Herpes Zoster: Recent Aspects of Diagnosis and ControlAvailable to Purchase
Herpes zoster (shingles) is a serious neurocutaneous disease caused by a reactivation of latent varicella-zoster virus (VZV). It has been underestimated in terms of its burden, particularly in the elderly population and in immunocompromised patients, who can develop severe complications such as postherpetic neuralgia, meningitis or optic nerve damage.
This book compiles state-of-the-art reviews on herpes zoster and VZV by leading clinicians and researchers in the field. They cover the molecular biology, latency and reactivation of the virus as well as the diagnosis, clinical manifestations, epidemiology and therapy of VZV infection. Infections in high-risk patients (immunocompromised hosts and bone marrow recipients) and pregnant women are considered in detail. Emphasis is also given to the direction of future research efforts which will be focused on the very early prevention of chronic zoster pain by combined antiviral and analgesic therapy, and on the control of herpes zoster by administering a VZV-specific vaccine.
Providing a valuable update on current strategies to diagnose, treat and prevent herpes zoster, this book is of special interest to clinical virologists, dermatologists, neurologists, gerontologists, pediatricians, ophthalmologists, otologists and general physicians.
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Table of Contents
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1 - 8: Molecular Biology of Varicella–Zoster VirusByMarkus Rahaus;Markus RahausInstitute of Microbiology and Virology, Private University of Witten-Herdecke, Witten, GermanySearch for other works by this author on:Nathalie Desloges;Nathalie DeslogesInstitute of Microbiology and Virology, Private University of Witten-Herdecke, Witten, GermanySearch for other works by this author on:Manfred H. WolffManfred H. WolffInstitute of Microbiology and Virology, Private University of Witten-Herdecke, Witten, GermanySearch for other works by this author on:
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9 - 12: Latency and Reactivation of VZVByOctavian Lungu;Octavian LunguaDepartments of Microbiology andSearch for other works by this author on:Anne A. GershonAnne A. Gershonb Pediatrics, Columbia University, College of Physicians and Surgeons, New York, N.Y., USASearch for other works by this author on:
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13 - 19: Laboratory Confirmation of Herpes ZosterByB. Ludwig;B. LudwigInstitute of Virology, University of Frankfurt, Frankfurt am Main, GermanySearch for other works by this author on:S. Buxbaum;S. BuxbaumInstitute of Virology, University of Frankfurt, Frankfurt am Main, GermanySearch for other works by this author on:H.W. DoerrH.W. DoerrInstitute of Virology, University of Frankfurt, Frankfurt am Main, GermanySearch for other works by this author on:
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20 - 36: Clinical Picture and Complications of Herpes Zoster: The View of the DermatologistByG. GrossG. GrossDepartment of Dermatology and Venereology, University of Rostock, Rostock, GermanySearch for other works by this author on:
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37 - 46: Ophthalmic Manifestations of Herpes Zoster InfectionByHermann GuembelHermann GuembelBundeswehrkrankenhaus Ulm, Academic Teaching Hospital of the University Clinics of Ulm, Ulm, GermanySearch for other works by this author on:
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47 - 57: (Herpes) Zoster OticusByH.W. PauH.W. PauDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty,University of Rostock, Rostock, GermanySearch for other works by this author on:
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58 - 68: Neuroanatomy of Pain and Neuropathology of Herpes Zoster and Postherpetic NeuralgiaByAndreas Wree;Andreas WreeaInstitute of Anatomy, Medical Faculty, University of Rostock, Rostock, Germany;Search for other works by this author on:Oliver Schmitt;Oliver SchmittaInstitute of Anatomy, Medical Faculty, University of Rostock, Rostock, Germany;Search for other works by this author on:Kamen G. UsunoffKamen G. UsunoffaInstitute of Anatomy, Medical Faculty, University of Rostock, Rostock, Germany;bDepartment of Anatomy and Histology, Preclinical University Center, Medical University of Sofia,c Institute of Physiology, Bulgarian Academy of Sciences, Sofia, BulgariaSearch for other works by this author on:
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69 - 80: Postherpetic Neuralgia and Other Neurologic ComplicationsByRalf BaronRalf BaronNeurological Clinic, Pain Research and Therapy, University Kiel, Kiel, GermanySearch for other works by this author on:
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81 - 92: Varicella–Zoster Virus Infections during PregnancyByAndreas Sauerbrei;Andreas SauerbreiInstitute of Virology and Antiviral Therapy, Friedrich-Schiller University,Jena, GermanySearch for other works by this author on:Peter WutzlerPeter WutzlerInstitute of Virology and Antiviral Therapy, Friedrich-Schiller University,Jena, GermanySearch for other works by this author on:
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93 - 106: Herpes Zoster in the Immunocompromised HostByHelmut SchöferHelmut SchöferDepartment of Dermatology, University Hospital, J.W. Goethe University,Frankfurt, GermanySearch for other works by this author on:
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107 - 116: Chickenpox and Zoster in Marrow Transplant RecipientsByI. Genvresse;I. GenvresseaDepartment of Haematology and Oncology, Charité University Hospital, Campus Virchow-Klinikum, Berlin;Search for other works by this author on:G. MaschmeyerG. MaschmeyerbDepartment of Haematology and Oncology, Klinikum Ernst von Bergmann, Potsdam, GermanySearch for other works by this author on:
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117 - 122: General Aspects of TherapyByG. GrossG. GrossDepartment of Dermatology and Venereology, University of Rostock,Rostock, GermanySearch for other works by this author on:
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123 - 130: Antiviral Therapy of Shingles in DermatologyByH. Martina Lilie;H. Martina LilieDermatology Department, Klinikum Krefeld, Krefeld, GermanySearch for other works by this author on:Sawko W. WassilewSawko W. WassilewDermatology Department, Klinikum Krefeld, Krefeld, GermanySearch for other works by this author on:
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131 - 142: Highly Potent and Selective Inhibition of Varicella–Zoster Virus Replication by Bicyclic Furo[2,3-d ]pyrimidine Nucleoside Analogues (BCNAs)ByErik De ClercqErik De ClercqRega Institute for Medical Research, Katholieke Universiteit Leuven,Leuven, BelgiumSearch for other works by this author on:
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143 - 153: Therapy of Zoster Pain, Postherpetic Neuralgia and Other Neurological ComplicationsByRalf BaronRalf BaronNeurological Clinic, Pain Research and Therapy, University Kiel,Kiel, GermanySearch for other works by this author on:
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154 - 163: Epidemiology of Herpes Zoster: What has Changed?ByRegina Allwinn;Regina AllwinnInstitute for Medical Virology, University Hospital of Frankfurt,Frankfurt am Main, GermanySearch for other works by this author on:Sigune Buxbaum;Sigune BuxbaumInstitute for Medical Virology, University Hospital of Frankfurt,Frankfurt am Main, GermanySearch for other works by this author on:Hans Wilhelm DoerrHans Wilhelm DoerrInstitute for Medical Virology, University Hospital of Frankfurt,Frankfurt am Main, GermanySearch for other works by this author on:
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164 - 169: Live Attenuated Varicella VaccineByAnne A. GershonAnne A. GershonDepartment of Pediatrics, Columbia University College of Physicians and Surgeons,New York, N.Y., USASearch for other works by this author on:
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170 - 188: Appendix: Herpes Zoster Guideline1 of the German Dermatology Society (DDG)2ByG. Gross;G. GrossaUniversitätsklinik and Poliklinik für Dermatologie und Venerologie, Rostock;Search for other works by this author on:H. Schöfer;H. SchöferbHautklinik, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt a. M.;Search for other works by this author on:S. Wassilew;S. WassilewcStädtische Hautklinik, Krefeld, Krefeld;Search for other works by this author on:K. Friese;K. FriesedUniversitäts-Frauenklinik und Poliklinik;Search for other works by this author on:A. Timm;A. TimmeUniversitäts-Augenklinik, Universität Rostock, andSearch for other works by this author on:R. Guthoff;R. GuthoffcStädtische Hautklinik, Krefeld, Krefeld;Search for other works by this author on:H.W. Pau;H.W. Pauf Universitätsklinik für Hals-Nasen-Ohren-Krankheiten, Universität Rostock, Rostock;Search for other works by this author on:J.P. Malin;J.P. Maling Neurologische Klinik,Universität Bochum, Bochum;Search for other works by this author on:P. Wutzler;P. WutzlerhInstitut für Antivirale Chemotherapie, Universität Jena, Jena;Search for other works by this author on:H.W. DoerrH.W. DoerriInstitut für Medizinische Virologie, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt a. M., Germany.Search for other works by this author on: