Intracranial Gliomas Part III - Innovative Treatment Modalities
At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.
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1 - 13: Photodynamic Therapy of Malignant GliomasBySadao Kaneko;Sadao KanekoDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:Shin Fujimoto;Shin FujimotoDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:Hideshi Yamaguchi;Hideshi YamaguchiDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:Toru Yamauchi;Toru YamauchiDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:Tetsuya Yoshimoto;Tetsuya YoshimotoDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:Koichi TokudaKoichi TokudaDepartment of Neurosurgery, Kashiwaba Neurosurgical Hospital, Sapporo, JapanSearch for other works by this author on:
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14 - 26: Laser-Induced Interstitial Thermotherapy of GliomasByIoannis Karampelas;Ioannis KarampelasDepartment of Neurological Surgery, Brain Tumor and Neuro-oncology Center, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, OH, USASearch for other works by this author on:Andrew E. SloanAndrew E. SloanDepartment of Neurological Surgery, Brain Tumor and Neuro-oncology Center, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, OH, USASearch for other works by this author on:
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27 - 38: Stereotactic Cryodestruction of GliomasByBoris V. Martynov;Boris V. MartynovDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:Andrey I. Kholyavin;Andrey I. KholyavinDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:Vladimir B. Nizkovolos;Vladimir B. NizkovolosDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:Valery E. Parfenov;Valery E. ParfenovDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:Gennady E. Trufanov;Gennady E. TrufanovDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:Dmitry V. SvistovDmitry V. SvistovDepartment of Neurosurgery, Military Medical Academy, Saint Petersburg, RussiaSearch for other works by this author on:
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39 - 47: High-Intensity Focused Ultrasound Ablation Therapy of GliomasByRyan D. Alkins;Ryan D. AlkinsDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, CanadaSearch for other works by this author on:Todd G. MainprizeTodd G. MainprizeDivision of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, CanadaSearch for other works by this author on:
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48 - 56: Boron Neutron Capture Therapy of Malignant GliomasByShin-Ichi Miyatake;Shin-Ichi MiyatakeaDepartment of Neurosurgery, Osaka Medical College, Osaka, andSearch for other works by this author on:Shinji Kawabata;Shinji KawabataaDepartment of Neurosurgery, Osaka Medical College, Osaka, andSearch for other works by this author on:Ryo Hiramatsu;Ryo HiramatsuaDepartment of Neurosurgery, Osaka Medical College, Osaka, andSearch for other works by this author on:Toshihiko Kuroiwa;Toshihiko KuroiwaaDepartment of Neurosurgery, Osaka Medical College, Osaka, andSearch for other works by this author on:Minoru Suzuki;Minoru SuzukibRadiation Oncology and Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kyoto, JapanSearch for other works by this author on:Koji OnoKoji OnobRadiation Oncology and Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kyoto, JapanSearch for other works by this author on:
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57 - 65: Proton and Carbon Ion Therapy of Intracranial GliomasByStephanie E. CombsStephanie E. CombsDepartment of Radiation Oncology, Technical University of Munich (TUM), Munich, GermanySearch for other works by this author on:
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66 - 78: Novel and Prospective Molecular Targets for Therapy of Intracranial GliomasByNicholas ButowskiNicholas ButowskiDivisions of Medical Neuro-Oncology, Translational Research in Neuro-Oncology, and Neurological Surgery, University of California San Francisco (UCSF), San Francisco, CA, USASearch for other works by this author on:
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79 - 89: Cytokine Therapy of GliomasByKenichiro Iwami;Kenichiro IwamiaDepartment of Neurosurgery, Aichi Medical University, Nagakute, andSearch for other works by this author on:Atsushi Natsume;Atsushi NatsumebDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya, JapanSearch for other works by this author on:Toshihiko WakabayashiToshihiko WakabayashibDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya, JapanSearch for other works by this author on:
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90 - 100: Cell-Based Immunotherapy of GliomasByRichard G. Everson;Richard G. EversonaDepartment of Neurosurgery,Search for other works by this author on:Joseph P. Antonios;Joseph P. AntoniosaDepartment of Neurosurgery,Search for other works by this author on:Linda M. LiauLinda M. LiauaDepartment of Neurosurgery,bBrain Research Institute, andcJonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, University of California Los Angeles (UCLA), Los Angeles, CA, USASearch for other works by this author on:
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101 - 111: Vaccine Therapy of High-Grade GliomasByEiichi Ishikawa;Eiichi IshikawaaDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, andSearch for other works by this author on:Yoshihiro Muragaki;Yoshihiro MuragakicFaculty of Advanced Techno-Surgery anddDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo, JapanSearch for other works by this author on:Tetsuya Yamamoto;Tetsuya YamamotoaDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, andSearch for other works by this author on:Akira MatsumuraAkira MatsumurabCell-Medicine Inc., Tsukuba, andSearch for other works by this author on:
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112 - 123: Gene Therapy and Virotherapy of GliomasByJulius W. Kim;Julius W. KimDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:Alan L. Chang;Alan L. ChangDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:J. Robert Kane;J. Robert KaneDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:Jacob S. Young;Jacob S. YoungDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:Jian Qiao;Jian QiaoDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:Maciej S. LesniakMaciej S. LesniakDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USASearch for other works by this author on:
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124 - 151: Stem Cell Therapy of GliomasByBrittany C. Parker Kerrigan;Brittany C. Parker KerriganDepartment of Neurosurgery and The Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:Anwar Hossain;Anwar HossainDepartment of Neurosurgery and The Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:Shinji Yamashita;Shinji YamashitaDepartment of Neurosurgery and The Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:Frederick F. LangFrederick F. LangDepartment of Neurosurgery and The Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:
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152 - 158: Convection-Enhanced Delivery for Management of Malignant GliomasBySujit S. PrabhuSujit S. PrabhuDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:
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159 - 171: Targeted Local Therapy for Management of Intracranial High-Grade GliomasByIddo Paldor;Iddo PaldorDepartment of Neurosurgery and Hunterian Neurosurgical Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USASearch for other works by this author on:Kaisorn L. Chaichana;Kaisorn L. ChaichanaDepartment of Neurosurgery and Hunterian Neurosurgical Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USASearch for other works by this author on:Henry Brem;Henry BremDepartment of Neurosurgery and Hunterian Neurosurgical Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USASearch for other works by this author on:Betty M. TylerBetty M. TylerDepartment of Neurosurgery and Hunterian Neurosurgical Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USASearch for other works by this author on:
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172 - 179: Extracellular Vesicles as a Platform for Glioma Therapeutic DevelopmentByDavid R. Santiago-Dieppa;David R. Santiago-DieppaaDepartment of Neurosurgery andbCenter for Theoretical and Applied Neuro-Oncology, Moores Cancer Center, University of California San Diego (UCSD), La Jolla, CA, USASearch for other works by this author on:David D. Gonda;David D. GondaaDepartment of Neurosurgery andbCenter for Theoretical and Applied Neuro-Oncology, Moores Cancer Center, University of California San Diego (UCSD), La Jolla, CA, USASearch for other works by this author on:Vincent J. Cheung;Vincent J. CheungaDepartment of Neurosurgery andbCenter for Theoretical and Applied Neuro-Oncology, Moores Cancer Center, University of California San Diego (UCSD), La Jolla, CA, USASearch for other works by this author on:Jeffery A. Steinberg;Jeffery A. SteinbergaDepartment of Neurosurgery andSearch for other works by this author on:Bob S. Carter;Bob S. CarteraDepartment of Neurosurgery andSearch for other works by this author on:Clark C. ChenClark C. ChenaDepartment of Neurosurgery andbCenter for Theoretical and Applied Neuro-Oncology, Moores Cancer Center, University of California San Diego (UCSD), La Jolla, CA, USASearch for other works by this author on:
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180 - 195: Alternating Electric Fields Therapy for Malignant Gliomas: From Bench Observation to Clinical RealityByEric T. Wong;Eric T. WongaBrain Tumor Center and Neuro-Oncology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, andbDepartment of Physics, University of Massachusetts in Lowell, Lowell, MA, USASearch for other works by this author on:Edwin Lok;Edwin LokaBrain Tumor Center and Neuro-Oncology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, andSearch for other works by this author on:Kenneth D. SwansonKenneth D. SwansonaBrain Tumor Center and Neuro-Oncology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, andSearch for other works by this author on:
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196 - 210: Perspectives of Nanotechnology in the Management of GliomasByJang W. Yoon;Jang W. YoonaDepartment of Neurosurgery, Mayo Clinic College of Medicine, Mayo Clinic Florida, Jacksonville, FL, andSearch for other works by this author on:Wen Jiang;Wen JiangbDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; andSearch for other works by this author on:James T. Rutka;James T. RutkacDivision of Neurosurgery, University of Toronto Hospital for Sick Children, Toronto, ON, CanadaSearch for other works by this author on:Yuhui Huang;Yuhui HuangaDepartment of Neurosurgery, Mayo Clinic College of Medicine, Mayo Clinic Florida, Jacksonville, FL, andSearch for other works by this author on:Betty Y.S. KimBetty Y.S. KimaDepartment of Neurosurgery, Mayo Clinic College of Medicine, Mayo Clinic Florida, Jacksonville, FL, andSearch for other works by this author on: