Cardiovascular Disorders in Hemodialysis: 14th International Course on Hemodialysis, Vicenza, May 2005
Hemodialysis therapy has become a well-established form of renal replacement, and due to continuous improvements in technology, a series of new biomaterials and techniques for the clinical routine have been developed. Nevertheless, cardiovascular disorders in hemodialysis and uremia represent one of the most important aspects of modern nephrological care. This publication is therefore dedicated to cardiovascular risk factors, the role of the endothelium, problems related to mineral disorders and finally to the possible impact of new technologies on the final outcome in hemodialysis. Being a state-of-the-art appraisal of today’s technology and current issues in hemodialysis with special regard to cardiovascular disorders and risk factors, this book is a synthesis between an educational effort aimed at the newer generations of physicians and nurses in the field of hemodialysis and a state-of-the-art description of the most advanced technologies in this field. At the same time, the lessons learned from large international trials, either already completed or to be completed in the years to come, are presented.
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Table of Contents
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1 - 9: Hemodialysis – From Early Days to TomorrowByEberhard Ritz;Eberhard RitzDepartment Internal Medicine, Ruperto-Carola-University,Heidelberg, GermanySearch for other works by this author on:Ralf Dikow;Ralf DikowDepartment Internal Medicine, Ruperto-Carola-University,Heidelberg, GermanySearch for other works by this author on:Vedat Schwenger;Vedat SchwengerDepartment Internal Medicine, Ruperto-Carola-University,Heidelberg, GermanySearch for other works by this author on:Marie-Luise GrossMarie-Luise GrossDepartment Internal Medicine, Ruperto-Carola-University,Heidelberg, GermanySearch for other works by this author on:
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10 - 17: Mechanisms of Solute Transport in Extracorporeal TherapiesByClaudio Ronco;Claudio RoncoaDepartment of Nephrology, St. Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Nathan W. LevinNathan W. LevinbRenal Research Institute, Beth Israel Medical Center, New York, N.Y., USASearch for other works by this author on:
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18 - 26: Machines for HemodialysisByHans-Dietrich PolascheggHans-Dietrich PolascheggMedical Devises Consultant Köstenberg, AustriaSearch for other works by this author on:
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27 - 34: Mathematical Model to Characterize Internal FiltrationByGianfranco Beniamino Fiore;Gianfranco Beniamino FioreaDepartment of Bioengineering, Politecnico di Milano, Milano, andSearch for other works by this author on:Claudio RoncoClaudio RoncobDepartment of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:
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35 - 41: Extracorporeal Sensing TechniquesByDaniel SchneditzDaniel SchneditzInstitute of Physiology, Medical University Graz, Graz, AustriaSearch for other works by this author on:
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42 - 50: Water Treatment for Hemodialysis: A 2005 UpdateByGianni Cappelli;Gianni CappelliNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:Federica Ravera;Federica RaveraNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:Marco Ricardi;Marco RicardiNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:Marco Ballestri;Marco BallestriNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:Salvatore Perrone;Salvatore PerroneNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:Alberto AlbertazziAlberto AlbertazziNephrology Dialysis and Renal Transplantation Unit,University Hospital of Modena, Modena, ItalySearch for other works by this author on:
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51 - 57: Online Convective Therapies: Results from a Hemofiltration TrialByA. Santoro;A. SantoroaU.O. Nefrologia e Dialisi Malpighi, Policlinico S.Orsola-Malpighi, Bologna,Search for other works by this author on:E. Mancini;E. ManciniaU.O. Nefrologia e Dialisi Malpighi, Policlinico S.Orsola-Malpighi, Bologna,Search for other works by this author on:A. Specchio;A. Specchioc Ospedale T. Russo, Cerignola (Fg),Search for other works by this author on:M.A. Nicolini;M.A. Nicolinif Ospedale S.Andrea, La Spezia,Search for other works by this author on:A. Fracasso;A. FracassohOspedale Umberto I, Mestre (Ve),Search for other works by this author on:M. Virgilio;M. Virgilioi Ospedale Civile, Molfetta (Ba),Search for other works by this author on:G. Campolo;G. CampololOspedale Misericordia e Dolce, Prato (Fi),Search for other works by this author on:F. De Tomaso;F. De Tomasom Ospedale S. Maria degli Angeli, Putignano (Ba),Search for other works by this author on:A. Montanari;A. MontanarinOspedale S.Maria delle Croci, Ravenna,Search for other works by this author on:A. Gattiani;A. Gattianio Ospedale degli Infermi, Rimini,Search for other works by this author on:F. Aucella;F. Aucellap Casa Sollievo della Sofferenza, S. Giovanni, Rotondo (Fg),Search for other works by this author on:R. Estivi;R. Estivir Ospedale S. Salvatore, Tolentino (Mc), andSearch for other works by this author on:S. CostantiniS. Costantinis Ospedale Belcolle, Viterbo, ItalySearch for other works by this author on:
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58 - 68: Selected Lessons Learned from the Dialysis Outcomes and Practice Patterns Study (DOPPS)ByRonald L. Pisoni;Ronald L. PisoniaUniversity Renal Research and Education Association, Ann Arbor, Mich., USA;Search for other works by this author on:Roger N. GreenwoodRoger N. GreenwoodbLister Hospital, Stevenage, UKSearch for other works by this author on:
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69 - 82: What Did We Learn from the HEMO Study? Implications of Secondary AnalysesByTom GreeneTom GreeneDepartment of Biostatistics and Epidemiology, Cleveland Clinic Foundation, Cleveland, Ohio, USASearch for other works by this author on:
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83 - 89: What Are We Expecting to Learn from the MPO Study?ByFrancesco Locatelli;Francesco LocatelliDepartment of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, ItalySearch for other works by this author on:Pietro Pozzoni;Pietro PozzoniDepartment of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, ItalySearch for other works by this author on:Salvatore Di FilippoSalvatore Di FilippoDepartment of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, ItalySearch for other works by this author on:
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90 - 99: A New Initiative in Nephrology: ‘Kidney Disease: Improving Global Outcomes’ByNorbert Lameire;Norbert LameireaUniversity Hospital of Ghent, Ghent, Belgium;Search for other works by this author on:Garabed Eknoyan;Garabed Eknoyanb Baylor College of Medicine, Houston, Texas;Search for other works by this author on:Rashad Barsoum;Rashad Barsoumc Cairo Kidney Center, Cairo University, Cairo, Egypt;Search for other works by this author on:Kai-Uwe Eckardt;Kai-Uwe EckardtdUniversity of Erlangen-Nuremberg, Erlangen, Germany;Search for other works by this author on:Adeera Levin;Adeera Levine University of British Columbia, Vancouver, British Columbia, Canada;Search for other works by this author on:Nathan Levin;Nathan Levinf Renal Research Institute, New York, New York;Search for other works by this author on:Francesco Locatelli;Francesco Locatellig A. Manzoni Hospital, Lecco, Italy;Search for other works by this author on:Alison MacLeod;Alison MacLeodh University of Aberdeen Medical School, Aberdeen, United Kingdom;Search for other works by this author on:Raymond Vanholder;Raymond VanholderaUniversity Hospital of Ghent, Ghent, Belgium;Search for other works by this author on:Rowan Walker;Rowan Walkeri Royal Melbourne Hospital,Melbourne, Australia; andSearch for other works by this author on:Haiyan WangHaiyan Wangk Peking University, The First Hospital, Beijing,Peoples Republic of ChinaSearch for other works by this author on:
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100 - 106: Is There a Magic in Long Nocturnal Dialysis?ByBernard CharraBernard CharraCentre de Rein Artificiel de Tassin, Tassin, FranceSearch for other works by this author on:
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107 - 114: Mid-Dilution: The Perfect Balance between Convection and DiffusionByA. Santoro;A. SantoroaU.O. Nefrologia e Dialisi Malpighi, Policlinico S. Orsola-Malpighi, Bologna,Search for other works by this author on:R. Gaggi;R. GaggiaU.O. Nefrologia e Dialisi Malpighi, Policlinico S. Orsola-Malpighi, Bologna,Search for other works by this author on:E. Ferramosca;E. FerramoscaaU.O. Nefrologia e Dialisi Malpighi, Policlinico S. Orsola-Malpighi, Bologna,Search for other works by this author on:M.L. WrattenM.L. Wrattend Bellco Spa, Mirandola, ItalySearch for other works by this author on:
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115 - 120: Sequential Hemofiltration- Hemodiafiltration Technique: All in One?ByM. Amato;M. AmatoaNephrology Department, Prato Hospital, Prato, andSearch for other works by this author on:A. Brendolan;A. Brendolanb Department of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:G. Campolo;G. CampoloaNephrology Department, Prato Hospital, Prato, andSearch for other works by this author on:D. Petras;D. Petrasb Department of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:M. Bonello;M. Bonellob Department of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:C. Crepaldi;C. Crepaldib Department of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:C. RoncoC. Roncob Department of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:
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121 - 130: Should Nephrologists Be in Charge?ByKlaus KonnerKlaus KonnerDepartment of Internal Medicine I, Cologne General Hospital University of Cologne, Cologne, GermanySearch for other works by this author on:
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131 - 137: Challenges in Interventional NephrologyByMiguel C. RiellaMiguel C. RiellaRenal Division, Catholic University of Parana, Brazil,and Chairman of the Interventional Nephrology Committee of the International Society of NephrologySearch for other works by this author on:
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138 - 149: Vascular Access Education, Planning and Percutaneous Interventions by NephrologistsByArif Asif;Arif AsifDepartment of Medicine Division of Nephrology,University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:Donna Merrill;Donna MerrillDepartment of Medicine Division of Nephrology,University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:Phillip PennellPhillip PennellDepartment of Medicine Division of Nephrology,University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:
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150 - 161: Whole Body – Single Frequency BioimpedanceByAntonio PiccoliAntonio PiccoliDepartment of Medical and Surgical Sciences,Nephrology Clinic, University of Padova, Padova, ItalySearch for other works by this author on:
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162 - 167: Use of Segmental Multifrequency Bioimpedance Spectroscopy in HemodialysisByNathan W. Levin;Nathan W. LevinaRenal Research Institute, New York, N.Y., USA;Search for other works by this author on:Fansan Zhu;Fansan ZhuaRenal Research Institute, New York, N.Y., USA;Search for other works by this author on:Eric Seibert;Eric SeibertaRenal Research Institute, New York, N.Y., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncobDepartment of Nephrology, St. Bartolo Hospital, Vicenza, ItalySearch for other works by this author on:Martin K. KuhlmannMartin K. KuhlmannaRenal Research Institute, New York, N.Y., USA;Search for other works by this author on:
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168 - 174: Cardiovascular Risk in Patients with End-Stage Renal Disease: A Potential Role for Advanced Glycation End ProductsByYingjie Wang;Yingjie WangFaculty of Medical Sciences, Medical School, University of Newcastle-upon-Tyne, UKSearch for other works by this author on:Sally M. Marshall;Sally M. MarshallFaculty of Medical Sciences, Medical School, University of Newcastle-upon-Tyne, UKSearch for other works by this author on:Michael G. Thompson;Michael G. ThompsonFaculty of Medical Sciences, Medical School, University of Newcastle-upon-Tyne, UKSearch for other works by this author on:Nicholas A. HoenichNicholas A. HoenichFaculty of Medical Sciences, Medical School, University of Newcastle-upon-Tyne, UKSearch for other works by this author on:
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175 - 184: Improving Removal of Protein-Bound Retention SolutesByBert Bammens;Bert BammensDepartment of Medicine, Division of Nephrology,University Hospital Gasthuisberg, Leuven, BelgiumSearch for other works by this author on:Pieter EvenepoelPieter EvenepoelDepartment of Medicine, Division of Nephrology,University Hospital Gasthuisberg, Leuven, BelgiumSearch for other works by this author on:
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185 - 199: Inflammation in End-Stage Renal Disease – A Fire that Burns withinByPeter StenvinkelPeter StenvinkelDivision of Renal Medicine, Department of Clinical Science,Karolinska University Hospital, Karolinska Institutet, Stockholm, SwedenSearch for other works by this author on:
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200 - 207: Interaction between Nutrition and Inflammation in Hemodialysis PatientsByMartin K. Kuhlmann;Martin K. KuhlmannRenal Research Institute, New York, N.Y., USASearch for other works by this author on:Nathan W. LevinNathan W. LevinRenal Research Institute, New York, N.Y., USASearch for other works by this author on:
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208 - 218: Monocytes from Dialysis Patients Exhibit Characteristics of Senescent Cells: Does It Really Mean Inflammation?ByJulia Carracedo;Julia CarracedoUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Rafael Ramirez;Rafael RamirezUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Sagrario Soriano;Sagrario SorianoUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Maria Antonia Alvarez de Lara;Maria Antonia Alvarez de LaraUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Mariano Rodriguez;Mariano RodriguezUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Alejandro Martin-Malo;Alejandro Martin-MaloUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:Pedro AljamaPedro AljamaUnidad de Investigación, Servicio de Nefrología. Hospital Universitario Reina Sofía,Córdoba, SpainSearch for other works by this author on:
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219 - 229: Modifiable Risk Factors for Cardiovascular Disease in CKD PatientsByEric Seibert;Eric SeibertRenal Research Institute, New York, N.Y., USASearch for other works by this author on:Martin K. Kuhlmann;Martin K. KuhlmannRenal Research Institute, New York, N.Y., USASearch for other works by this author on:Nathan W. LevinNathan W. LevinRenal Research Institute, New York, N.Y., USASearch for other works by this author on:
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230 - 239: The Cardiovascular Burden of the Dialysis Patient: The Impact of Dialysis TechnologyBySudhir K Bowry;Sudhir K BowryaFresenius Medical Care, Scientific Affairs, Bad Homburg, Germany;Search for other works by this author on:Ute Kuchinke-Kiehn;Ute Kuchinke-KiehnaFresenius Medical Care, Scientific Affairs, Bad Homburg, Germany;Search for other works by this author on:Claudio RoncoClaudio RoncobDepartment of Nephrology, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:
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240 - 260: Oxidative Stress and Reactive Oxygen SpeciesByFrancesco Galli;Francesco GalliDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:Marta Piroddi;Marta PiroddiDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:Claudia Annetti;Claudia AnnettiDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:Cristina Aisa;Cristina AisaDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:Emanuela Floridi;Emanuela FloridiDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:Ardesio FloridiArdesio FloridiDepartment of Internal Medicine, Section of Applied Biochemistry and Nutritional Sciences, University of Perugia, Perugia, ItalySearch for other works by this author on:
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261 - 271: Calcium, Phosphorus and Vitamin D Disorders in UremiaByEduardo Slatopolsky;Eduardo SlatopolskyWashington University School of Medicine, Department of Medicine, Renal Division, St. Louis, Mo., USASearch for other works by this author on:Alex Brown;Alex BrownWashington University School of Medicine, Department of Medicine, Renal Division, St. Louis, Mo., USASearch for other works by this author on:Adriana DussoAdriana DussoWashington University School of Medicine, Department of Medicine, Renal Division, St. Louis, Mo., USASearch for other works by this author on:
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272 - 278: Cardiovascular Calcification in End Stage Renal DiseaseByPaolo RaggiPaolo RaggiNew Orleans, LA., USASearch for other works by this author on:
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279 - 286: The Mechanism of Calcium Deposition in Soft TissuesByDiego Brancaccio;Diego BrancaccioRenal Unit, San Paolo Hospital, Milan, ItalySearch for other works by this author on:Mario CozzolinoMario CozzolinoRenal Unit, San Paolo Hospital, Milan, ItalySearch for other works by this author on:
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287 - 294: Biosimilars, Generic Versions of the First Generation of Therapeutic Proteins: Do They Exist?ByDaan Crommelin;Daan CrommelinaFaculty of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands;Search for other works by this author on:Theresa Bermejo;Theresa BermejobServicio de Farmacia, Hospital Ramón y Cajal, Madrid, Spain;Search for other works by this author on:Marco Bissig;Marco BissigcServzio di Farmacia,Ospedale Civico Lugano, Lugano, Switzerland;Search for other works by this author on:Jaak Damiaans;Jaak Damiaansd Pharmacy Department, Virga Jesse Hospital, Hasselt, Belgium;Search for other works by this author on:Irene Krämer;Irene KrämerePharmacy Department, Johannes Gutenberg-University Hospital, Mainz, Germany;Search for other works by this author on:Patrick Rambourg;Patrick RambourgfPharmacie Saint-Eloi, CHU de Montpellier, Montpellier, France;Search for other works by this author on:Giovanna Scroccaro;Giovanna ScroccarogServizio di Farmacia, A.O., Verona, Italy;Search for other works by this author on:Borut Strukelj;Borut StrukeljhFaculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia;Search for other works by this author on:Roger Tredree;Roger TredreeiPharmacy Department, St George’s Hospital, London, UK;Search for other works by this author on:Claudio RoncoClaudio RoncojDipartimento Interaziendale di Nefrologia Dialisi e Trapianto Renale, Ospedale San Bortolo, Vicenza, ItalySearch for other works by this author on:
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295 - 305: Electrophysiological Response to Dialysis: The Role of Dialysate Potassium Content and ProfilingByA. Santoro;A. SantoroaMalpighi Nephrology Division, Policlinico S. Orsola-Malpighi, Bologna, Italy,Search for other works by this author on:E. Mancini;E. ManciniaMalpighi Nephrology Division, Policlinico S. Orsola-Malpighi, Bologna, Italy,Search for other works by this author on:R. Gaggi;R. GaggiaMalpighi Nephrology Division, Policlinico S. Orsola-Malpighi, Bologna, Italy,Search for other works by this author on:S. Cavalcanti;S. CavalcantibBiomedical Engineering Laboratory, DEIS, University of Bologna, Bologna,Search for other works by this author on:S. Severi;S. SeveribBiomedical Engineering Laboratory, DEIS, University of Bologna, Bologna,Search for other works by this author on:L. Cagnoli;L. CagnolicNephrology Department, Ospedale Degli Infermi, Rimini, Italy,Search for other works by this author on:F. Badiali;F. BadialicNephrology Department, Ospedale Degli Infermi, Rimini, Italy,Search for other works by this author on:B. Perrone;B. PerronedCentre Hospitalier F.H. Manhes, Fleury-Mérogis,Search for other works by this author on:G. London;G. LondoneUnité de Nèphrologie et Dialyse, Hôpital René Dubos, Pontoise,Search for other works by this author on:L. Mercadal;L. MercadalgService de Néphrologie, Hopital La Pitié, Paris, France, andSearch for other works by this author on:F. GrandiF. GrandihHospal S.p.A., Bologna, ItalySearch for other works by this author on:
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306 - 314: Noninvasive Assessment of Vascular FunctionByDaniel Schneditz,;Daniel Schneditz,Institute of Physiology, Medical University Graz, Graz, AustriaSearch for other works by this author on:Thomas KennerThomas KennerInstitute of Physiology, Medical University Graz, Graz, AustriaSearch for other works by this author on:
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315 - 324: New Insights in Uremic ToxicityByR. Vanholder;R. VanholderNephrology Section, Department of Internal Medicine,University Hospital, Ghent, BelgiumSearch for other works by this author on:G. Glorieux;G. GlorieuxNephrology Section, Department of Internal Medicine,University Hospital, Ghent, BelgiumSearch for other works by this author on:GN. LameireGN. LameireNephrology Section, Department of Internal Medicine,University Hospital, Ghent, BelgiumSearch for other works by this author on:
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325 - 333: Continuous Renal Replacement Therapy for End-Stage Renal Disease: The Wearable Artificial Kidney (WAK)ByVictor Gura;Victor GuraaCedars Sinai Medical Center, UCLA, and Geffen School of Medicine, Beverly Hills, Calif., USA.Search for other works by this author on:Masoud Beizai;Masoud Beizaib National Quality Care Inc., Beverly Hills, Calif., USASearch for other works by this author on:Carlos Ezon;Carlos Ezonb National Quality Care Inc., Beverly Hills, Calif., USASearch for other works by this author on:Hans-Dietrich PolascheggHans-Dietrich Polascheggb National Quality Care Inc., Beverly Hills, Calif., USASearch for other works by this author on:
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334 - 342: Slow Continuous Intravenous Plasmapheresis (SCIPTM): Clinical Applications and Hemostability of Extracorporeal UltrafiltrationByHarold H. Handley;Harold H. HandleyaTransvivo, Inc., Napa, Calif.,Search for other works by this author on:Harold Peters;Harold PetersaTransvivo, Inc., Napa, Calif.,Search for other works by this author on:Thomas G. Cooper;Thomas G. Cooperb Cooper Consulting Services, Friendswood, Tex.,Search for other works by this author on:Richard H. Bien;Richard H. BiencQueen of the Valley Hospital, Napa, Calif., andSearch for other works by this author on:Nathan W. Levin;Nathan W. Levind Renal Research Institute, New York, N.Y., USA;Search for other works by this author on:Claudio RoncoClaudio RoncoeSt. Bortolo Hospital, Department of Nephrology,Vicenza, ItalySearch for other works by this author on:
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343 - 353: Membraneless Dialysis – Is It Possible?ByEdward F. Leonard;Edward F. LeonardaDepartments of Chemical and Biomedical Engineering, Columbia University,Search for other works by this author on:Stanley Cortell;Stanley CortellbDivision of Nephrology, St. Luke’s – Roosevelt Hospital Center, New York,Search for other works by this author on:Nicholas G. VitaleNicholas G. VitalecInfoscitex Inc., Albany, N.Y., USASearch for other works by this author on: