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Pediatric and Adolescent Medicine
Neonatal Pharmacology and Nutrition Update
S.Karger AG
Volume
18
Status:
Available
ISBN electronic:
978-3-318-02736-5
ISBN print:
978-3-318-02735-8
Subject Area:
Further Areas
,
Nutrition and Dietetics
,
Pharmacology
,
Women's and Children's Health
Book Series:
Pediatric and Adolescent Medicine
Publication date:
2014
Book Details
In order to provide safe and effective drug therapy to neonates, it is necessary to know about and understand the impact their development has on the pharmacokinetics and pharmacodynamics of drugs. The fact that children are different and neonates very different from adults means that, in neonates, it would be unwise to dose medications by scaling down adult doses proportionately, simply attempting to match their smaller weight and/or body surface area. When one makes decisions about neonatal drug therapy, one must not only take into consideration the available data but also critically assess and interpret this information within the context of fetal development and maturational processes as well as within the context of diseases that might affect a drug’s biodisposition. This book includes the latest information on the regulation and scientific basis of drug development and also provides a rationale for formula development for preterm infants. It offers guidance on how to translate pharmacokinetic data into dosing recommendations and also covers legal and regulatory issues relating to neonatal pharmacotherapy.
Neonatal Pharmacology and Nutrition Update
Edited by: F.B. Mimouni, J.N. van den Anker
https://doi.org/10.1159/isbn.978-3-318-02736-5
ISBN (print): 978-3-318-02735-8
ISBN (electronic): 978-3-318-02736-5
Publisher: S.Karger AG
Published: 2014
Download citation file:
Digital Version
Pay-Per-View Access
$148.00
Print Version
Neonatal Pharmacology and Nutrition Update
$148.00
Table of Contents
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1 - 12: Influence of Maturation and Growth on Drug Metabolism from Fetal to Neonatal to Adult LifeBySynnöve Lindemalm;Synnöve LindemalmaAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden;Search for other works by this author on:Johannes N. van den AnkerJohannes N. van den AnkerbDivision of Pediatric Clinical Pharmacology, Children's National Medical Center, Washington, DC, andcDepartments of Pediatrics, Pharmacology, Physiology and Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA;dIntensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands;eDepartment of Paediatric Pharmacology, University Children's Hospital, Basel, SwitzerlandSearch for other works by this author on:
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13 - 27: How to Translate Pharmacokinetic Data into Dosing RecommendationsByElke H.J. Krekels;Elke H.J. KrekelsaIntensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands;bDivision of Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands;Search for other works by this author on:Catherijne A.J. Knibbe;Catherijne A.J. KnibbeaIntensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands;bDivision of Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands;Search for other works by this author on:Paula Pokorna;Paula PokornaaIntensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands;cIntensive Care Department of Pediatrics, First Medical Faculty, Charles University, Prague, Czech RepublicSearch for other works by this author on:Dick TibboelDick TibboelaIntensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands;Search for other works by this author on:
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28 - 40: Pharmacovigilance in Neonatal Intensive CareByMark A. Turner;Mark A. TurnerDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UKSearch for other works by this author on:Helen HillHelen HillDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UKSearch for other works by this author on:
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41 - 57: Neonatal Formulations and AdditivesByKarel Allegaert;Karel AllegaertaNeonatal Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium;Search for other works by this author on:Mark A. Turner;Mark A. TurnerbDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UK;Search for other works by this author on:John N. van den AnkerJohn N. van den AnkercDivision of Pediatric Clinical Pharmacology, Children's National Medical Center, Washington, DC, anddDepartments of Pediatrics, Pharmacology, Physiology and Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington DC, USA;eIntensive Care, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands;fDepartment of Paediatric Pharmacology, University Children's Hospital, Basel, SwitzerlandSearch for other works by this author on:
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58 - 69: Modelling and Simulation to Support Neonatal Clinical TrialsByFeras Khalil;Feras KhalilDepartment of Clinical Pharmacy and Pharmacotherapy, Heinrich-Heine University of Düsseldorf, Düsseldorf, GermanySearch for other works by this author on:Stephanie LäerStephanie LäerDepartment of Clinical Pharmacy and Pharmacotherapy, Heinrich-Heine University of Düsseldorf, Düsseldorf, GermanySearch for other works by this author on:
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70 - 82: A Systematic Review of Paracetamol and Closure of Patent Ductus Arteriosus: Ready for Prime Time?ByCathy Hammerman;Cathy HammermanaDepartment of Neonatology, Shaare Zedek Medical Center, Jerusalem,bHebrew University, Faculty of Medicine, Jerusalem, andSearch for other works by this author on:Francis B. Mimouni;Francis B. MimouniaDepartment of Neonatology, Shaare Zedek Medical Center, Jerusalem,cTel Aviv University, Sackler School of Medicine, Tel Aviv, IsraelSearch for other works by this author on:Alona Bin-NunAlona Bin-NunaDepartment of Neonatology, Shaare Zedek Medical Center, Jerusalem,Search for other works by this author on:
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83 - 107: Formulation of Preterm Formula: What's in it, and Why?ByFrancis B. Mimouni;Francis B. MimouniaDepartment of Neonatology, Shaare Zedek Medical Center, Jerusalem,bDepartment of Pediatrics, The Tel Aviv Medical Center, Tel Aviv,Search for other works by this author on:Dror Mandel;Dror MandelbDepartment of Pediatrics, The Tel Aviv Medical Center, Tel Aviv,cSackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelSearch for other works by this author on:Ronit LubetzkyRonit LubetzkybDepartment of Pediatrics, The Tel Aviv Medical Center, Tel Aviv,cSackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelSearch for other works by this author on:
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108 - 123: Neonatal Pharmacotherapy: Legal and Regulatory IssuesByRalph Bax;Ralph BaxPaediatric Medicines, Product Development Scientific Support Department, European Medicines Agency, Canary Wharf, London, UKSearch for other works by this author on:Paolo TomasiPaolo TomasiPaediatric Medicines, Product Development Scientific Support Department, European Medicines Agency, Canary Wharf, London, UKSearch for other works by this author on:
