Immunology of PregnancyAvailable to Purchase
Pregnancy is a unique symbiotic union between mother and fetus which contradicts many of the general rules of immunology. The maternal immune system reacts towards the foreign tissue, but instead of triggering rejection, it tolerates, supports and regulates its development. The immunological mechanisms allowing the fetus to grow and survive are complex and may be affected by internal and external factors which may result in pregnancy disorders including infertility, abortions and preeclamptic disease. In this book leading scientists present the latest findings on the physiological mechanisms required for successful pregnancies, and the pathologies that may be caused by a disturbance of these mechanisms. The regulation of maternal NK cells, T cells and dendritic cells through hormones, cytokines, the complement system and HLA as well as other cell surface molecules is described in detail. The knowledge gained from the immunoregulation of pregnancy is also important in other fields of immunology and may lead to new therapeutic concepts in posttransplantation or allergy therapies, or in the fight against cancer.
This volume provides fascinating insights for those readers who are not yet familiar with the immunology of reproduction while it also serves to update specialists on the most recent findings in the field.
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Table of Contents
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1 - 2: The ‘Hatching’ of Reproductive ImmunologyByRadslav KinskýRadslav KinskýZdar nad Sazavou, Czech RepublicSearch for other works by this author on:
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3 - 9: T Cells in PregnancyByMarie-Pierre PiccinniMarie-Pierre PiccinniDepartment of Internal Medicine, Immunoallergology Unit,University of Florence, Florence, ItalySearch for other works by this author on:
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10 - 25: Physiological Role of IL-15 and IL-18 at the Maternal-Fetal InterfaceByGordana Laskarin;Gordana LaskarinaDepartment of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia;Search for other works by this author on:Natasa Strbo;Natasa StrboaDepartment of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia;Search for other works by this author on:Tatjana Bogovic Crncic;Tatjana Bogovic CrncicaDepartment of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia;Search for other works by this author on:Koraljka Juretic;Koraljka JureticaDepartment of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia;Search for other works by this author on:Nathalie Ledee Bataille;Nathalie Ledee BataillebU131 INSERM, Hospital Antoine Béclère, Clamart, FranceSearch for other works by this author on:Gerard Chaouat;Gerard ChaouatbU131 INSERM, Hospital Antoine Béclère, Clamart, FranceSearch for other works by this author on:Daniel RukavinaDaniel RukavinaaDepartment of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia;Search for other works by this author on:
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26 - 35: The Possible Role of the JAK/STAT Pathway in Lymphocytes at the Fetomaternal InterfaceByTobias G. Poehlmann;Tobias G. PoehlmannDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Susann Busch;Susann BuschDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Bianka Mussil;Bianka MussilDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Harald Winzer;Harald WinzerDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Judith Weinert;Judith WeinertDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Imke Mebes;Imke MebesDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Andreas Schaumann;Andreas SchaumannDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Justine S. Fitzgerald;Justine S. FitzgeraldDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Udo R. MarkertUdo R. MarkertDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:
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36 - 48: Tolerance Signaling MoleculesByDavid A. ClarkDavid A. ClarkMcMaster University, Hamilton, CanadaSearch for other works by this author on:
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49 - 61: Immunology of PreeclampsiaByLeif Matthiesen;Leif MatthiesenaDepartment of Molecular and Clinical Medicine, Division of Obstetrics and Gynaecology andSearch for other works by this author on:Göran Berg;Göran BergaDepartment of Molecular and Clinical Medicine, Division of Obstetrics and Gynaecology andSearch for other works by this author on:Jan Ernerudh;Jan Ernerudhb Department of Molecular and Clinical Medicine, Division of Clinical Immunology, University Hospital, Linkoping, Sweden;Search for other works by this author on:Christina Ekerfelt;Christina Ekerfeltb Department of Molecular and Clinical Medicine, Division of Clinical Immunology, University Hospital, Linkoping, Sweden;Search for other works by this author on:Yvonne Jonsson;Yvonne Jonssonb Department of Molecular and Clinical Medicine, Division of Clinical Immunology, University Hospital, Linkoping, Sweden;Search for other works by this author on:Surendra SharmaSurendra SharmacDepartment of Pediatrics and Pathology, Women and Infants Hospital of Rhode Island, Brown University, Providence, R.I., USASearch for other works by this author on:
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62 - 71: TNF-α-Mediated Stress-Induced Early Pregnancy Loss:A Possible Role of Leukemia Inhibitory FactorByA. Torchinsky;A. TorchinskyaDepartment of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;Search for other works by this author on:U.R. Markert;U.R. Markertb Placenta-Labor, Abteilung für Geburtshilfe,Friedrich-Shiller-Universität, Jena, GermanySearch for other works by this author on:V. ToderV. ToderaDepartment of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel;Search for other works by this author on:
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72 - 83: HLA Class I/NK Cell Receptor Interaction in Early Human Decidua basalis: Possible Functional ConsequencesByMagali Rabot;Magali RabotaINSERM U563, Hôpital Purpan andSearch for other works by this author on:Julie Tabiasco;Julie TabiascoaINSERM U563, Hôpital Purpan andSearch for other works by this author on:Beata Polgar;Beata PolgaraINSERM U563, Hôpital Purpan andSearch for other works by this author on:Maryse Aguerre-Girr;Maryse Aguerre-GirraINSERM U563, Hôpital Purpan andSearch for other works by this author on:Alain Berrebi;Alain BerrebiaINSERM U563, Hôpital Purpan andb Department of Obstetrics and Gynecology, Hopital Paule de Viguier, Toulouse, andSearch for other works by this author on:Armand Bensussan;Armand BensussancFaculté de Médecine de Créteil, INSERM 659, Créteil, France;Search for other works by this author on:Natasa Strbo;Natasa Strbod Department of Physiology and Immunology, Medical Faculty,University of Rijeka, Rijeka, CroatiaSearch for other works by this author on:Daniel Rukavina;Daniel Rukavinad Department of Physiology and Immunology, Medical Faculty,University of Rijeka, Rijeka, CroatiaSearch for other works by this author on:Philippe Le BouteillerPhilippe Le BouteilleraINSERM U563, Hôpital Purpan andSearch for other works by this author on:
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84 - 95: The Significance of the Women’s Repertoire of Natural Killer Cell Receptors in the Maintenance of PregnancyByM. Varla-LeftheriotiM. Varla-LeftheriotiImmunobiology Department, RSA Clinic,‘Helena Venizelou’ Maternity Hospital, Athens, GreeceSearch for other works by this author on:
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96 - 104: Antigen-Presenting Cells in the DeciduaByUlrike KämmererUlrike KämmererDepartment of Obstetrics and Gynecology,University of Würzburg, Würzburg, GermanySearch for other works by this author on:
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105 - 117: Regulation of Leukocyte Recruitment to the Murine Maternal/Fetal InterfaceByUta Fernekorn;Uta FernekornInstitute of Immunology and Transfusion Medicine,University of Lübeck, Lübeck, GermanySearch for other works by this author on:Andrea KruseAndrea KruseInstitute of Immunology and Transfusion Medicine,University of Lübeck, Lübeck, GermanySearch for other works by this author on:
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118 - 125: Progesterone-Dependent ImmunomodulationByJ. Szekeres-Bartho;J. Szekeres-BarthoDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:B. Polgar;B. PolgarDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:N. Kozma;N. KozmaDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:E. Miko;E. MikoDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:G. Par;G. ParDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:L. Szereday;L. SzeredayDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:A. Barakonyi;A. BarakonyiDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:T. Palkovics;T. PalkovicsDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:O. Papp;O. PappDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:P. VargaP. VargaDepartment of Medical Microbiology and Immunology, Pecs University, Medical School, Reproductive and Tumor Immunology Research Group of the Hungarian Academy of Sciences, Pecs, HungarySearch for other works by this author on:
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126 - 134: Regeneration and Tolerance Factor: A Vacuolar ATPase with ConsequencesByRita F. Levine;Rita F. LevineClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, Ill., USASearch for other works by this author on:Richards Derks;Richards DerksClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, Ill., USASearch for other works by this author on:Kenneth BeamanKenneth BeamanClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, Ill., USASearch for other works by this author on:
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135 - 148: Nerve Growth Factor in Reproductive Biology: Link between the Immune, Endocrine and Nervous System?ByMareike Tometten;Mareike TomettenCharité, University Medicine Berlin, Berlin, GermanySearch for other works by this author on:Sandra Blois;Sandra BloisCharité, University Medicine Berlin, Berlin, GermanySearch for other works by this author on:Petra C. ArckPetra C. ArckCharité, University Medicine Berlin, Berlin, GermanySearch for other works by this author on:
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149 - 157: The Complement System at the Fetomaternal InterfaceByRoberta Bulla;Roberta BullaaDepartment of Physiology and Pathology,Search for other works by this author on:Fleur Bossi;Fleur BossiaDepartment of Physiology and Pathology,Search for other works by this author on:Fabio Fischetti;Fabio Fischettib Department of Medicine and Neurology andSearch for other works by this author on:Francesco De Seta;Francesco De SetacDepartment of Reproductive and Developmental Sciences, IRCCS Burlo Garofolo, University of Trieste, Trieste, ItalySearch for other works by this author on:Francesco TedescoFrancesco TedescoaDepartment of Physiology and Pathology,Search for other works by this author on:
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158 - 168: Asymmetric Antibodies:A Protective Arm in PregnancyByG. Gutierrez;G. GutierrezIDEHU-Institute of Humoral Immunity Studies (CONICET-UBA),School of Pharmacy and Biochemistry, University of Buenos Aires,Buenos Aires, ArgentinaSearch for other works by this author on:T. Gentile;T. GentileIDEHU-Institute of Humoral Immunity Studies (CONICET-UBA),School of Pharmacy and Biochemistry, University of Buenos Aires,Buenos Aires, ArgentinaSearch for other works by this author on:S. Miranda;S. MirandaIDEHU-Institute of Humoral Immunity Studies (CONICET-UBA),School of Pharmacy and Biochemistry, University of Buenos Aires,Buenos Aires, ArgentinaSearch for other works by this author on:R.A. MargniR.A. MargniIDEHU-Institute of Humoral Immunity Studies (CONICET-UBA),School of Pharmacy and Biochemistry, University of Buenos Aires,Buenos Aires, ArgentinaSearch for other works by this author on:
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169 - 179: Lessons from Reproductive Immunology for Other Fields of Immunology and Clinical ApproachesByUdo R. Markert;Udo R. MarkertDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Justine S. Fitzgerald;Justine S. FitzgeraldDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Lydia Seyfarth;Lydia SeyfarthDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Joana Heinzelmann;Joana HeinzelmannDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Frauke Varosi;Frauke VarosiDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Sandra Voigt;Sandra VoigtDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Ekkehard Schleussner;Ekkehard SchleussnerDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on:Hans-Joachim SeewaldHans-Joachim SeewaldDepartment of Obstetrics, Friedrich Schiller University, Jena, GermanySearch for other works by this author on: