print Version
New Animal Models of Human Neurological Diseases
$128.00
Table of Contents
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1 - 10: Theoretical Considerations on Animal ModelsByPhilippe Poindron;Philippe PoindronaLaboratoire de Pathologie des Communications entre Cellules Nerveuses et Musculaires, Faculté de Pharmacie, Université Louis-Pasteur, Strasbourg, France;Search for other works by this author on:Noëlle Callizot;Noëlle CallizotbNeuropharmacology, Phytopharm plc, Godmanchester, UK;Search for other works by this author on:Pascale PiguetPascale Piguetc Pharmazentrum, University of Basel, Basel, SwitzerlandSearch for other works by this author on:
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11 - 38: Mouse Models with Motor Neuron Defects as a Tool for Deciphering Amyotrophic Lateral Sclerosis: Applications, Limits and Future ChallengesByAndoni Echaniz-Laguna;Andoni Echaniz-LagunaaLaboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM U-692, Faculté de Médecine, Université Louis-Pasteur, etbDépartement de Neurologie, Hôpital Civil, Strasbourg, FranceSearch for other works by this author on:Bastien Fricker;Bastien FrickeraLaboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM U-692, Faculté de Médecine, Université Louis-Pasteur, etSearch for other works by this author on:Anissa Fergani;Anissa FerganiaLaboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM U-692, Faculté de Médecine, Université Louis-Pasteur, etSearch for other works by this author on:Jean-Philippe Loeffler;Jean-Philippe LoeffleraLaboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM U-692, Faculté de Médecine, Université Louis-Pasteur, etSearch for other works by this author on:Frédérique RenéFrédérique RenéaLaboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM U-692, Faculté de Médecine, Université Louis-Pasteur, etSearch for other works by this author on:
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39 - 51: A Chronic Relapsing Animal Model for Multiple Sclerosis: Myelin Oligodendrocyte Glycoprotein Induced Experimental Autoimmune Encephalomyelitis in Dark Agouti RatsByJochen Kinter;Jochen KinterNeurobiology, Department of Research, University Hospital Basel, Pharmacenter,Basel, SwitzerlandSearch for other works by this author on:Thomas Zeis;Thomas ZeisNeurobiology, Department of Research, University Hospital Basel, Pharmacenter,Basel, SwitzerlandSearch for other works by this author on:Nicole Schaeren-WiemersNicole Schaeren-WiemersNeurobiology, Department of Research, University Hospital Basel, Pharmacenter,Basel, SwitzerlandSearch for other works by this author on:
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52 - 65: Occlusion of the Middle Cerebral Artery in Rats: Refinement of an Animal Model for Human StrokeByErtugrul Cam;Ertugrul CamaDepartment of Anatomy, Institute of Veterinary Science, University of Zürich, andSearch for other works by this author on:Ertugrul Kilic;Ertugrul KilicbDepartment of Neurology, University Hospital Zürich, Zürich, Switzerland;Search for other works by this author on:Burak Yulug;Burak YulugcDepartment of Neurology, University of Uludag, Bursa, Turkey;Search for other works by this author on:Marie-Françoise RitzMarie-Françoise Ritzd Neurosurgery Laboratory, Department of Research, University Hospital Basel, Basel, SwitzerlandSearch for other works by this author on:
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66 - 80: Pyridoxine-Induced Peripheral Neuropathy: Animal Models and UsesByNoëlle Callizot;Noëlle CallizotbNeuropharmacology, Phytopharm plc, Godmanchester, UKSearch for other works by this author on:Philippe PoindronPhilippe PoindronaLaboratoire de Pathologie des Communications entre Cellules Nerveuses et Musculaires, Faculté de Pharmacie, Université Louis-Pasteur, Strasbourg, France;Search for other works by this author on:
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81 - 96: A Dopamine-Sensitive Inherited Motor Syndrome Linked to the frissonnant MutationByNoëlle Callizot;Noëlle CallizotaLaboratoire de Pathologie des Communications entre Cellules Nerveuses et Musculaires, Faculté de Pharmacie, Université Louis-Pasteur, Strasbourg, etSearch for other works by this author on:Jean-Louis Guenet;Jean-Louis GuenetbUnité de Génétique des Mammifères, Institut Pasteur, Paris, FranceSearch for other works by this author on:Philippe PoindronPhilippe PoindronaLaboratoire de Pathologie des Communications entre Cellules Nerveuses et Musculaires, Faculté de Pharmacie, Université Louis-Pasteur, Strasbourg, etSearch for other works by this author on:
