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Interdisciplinary Topics in Gerontology and Geriatrics
Mechanisms of Dietary Restriction in Aging and Disease
Edited by
S.Karger AG
Volume
35
Status:
Available
ISBN electronic:
978-3-318-01390-0
ISBN print:
978-3-8055-8170-7
Subject Area:
Endocrinology
,
Further Areas
,
Geriatrics and Gerontology
,
Neurology and Neuroscience
,
Nutrition and Dietetics
,
Oncology
Publication date:
2006
Book Details
Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the National Institute of Aging convened a program involving several leading gerontological laboratories. Results from many of these, as well as from other leading research institutions in the field, are presented in this book. The first three papers address general molecular mechanisms, derived in part from recent DNA microarray studies, that may mediate protective effects of dietary restriction. The subsequent articles examine specific model systems, including flies, nematodes and non-human primates, that have provided exciting new information about these mechanisms. Finally, mechanisms of dietary restriction mediating protective effects against cancer and neurological diseases are discussed. In addition to gerontologists and geriatricians, many other medical and nonmedical professionals in the field will find a great wealth of information on possible interventions that may ameliorate age-related diseases.
Mechanisms of Dietary Restriction in Aging and Disease
Edited by: K. Yen, C.V. Mobbs, P.R. Hof
https://doi.org/10.1159/isbn.978-3-318-01390-0
ISBN (print): 978-3-8055-8170-7
ISBN (electronic): 978-3-318-01390-0
Publisher: S.Karger AG
Published: 2006
Download citation file:
Digital Version
Pay-Per-View Access
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Print Version
Mechanisms of Dietary Restriction in Aging and Disease
$221.00
Table of Contents
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1 - 17: The Role of Hormesis in Life Extension by Dietary RestrictionByEdward J. MasoroEdward J. MasoroBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, Tex., USASearch for other works by this author on:
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18 - 38: Metabolic Reprogramming in Dietary RestrictionByRozalyn M. Anderson;Rozalyn M. AndersonDepartment of Medicine, University of Wisconsin, Madison, Wisc., USASearch for other works by this author on:Richard WeindruchRichard WeindruchDepartment of Medicine, University of Wisconsin, Madison, Wisc., USASearch for other works by this author on:
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39 - 68: Secrets of the lac Operon: Glucose Hysteresis as a Mechanism in Dietary Restriction, Aging and DiseaseByCharles V. Mobbs;Charles V. MobbsDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:Jason W. Mastaitis;Jason W. MastaitisDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:Minhua Zhang;Minhua ZhangDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:Fumiko Isoda;Fumiko IsodaDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:Hui Cheng;Hui ChengDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:Kelvin YenKelvin YenDepartments of Neuroscience and Geriatrics, Mount Sinai School of Medicine,New York, N.Y., USASearch for other works by this author on:
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69 - 82: Effects of Dietary Restriction on the Expression of Insulin-Signaling-Related Genes in Long-Lived Mutant MiceByAndrzej Bartke;Andrzej BartkeGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinois University School of Medicine, Springfield, Ill., USASearch for other works by this author on:Michal M. Masternak;Michal M. MasternakGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinois University School of Medicine, Springfield, Ill., USASearch for other works by this author on:Khalid A. Al-Regaiey;Khalid A. Al-RegaieyGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinois University School of Medicine, Springfield, Ill., USASearch for other works by this author on:Michael S. BonkowskiMichael S. BonkowskiGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinois University School of Medicine, Springfield, Ill., USASearch for other works by this author on:
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83 - 97: Anti-Inflammatory Mechanisms of Dietary Restriction in Slowing Aging ProcessesByT.E. Morgan;T.E. MorganLeonard Davis School of Gerontology and USC College,University of Southern California, Los Angeles, Calif., USASearch for other works by this author on:A.M. Wong;A.M. WongLeonard Davis School of Gerontology and USC College,University of Southern California, Los Angeles, Calif., USASearch for other works by this author on:C.E. FinchC.E. FinchLeonard Davis School of Gerontology and USC College,University of Southern California, Los Angeles, Calif., USASearch for other works by this author on:
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98 - 114: Dietary Restriction in the Nematode Caenorhabditis elegansByKoen Houthoofd;Koen HouthoofdaDepartment of Biology, Ghent University, Ghent, Belgium;b Department of Biology, UCL Centre for Research on Ageing, University College London, London, UK;Search for other works by this author on:David Gems;David Gemsb Department of Biology, UCL Centre for Research on Ageing, University College London, London, UK;Search for other works by this author on:Thomas E. Johnson;Thomas E. JohnsoncDepartment of Integrative Physiology, Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, Colo., USASearch for other works by this author on:Jacques R. VanfleterenJacques R. VanfleterenaDepartment of Biology, Ghent University, Ghent, Belgium;Search for other works by this author on:
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115 - 136: Diet Restriction in Drosophila melanogaster: Design and AnalysisByMarc TatarMarc TatarDivision of Biology and Medicine, Brown University, Providence, R.I., USASearch for other works by this author on:
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137 - 158: Dietary Restriction in Aging Nonhuman PrimatesByJulie A. Mattison;Julie A. MattisonIntramural Research Program, Laboratory of Experimental Gerontology,National Institute on Aging, Baltimore, Md., USASearch for other works by this author on:George S. Roth;George S. RothIntramural Research Program, Laboratory of Experimental Gerontology,National Institute on Aging, Baltimore, Md., USASearch for other works by this author on:Mark A. Lane;Mark A. LaneIntramural Research Program, Laboratory of Experimental Gerontology,National Institute on Aging, Baltimore, Md., USASearch for other works by this author on:Donald K. IngramDonald K. IngramIntramural Research Program, Laboratory of Experimental Gerontology,National Institute on Aging, Baltimore, Md., USASearch for other works by this author on:
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159 - 175: Caloric Intake and Alzheimer’s Disease: Experimental Approaches and Therapeutic ImplicationsByGiulio Maria Pasinetti;Giulio Maria PasinettiNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Zhong Zhao;Zhong ZhaoNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Weiping Qin;Weiping QinNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Lap Ho;Lap HoNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Yemul Shrishailam;Yemul ShrishailamNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Donal MacGrogan;Donal MacGroganNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Wendy Ressmann;Wendy RessmannNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Nelson Humala;Nelson HumalaNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Xunxian Liu;Xunxian LiuNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Carmen Romero;Carmen RomeroNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Breton Stetka;Breton StetkaNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Linghong Chen;Linghong ChenNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Hanna Ksiezak-Reding;Hanna Ksiezak-RedingNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:Jun WangJun WangNeuroinflammation Research Laboratories, Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y., and Bronx Veterans Affairs Medical Center,Mount Sinai School of Medicine, Bronx, N.Y., USASearch for other works by this author on:
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176 - 192: Can Short-Term Dietary Restriction and Fasting Have a Long-Term Anticarcinogenic Effect?BySimon KlebanovSimon KlebanovObesity Research Center, St. Luke’s Roosevelt Hospital Center, New York, N.Y., USASearch for other works by this author on:
