Abnormalities in Puberty: Scientific and Clinical Advances
This book on abnormalities in puberty presents an overview on the latest knowledge on the mechanisms of the developmental processes of puberty. Although the exact mechanisms of reawakening of the GnRH pulse generator at the onset of puberty still have to be elucidated, many genetic and environmental factors have been identified to play a major role. Topics discussed in individual chapters include the endocrine and metabolic issues related to the 'developmental origin of adult disease' hypothesis and polycystic ovary syndrome as well as abnormalities in GnRH controlling genes, GnRH-secreting hamartoma as a model for the onset of puberty, experience on the application of GnRH analogues in the treatment of central precocious puberty, and the psychosocial effects of an early puberty. This volume provides the paediatrician, endocrinologist, gynaecologist and general practitioner with underlying information as well as practical tokens on how to manage the various conditions of a disturbed process of puberty.
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Table of Contents
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1 - 14: Secular Trend of Timing of PubertyByHenriette Delemarre-van de WaalHenriette Delemarre-van de WaalVU University Medical Center, Amsterdam, The NetherlandsSearch for other works by this author on:
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15 - 33: Fetal Nutrition and Timing of PubertyByM.M. van Weissenbruch;M.M. van WeissenbruchDepartment of Pediatrics, Research Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The NetherlandsSearch for other works by this author on:M.J.T. Engelbregt;M.J.T. EngelbregtDepartment of Pediatrics, Research Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The NetherlandsSearch for other works by this author on:M.A. Veening;M.A. VeeningDepartment of Pediatrics, Research Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The NetherlandsSearch for other works by this author on:H.A. Delemarre-van de WaalH.A. Delemarre-van de WaalDepartment of Pediatrics, Research Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The NetherlandsSearch for other works by this author on:
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34 - 53: Adrenal Function of Low-Birthweight ChildrenByKen OngKen OngDepartment of Paediatrics, University of Cambridge,Addenbrooke’s Hospital, Cambridge, UKSearch for other works by this author on:
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54 - 66: Puberty and Fertility in Congenital Adrenal HyperplasiaByB.J. Otten;B.J. OttenaDepartments of Pediatric Endocrinology, andSearch for other works by this author on:M.M.L. Stikkelbroeck;M.M.L. Stikkelbroeckb Endocrinology, University Hospital St. Radboud, Nijmegen, The NetherlandsSearch for other works by this author on:H.L. Claahsen-van der Grinten;H.L. Claahsen-van der GrintenaDepartments of Pediatric Endocrinology, andSearch for other works by this author on:A.R.M.M. HermusA.R.M.M. Hermusb Endocrinology, University Hospital St. Radboud, Nijmegen, The NetherlandsSearch for other works by this author on:
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67 - 80: Molecular Genetics of Isolated Hypogonadotropic Hypogonadism and Kallmann SyndromeByBeate Karges;Beate KargesaUniversity Children’s Hospital, University of Ulm, Ulm, Germany;Search for other works by this author on:Nicolas de RouxNicolas de RouxbINSERM U584, Hormone Targets, Medical Faculty Necker-Enfants Malades, and University Paris XI, Paris, FranceSearch for other works by this author on:
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81 - 93: Hypothalamic Hamartoma: A Paradigm/Model for Studying the Onset of PubertyByHeike Jung,;Heike Jung,Division of Neuroscience, Oregon National Primate Research Center/Oregon Health & Science University, Beaverton, Oreg., USASearch for other works by this author on:Anne-Simone Parent,;Anne-Simone Parent,Division of Neuroscience, Oregon National Primate Research Center/Oregon Health & Science University, Beaverton, Oreg., USASearch for other works by this author on:Sergio R. OjedaSergio R. OjedaDivision of Neuroscience, Oregon National Primate Research Center/Oregon Health & Science University, Beaverton, Oreg., USASearch for other works by this author on:
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94 - 125: Gonadotropin-Releasing Hormone Analogue Treatment for Precocious Puberty: Twenty Years of ExperienceBySabine Heger;Sabine HegeraDivision of Paediatric Endocrinology, Department of Paediatrics, Christian-Albrechts-Universität, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, andSearch for other works by this author on:Wolfgang G. Sippell;Wolfgang G. SippellaDivision of Paediatric Endocrinology, Department of Paediatrics, Christian-Albrechts-Universität, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, andSearch for other works by this author on:Carl-Joachim PartschCarl-Joachim PartschbKlinik für Kinder und Jugendliche, Städtische Kliniken,Esslingen, GermanySearch for other works by this author on:
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126 - 136: Very Long-Term Follow-Up of Girls with Early and Late MenarcheByTherése Johansson;Therése JohanssonaDepartment of Behavioural, Social and Legal Sciences, Örebro University, Örebro, andSearch for other works by this author on:E. Martin RitzénE. Martin Ritzénb Department of Woman and Child Health, Karolinska Institute,Stockholm, SwedenSearch for other works by this author on:
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137 - 149: Polycystic Ovary Syndrome in Adolescence: New Insights in Pathophysiology and TreatmentByR. HomburgR. HomburgDivision of Reproductive Medicine, Department of Obstetrics and Gynaecology, Vrije Universiteit Medical Centre, Amsterdam, The NetherlandsSearch for other works by this author on:
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150 - 165: Reversing Sex Steroid Deficiency and Optimizing Skeletal Development in the Adolescent with Gonadal FailureByDirk Vanderschueren;Dirk VanderschuerenaLaboratory for Experimental Medicine and Endocrinology, andSearch for other works by this author on:Liesbeth Vandenput;Liesbeth VandenputaLaboratory for Experimental Medicine and Endocrinology, andSearch for other works by this author on:Steven BoonenSteven BoonenaLaboratory for Experimental Medicine and Endocrinology, andbLeuven University Centre for Metabolic Bone Diseases and Division of Geriatric Medicine, Katholieke Universiteit Leuven, Leuven, BelgiumSearch for other works by this author on:
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166 - 175: Present and Future Options for the Preservation of Fertility in Female Adolescents with CancerByC.C.M. Beerendonk;C.C.M. BeerendonkDepartment of Obstetrics and Gynaecology,University Medical Centre St Radboud, Nijmegen, The NetherlandsSearch for other works by this author on:D.D.M. BraatD.D.M. BraatDepartment of Obstetrics and Gynaecology,University Medical Centre St Radboud, Nijmegen, The NetherlandsSearch for other works by this author on: