Immuno-OncologyAvailable to Purchase
Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolution in the history of cancer therapy. This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, transversal chapters that describe the commonalities of some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter has been authored by senior key opinion leaders in their respective fields to provide the most up-to-date view on cancer immuno-oncology. To reflect on the key translational aspect of immuno-oncology, all chapters are making explicit connections between basic science discoveries and the resulting translational therapeutic strategies. Immuno-Oncology will be an invaluable source of information for scientists interested in the translation of basic immunology into the clinical practice, as well as for clinician interested in deepening their knowledge of current and upcoming immune strategies in the fight against cancers.
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Table of Contents
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1 - 10: Immunotherapies in Early and Advanced Renal Cell CancerByBenjamin Kasenda;Benjamin KasendaMedical Oncology, Royal Marsden Hospital, London, UKSearch for other works by this author on:James Larkin;James LarkinMedical Oncology, Royal Marsden Hospital, London, UKSearch for other works by this author on:Martin GoreMartin GoreMedical Oncology, Royal Marsden Hospital, London, UKSearch for other works by this author on:
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11 - 21: Immunotherapy of Brain TumorsByValérie Dutoit;Valérie DutoitaLaboratory of Tumor Immunology,Search for other works by this author on:Denis Migliorini;Denis MigliorinibCenter of Oncology, Geneva University Hospitals, Geneva, SwitzerlandSearch for other works by this author on:Paul R. Walker;Paul R. WalkeraLaboratory of Tumor Immunology,Search for other works by this author on:Pierre-Yves DietrichPierre-Yves DietrichbCenter of Oncology, Geneva University Hospitals, Geneva, SwitzerlandSearch for other works by this author on:
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22 - 29: Immunotherapy of MelanomaByAlexandra Snyder;Alexandra SnyderaDepartment of Medicine,dWeill Cornell Medical College, New York, N.Y., USASearch for other works by this author on:Dmitriy Zamarin;Dmitriy ZamarinaDepartment of Medicine,bSwim Across America-Ludwig Collaborative Research Laboratory anddWeill Cornell Medical College, New York, N.Y., USASearch for other works by this author on:Jedd D. WolchokJedd D. WolchokaDepartment of Medicine,bSwim Across America-Ludwig Collaborative Research Laboratory andcImmunology Program, Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center, anddWeill Cornell Medical College, New York, N.Y., USASearch for other works by this author on:
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30 - 43: Immunotherapy of Breast CancerByCarmen Criscitiello;Carmen CriscitielloExperimental Therapeutics Division, European Institute of Oncology, Milan, ItalySearch for other works by this author on:Giuseppe CuriglianoGiuseppe CuriglianoExperimental Therapeutics Division, European Institute of Oncology, Milan, ItalySearch for other works by this author on:
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44 - 54: Current Developments in Actively Personalized Cancer Vaccination with a Focus on RNA as the Drug FormatByMustafa Diken;Mustafa DikenaTRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University, andbBioNTech RNA Pharmaceuticals GmbH, Mainz, GermanySearch for other works by this author on:Sebastian Kreiter;Sebastian KreiteraTRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University, andbBioNTech RNA Pharmaceuticals GmbH, Mainz, GermanySearch for other works by this author on:Björn Kloke;Björn KlokebBioNTech RNA Pharmaceuticals GmbH, Mainz, GermanySearch for other works by this author on:Ugur SahinUgur SahinaTRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University, andbBioNTech RNA Pharmaceuticals GmbH, Mainz, GermanySearch for other works by this author on:
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55 - 66: Immune Checkpoint InhibitorsByJohn B.A.G. Haanen;John B.A.G. HaanenaDivisions of Medical Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;Search for other works by this author on:Caroline RobertCaroline RobertbGustave Roussy, Service de Dermatologie et Université Paris-Sud, Villejuif-Paris, FranceSearch for other works by this author on:
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67 - 78: Radiotherapy and Immunotherapy: Improving Cancer Treatment through SynergyByKobe Reynders;Kobe ReyndersDepartment of Oncology, Experimental Radiation Oncology, KU Leuven - University of Leuven, Leuven, BelgiumSearch for other works by this author on:Dirk De RuysscherDirk De RuysscherDepartment of Oncology, Experimental Radiation Oncology, KU Leuven - University of Leuven, Leuven, BelgiumSearch for other works by this author on:
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79 - 94: Combinations TherapiesByNiels Reinmuth;Niels ReinmuthDepartment of Thoracic Oncology, LungenClinic Großhansdorf, Grosshansdorf and Airway Research Center North, German Center for Lung Research (DZL), Heidelberg, GermanySearch for other works by this author on:Martin ReckMartin ReckDepartment of Thoracic Oncology, LungenClinic Großhansdorf, Grosshansdorf and Airway Research Center North, German Center for Lung Research (DZL), Heidelberg, GermanySearch for other works by this author on:
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95 - 109: Promise of Immunotherapy in Lung CancerByAnil Shanker;Anil ShankeraDepartment of Biochemistry and Cancer Biology, Meharry Medical College School of Medicine, andbHost-Tumor Interactions Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tenn., andSearch for other works by this author on:Mikhail M. Dikov;Mikhail M. DikovcDivision of Medical Oncology, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, USASearch for other works by this author on:David P. CarboneDavid P. CarbonecDivision of Medical Oncology, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, USASearch for other works by this author on:
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110 - 135: T Cell EngineeringByMagdalena Pircher;Magdalena PircheraDepartment of Oncology, University Hospital Zurich, Zurich, Switzerland;Search for other works by this author on:Thomas Schirrmann;Thomas SchirrmannbInstitute of Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Braunschweig, GermanySearch for other works by this author on:Ulf PetrauschUlf PetrauschaDepartment of Oncology, University Hospital Zurich, Zurich, Switzerland;Search for other works by this author on: